Results 81 to 90 of about 1,921,022 (384)

Search for Risk Haplotype Segments with GWAS Data by Use of Finite Mixture Models [PDF]

open access: yes, 2015
The region-based association analysis has been proposed to capture the collective behavior of sets of variants by testing the association of each set instead of individual variants with the disease.
Ali, Fadhaa, Zhang, Jian
core   +1 more source

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

open access: yesMolecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci   +6 more
wiley   +1 more source

Molecular clones of genetically distinct hepatitis B virus genotypes reveal distinct host and drug treatment responses

open access: yesJHEP Reports, 2022
Background & Aims: HBV exhibits wide genetic diversity with at least 9 genotypes (GTs), which differ in terms of prevalence, geographic distribution, natural history, disease progression, and treatment outcome. However, differences in HBV replicative
Yongzhen Liu   +10 more
doaj  

Studies on the interrelationship between yield and agronomic traits in some selected soybean lines at Yandev in Southern Guinea Savannah of Nigeria [PDF]

open access: yesJournal of Plant Development, 2018
A field trial was conducted during the 2010 cropping season at the experimental farm of Akperan Orshi College of Agriculture, Yandev–Gboko, Benue State. The plots were laid in Randomized Complete Block Design with three replications.
Gabriel Ojonimi ABIMAJE   +3 more
doaj   +1 more source

Physiological analysis of salt stress behaviour of citrus species and genera: low chloride accumulation as an indicator of salt tolerance : S08O07 [PDF]

open access: yes, 2012
Tolerant citrus rootstocks are defined as Cl- excluders. However, little is known about the salt tolerance of cultivars used as scions, particularly the tolerance of monoembryonic citrus genotypes. To enhance the genetic resources for generating improved
Costantino, Gilles   +4 more
core  

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

Drought stress tolerance strategies revealed by RNA-Seq in two sorghum genotypes with contrasting WUE

open access: yesBMC Plant Biology, 2016
Drought stress is the major environmental stress that affects plant growth and productivity. It triggers a wide range of responses detectable at molecular, biochemical and physiological levels.
Alessandra Fracasso   +2 more
semanticscholar   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

The Most Frequent HPV Genotypes in Women with Cervical Cancer in Southwest of Iran [PDF]

open access: yesWomen’s Health Bulletin, 2018
Background: Cervical cancer ranked as the most common cancer of women in developing countries. Human Papillomaviruses (HPVs) belongs to the Papillomaviridea family, which is able to infect humans.
Mojtaba Oraki Kohshour   +4 more
doaj   +1 more source

Field Screening of Lentil Genotypes Against Aphid Infestation in Inner Tarai of Nepal [PDF]

open access: yes, 2020
Twenty lentil (Lens culinaris Medik) genotypes received from Grain Legumes Research Program, Khajura, Banke were screened for relative tolerance against aphid (Aphis craccivora Koch.) at the research field of National Maize Research Program, Rampur ...
Darai, R. (Rajendra)   +2 more
core  

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