Results 91 to 100 of about 1,309,818 (329)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Coppice potential of 16 different species of Eucalyptus after an eight-year rotation [PDF]

open access: yes, 2019
The adoption of coppice is a commonly used management in different regions of Brazil for plantations of Eucalyptus, which requires less investments. However, there are variations in the ability of each genotype to emit sprouts, and higher yields can be ...
Campoe, Otávio   +3 more
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Genotypic variations of Porphyromonas gingivalis in chronic periodontitis patients with and without diabetes: An in vitro study using arbitrarily primed-polymerase chain reaction and heteroduplex-polymerase chain reaction

open access: yesJournal of Indian Society of Periodontology, 2019
Context: Diabetes has become an endemic throughout the world. Periodontitis is associated with diabetes, and it has been regarded as the sixth complication of diabetes.
Siladitya Sen, Kukkamalla Meena Anand
doaj   +1 more source

Splitting pairs and the number of clusters generated by random pair incompatibilities

open access: yes, 2007
We consider a random fitness landscape on the space of haploid diallelic genotypes with n genetic loci, where each genotype is considered either inviable or viable depending on whether or not there are any incompatibilities among its allele pairs.
Pitman, Damien
core  

Circular 79 [PDF]

open access: yes, 1990
The development of improved cultivars of barley is accomplished through comprehensive plant breeding programs. Such programs: 1). evaluate genetically-diverse germplasm in order to identify superiorperforming genotypes; 2).
Blake, S.A., Dofing, S.M.
core  

HIV-1 molecular diversity in Brazil unveiled by 10 years of sampling by the national genotyping network [PDF]

open access: gold, 2021
Tiago Gräf   +13 more
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Human Papillomavirus Genotype Distribution in Penile Cancer: Clinical, Histopathological, Radiological Correlations, and Public Health Perspectives

open access: yesIndian Journal of Public Health
Human papillomavirus (HPV) appears to play an important role in the development of penile cancer. Research indicates geographical variations in HPV prevalence in penile cancer.
Bulbul Roy   +4 more
doaj   +1 more source

Performance and feed intake of five beef suckler cow genotypes and pre-weaning growth of their progeny [PDF]

open access: yes, 2008
peer-reviewedThe effect of beef suckler cow genotype on feed intake, performance, milk yield and on pre-weaning growth of their progeny was determined over four lactations.
Drennan, Michael J   +3 more
core  

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