Virology Journal, 2010 Background Hepatitis C is an infectious disease affecting the liver, caused by the hepatitis C virus (HCV). The hepatitis C virus is a small, enveloped, single-stranded, positive sense RNA virus with a large genetic heterogeneity.
Kardi Mohammad T +2 more
doaj +1 more source
Ledipasvir/Sofosbuvir Is Effective for Relapsed Genotype 1b Hepatitis C Virus Patients after Achieving a Sustained Virological Response at Post-treatment Week 12 with Glecaprevir/Pibrentasvir. [PDF]
Intern Med, 2023 Manabe T +8 more
europepmc +1 more source
, 2011 International audienceThe efficiencies of IFN-α based therapy in chronic genotype 1b HCV patients are still unsatisfied to date. The mechanisms underlining treatment failure remain unclear and controversial.
Zhou, Xiaqiu +19 more
core +1 more source
Mechanically Programmable DNA Hydrogel Microparticles for 3D Cellular Systems
Advanced Materials, EarlyView.DNA hydrogel microparticles are designed to exhibit controllable viscoelasticity and stiffness across three orders of magnitude from 30Pa$30 \,\mathrm{Pa}$ to 6.5kPa$6.5 \,\mathrm{kPa}$. They are uptaken into fibroblast spheroids where they are actively remodeled by cellular forces depending on their mechanical properties.
Tobias Walther +9 more
wiley +1 more source
Direct-Acting Antiviral Use for Genotype 1b Hepatitis C Patients with Associated Hematological Disorders from Romania. [PDF]
Medicina (Kaunas), 2021 Marincu I +6 more
europepmc +1 more source
Collision‐Resilient Winged Drones Enabled by Tensegrity Structures
Advanced Robotics Research, EarlyView.Based on structures of birds such as the woodpeck, this article presents the collision‐resilient aerial robot, SWIFT. SWIFT leverages tensegrity structures in the fuselage and wings which allow it to undergo large deformations in a crash, without sustaining damage. Experiments show that SWIFT can reduce impact forces by 70% over conventional structures.
Omar Aloui +5 more
wiley +1 more source
Genetic polymorphism of hepatitis C virus and risk of hepatocellular carcinoma
Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2014 The aim of review. To estimate effect of genetic polymorphism of hepatitis C virus on risk of hepatocellular carcinomas (HCC).Key points. Hepatocellular carcinoma is one of the most dreadful outcomes of chronic liver diseases, in particular — chronic ...
S. N. Mammayev, A. M. Karimova
doaj
Naturally occurring mutations to HCV protease inhibitors in treatment-naïve patients
Virology Journal, 2012 Background Protease inhibitors (PIs) to treat hepatitis C (HCV) virus infection have been approved and others are under development. Results The aims of this study were to illustrate natural polymorphisms in the HCV protease and measure the frequency of ...
Paolucci Stefania +9 more
doaj +1 more source
Genetic Determinants in a Critical Domain of NS5A Correlate with Hepatocellular Carcinoma in Cirrhotic Patients Infected with HCV Genotype 1b. [PDF]
Viruses, 2021 Alkhatib M +29 more
europepmc +1 more source
Endocrinology Insights, 2014 AbstractObjectivePseudohypoparathyroidism type 1b (PHP1b) results from methylation defects in the maternal GNAS locus. It is implied that the observed hypocalcemia results from impairment of renal vitamin D 1α hydroxylase. This study was undertaken to clarify: (1) How serum concentrations of calcium, phosphate, PTH and 1,25 dihydroxy vitamin D (1 ...
Sobrinho, Luis G. +2 more
openaire +1 more source