Results 161 to 170 of about 58,106,402 (334)
, 2015 The Biospectra-by-sequencing (BBS) project started in 2014. It is a collaborative multi-institutional effort to build a robust genetic analysis platform. It initially focused on open-source Genotyping-bysequencing (GBS) technology.
Roger Moraga (517238) +14 more
core
Stage‐Specific Patterns of Imaging and Non‐Motor Biomarkers in Spinocerebellar Ataxia Type 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Advancements in disease‐modifying therapies for spinocerebellar ataxia Type 3 (SCA3) underscore the need for robust biomarkers to monitor disease progression and evaluate treatment efficacy. Although motor phenotypes have been well characterized, less is known about non‐motor and imaging‐based features across different disease stages.
Chun Li +17 more
wiley +1 more source
The Association of Amyloid‐β and Tau With Synaptic Dysfunction in Alzheimer's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To clarify the relative contributions of amyloid and tau to synaptic dysfunction in Alzheimer's disease (AD). Methods We included 109 cognitively unimpaired and impaired individuals from the Geneva Memory Center with available CSF synaptic biomarkers (neurogranin, SNAP‐25, GAP‐43). Participants were stratified according to amyloid (A)
Fausto Roveta +11 more
wiley +1 more source
Application of Genotyping-by-Sequencing (GBS) in Livestock
, 2016 Advances in next generation sequencing technology have increased the output/cost ratio to a level where cost effective genotyping-by-sequencing (GBS) in livestock, plants and aquaculture species is now a reality.
Rudiger Brauning (47247) +5 more
core +1 more source
Genotyping-by- Sequencing of the Southern Toad
, 2015 Genotyping-by- Sequencing of the Southern ...
Patel, Rishva, Nguyen, Tammy
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Inherited ataxias are clinically diverse neurodegenerative diseases, complicating the choice of outcome measures for trials. In spinocerebellar ataxia (SCA), regulatory concerns about the Scale for the Assessment and Rating of Ataxia (SARA) caused a shift toward functional SARA (f‐SARA), contributing to pivotal trial failure.
Christian Rummey +52 more
wiley +1 more source
Genetic diversity and population structure analysis in Asparagus officinalis
Journal of Genetic Engineering and BiotechnologyAsparagus cultivars grown worldwide are thought to have originated from a limited genetic base, however, selection has resulted in variation for climatic adaptation and other traits.
Gurleen Sidhu, Travis Banks, David Wolyn
doaj +1 more source
Estimating linkage disequilibrium using genotyping-by-sequencing data
, 2017 Genotyping-by-sequencing (GBS) is a cost effective procedure for simultaneously performing single-nucleotide polymorphism discovery and genotyping.
Ken Dodds (3501542) +1 more
core
Arthritis Care &Research, EarlyView.Biomedical research involving US veterans continues to advance health care beyond the Veterans Health Administration. This is particularly true in rheumatoid arthritis (RA), where veteran‐centric research has uncovered novel insights into pathogenesis, risk factors, and disease manifestations, informing clinical care and research across both veteran ...
Austin M. Wheeler +20 more
wiley +1 more source
Ecology and EvolutionSpecies syngameons are groups of more than two hybridizing species that form complex hybrid networks. Syngameons facilitate sharing the gene pool among species while maintaining morphological differentiation.
Manuel Curto +2 more
doaj +1 more source