Results 81 to 90 of about 43,318 (306)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

GENETIC VARIABILITY, GENOTYPIC AND PHENOTYPIC CORRELATIONS BETWEEN ECONOMIC TRAITS OF MAIZE UNDER DIFFERENT DATES OF PLANTING [PDF]

Journal of Plant Production, 2005
New early 27 yellow three-way crosses of maize were evaluated at two planting dates (early and late). Genotypic and phenotypic variation, correlation coefficients, heritability in the broad sense and heterosis were estimated for six economic traits ...
A. EI·Shenawy, H. Mosa,
doaj   +1 more source

Estimating and testing the effect of allelic recombination on the correlation between genotypic relatives

, 2013
This paper provides estimates of the correlation between genotypic relatives and the effect of allelic recombination on the correlation assuming random mating. It is shown that the correlation is a non negative quantity and that allelic recombination has
Oyeka, CA, Oyeka, ICA, Uzuke, CA
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Genetic Diversity Among some Potato Varieties For In Vitro Microtuberisation under Salinity Stress [PDF]

Journal of Agricultural Chemistry and Biotechnology
This study was carried out to investigate the tolerance to salinity stress, using three cultivated varieties. These cultivars were Diamant, Spunta and Cara.
Rahma Abo Saleh, Eman Abd El-Monem, M. Abdel-Maksoud   +2 more
doaj   +1 more source

Inter and intragroup phenotypic variance.

, 2012
Mean phenotypic value and variance of each group are calculated and plotted against mean genotypic value of the group. Errorbars represent intragroup variance.
Barbora Trubenová (114028), Reinmar Hager (114035)   +1 more
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Clonal selection in S0 and S1 peach trees evaluated in a subtropical environment

Crop Breeding and Applied Biotechnology, 2021
The aims of this study were to estimate genetic parameters, predict genotypic values, and analyze the genotypic divergence in S0 and S1 peach trees evaluated in a subtropical environment by the mixed model methodology.
José Osmar da Costa e Silva, Claudio Horst Bruckner, Pedro Crescêncio Souza Carneiro, Marcos Deon Vilela de Resende, Rodrigo Silva Alves, Mariana Rodrigues Ribeiro, Danielle Fabíola Pereira da Silva   +6 more
doaj  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source