Results 91 to 100 of about 456,399 (317)

Serological and RHD genotyping characteristics of RhD-negative populations in primary screening in Beijing

Zhongguo shuxue zazhi
Objective To study the RHD genotyping of primary screening RhD negative population in Beijing, and analyze the serological characteristics of different genotypes and the distribution of Rh phenotypes.
Ke SONG, Chunya MA, Yuanyuan LUO, Yang YU   +3 more
doaj   +1 more source

Genotyping of Infectious Laryngotracheitis Virus (ILTV) Isolates from Western Canadian Provinces of Alberta and British Columbia Based on Partial Open Reading Frame (ORF) a and b

Animals, 2020
Infectious laryngotracheitis virus (ILTV) causes an acute upper respiratory disease in chickens called infectious laryngotracheitis (ILT). Live attenuated vaccines are effective in disease control; however, they have residual virulence, which makes them ...
Catalina Barboza-Solis, Ana Perez Contreras, Victor A. Palomino-Tapia, Tomy Joseph, Robin King, Madhu Ravi, Delores Peters, Kevin Fonseca, Carl A. Gagnon, Frank van der Meer, Mohamed Faizal Abdul-Careem   +10 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Unusual BA222-like strains of Rotavirus A (Sedoreoviridae: Rotavirus: Rotavirus A): molecular and genetic analysis based on all genome segments

Вопросы вирусологии
Introduction. Rotavirus infection is the major cause of severe dehydrating diarrhea requiring hospitalization in young children worldwide. Due to their segmented genome, rotaviruses are capable of gene reassortment, which makes the emergence and spread ...
Elena I. Velikzhanina, Tatiana A. Sashina, Olga V. Morozova, Alexander Yu. Kashnikov, Natalia V. Epifanova, Nadezhda A. Novikova   +5 more
doaj   +1 more source

Mis-Genotyping of Some Hepatitis D Virus Genotype 2 and 5 Sequences Using HDVdb

Viruses, 2020
Evidence that Hepatitis D virus (HDV) genotype is involved in HDV infection pathogenesis is increasing. Indeed, HDV genotypes have been shown to be linked to different outcomes in terms of liver fibrosis and treatment response.
Caroline Charre, Frédéric le Gal, Paul Dény, Caroline Scholtès   +3 more
doaj   +1 more source

SNP Genotyping and ApoE Genotyping v1

, 2021
This protocol details the steps for DNA extraction from a human blood sample, quality control, and SNP and APOE genotyping. The protocol has been adapted from the PRoBaND SNP Genotyping and ApoE Genotyping Protocol. The overall protocol for PRoBaND /Tracking Parkinson’s is published: Malek, N., Swallow, D. M. A., Grosset, K. A., Lawton, M.
Huw Morris, Manuela MX Tan, Donald G Grosset, Nigel M Williams   +3 more
openaire   +1 more source

Plasmodium falciparum msp1, msp2 and glurp allele frequency and diversity in sub-Saharan Africa. [PDF]

, 2011
The efficacy of anti-malarial drugs is assessed over a period of 28-63 days (depending on the drugs' residence time) following initiation of treatment in order to capture late failures.
Sumari Deborah, Beck, Hans-Peter, Beck, H. P., Mwingira Felista, Hans-Peter Beck, Olliaro, P., Beck Hans-Peter, Mugittu, K., Felger Ingrid, Felger, Ingrid, Sonja Schoepflin, Nkwengulila, Gamba, Schöpflin, S., Ingrid Felger, Deborah Sumari, Georges Snounou, Mwingira, Felista, Olliaro Piero, Kefas Mugittu, Schoepflin, Sonja, Mwingira, F., Sumari, Deborah, Felista Mwingira, Mugittu Kefas, Piero Olliaro, Schoepflin Sonja, Snounou, G., Felger, I., Nkwengulila Gamba, Mugittu, Kefas, Snounou, Georges, Snounou Georges, Nkwengulila, G., Sumari, D., Olliaro, Piero, Gamba Nkwengulila   +35 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Molecular Characterization of Clostridium perfringens Strains Isolated in Italy

Toxins, 2020
Clostridium (C.) perfringens is the causative agent of several diseases and enteric infections in animals and humans. The pathogenicity of the bacterium is largely mediated by the production of a wide range of toxins. Individual C.
Katia Forti, Laura Ferroni, Martina Pellegrini, Deborah Cruciani, Antonio De Giuseppe, Silvia Crotti, Paola Papa, Carmen Maresca, Giulio Severi, Maria Luisa Marenzoni, Monica Cagiola   +10 more
doaj   +1 more source

Genotyping-by-sequencing

, 2016
Genotyping-by-sequencing: Emerging alternative technology to array based genotyping for GBLUP & GWAS. Two “categories” - oligo directed re-sequencing of specific regions -targeted; reduced representational re-sequencing- restriction enzyme digests ...
Ken Dodds (3501542), Rudiger Brauning (47247), Shannon Clarke (3504989), John McEwan (45371)   +3 more
core