Results 81 to 90 of about 456,399 (317)

Molecular Characterization of African Swine Fever Virus Isolates in Estonia in 2014–2019

Pathogens, 2020
After the extensive spread of the African swine fever virus (ASFV) genotype II in Eastern Europe, the first case of African swine fever (ASF) in Estonia was diagnosed in September 2014. By the end of 2019, 3971 ASFV-positive wild boars were found, and 27
Annika Vilem, Imbi Nurmoja, Tarmo Niine, Taavi Riit, Raquel Nieto, Arvo Viltrop, Carmina Gallardo   +6 more
doaj   +1 more source

Palmer Lab High Coverage WGS DeepVariant Genotyping Pipeline

, 2023
<p>The very first version of Palmer Lab's High Coverage WGS DeepVariant Genotyping Pipeline v1.0.0. Acceptable sequencing data: High Coverage WGS</p>If you use this pipeline or use data generated by this pipeline, please cite it as ...
Chitre, Apurva, Cheng, Riyan, Palmer, Abraham, Polesskaya, Oksana, Chen, Denghui, Peng, Beverly   +5 more
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

The effect of LGB gene polymorphism on milk productivity indicators of Kholmogorsky cows

RUDN Journal of Agronomy and Animal Industries
In modern breeding work, considerable attention is paid to genetic resources of cattle, genetic assessment of which, with proper crossbreeding and selection, can increase efficiency of the entire industry.
Natalya A. Khudyakova, Ekaterina N. Shchipakova, Andrey S. Kashin   +2 more
doaj   +1 more source

vgteam/sv-genotyping-paper: Code repository for "Genotyping structural variants in pangenome graphs using the vg toolkit"

, 2019
<p>This repository contains the commands and scripts used for <a href="https://jmonlong.github.io/manu-vgsv/v/35852320569f679f1ded48e162a4b7f48a9cb158/">Genotyping structural variants in pangenome graphs using the vg toolkit, 2019</a> (&
Jean Monlong, Glenn Hickey, David Heller
core   +1 more source

High-throughput high-resolution class I HLA genotyping in East Africa. [PDF]

, 2010
HLA, the most genetically diverse loci in the human genome, play a crucial role in host-pathogen interaction by mediating innate and adaptive cellular immune responses. A vast number of infectious diseases affect East Africa, including HIV/AIDS, malaria,
Leonard Maboko, Eller, Michael, Jerome Kim, Rebecca N Koehler, Francine E McCutchan, Michael Eller, Christian T Bautista, Hoelscher Michael, Eller, Leigh Anne, Jeffrey R Currier, Currier Jeffrey R., Nelson L Michael, Michael, Nelson L., Kijak, Gustavo H, Maboko Leonard, Michael, Nelson L, McCutchan, Francine E., Michael Nelson L., Maboko, Leonard, Walsh, Anne M, Wabwire-Mangen Fred, Fred Wabwire-Mangen, Wabwire-Mangen, Fred, Currier, Jeffrey R, Eller Michael, McCutchan, Francine E, Eric E Sanders-Buell, Sanders-Buell, Eric E., Robb, Merlin L, Robb Merlin L., Kijak Gustavo H., Leigh Anne Eller, Kim Jerome, Robb, Merlin L., Bautista Christian T., Anne M Walsh, Hoelscher, Michael, Kijak, Gustavo H., Bautista, Christian T, Michael Hoelscher, McCutchan Francine E., Kim, Jerome, Eller Leigh Anne, Koehler, Rebecca N, Merlin L Robb, Bautista, Christian T., Koehler, Rebecca N., Koehler Rebecca N., Sanders-Buell, Eric E, Sanders-Buell Eric E., Walsh, Anne M., Currier, Jeffrey R., Gustavo H Kijak, Walsh Anne M.   +53 more
core   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

A Cluster of Candida auris Blood Stream Infections in a Tertiary Care Hospital in Oman from 2016 to 2019

Antibiotics, 2020
(1) Background: Candida auris has been reported as emerging yeast pathogen that can cause invasive bloodstream infections in healthcare settings. It is associated with high mortality rates and resistance to multiple classes of antifungal drugs and is ...
Jalila Mohsin, Sanjeewani Weerakoon, Sarah Ahmed, Ynze Puts, Zainab Al Balushi, Jacques F. Meis, Abdullah M.S. Al-Hatmi   +6 more
doaj   +1 more source

Population genetic analysis of Plasmodium falciparum parasites using a customized Illumina GoldenGate genotyping assay. [PDF]

, 2011
The diversity in the Plasmodium falciparum genome can be used to explore parasite population dynamics, with practical applications to malaria control.
Abdoulaye Djimde, Newbold, CI, Steven M Kiara, MacInnis, B, Jiang Hongying, Amaratunga, Chanaki, Mangano Valentina, Panos Deloukas, Socheat, Duong, Kirk Rockett, Jiang, H, Kivinen, K, MacInnis Bronwyn, Borrmann Steffen, Kwiatkowski, DP, Kiara Steven M., Kwiatkowski, Dominic, Pascal Michon, Valentina Mangano, Dominic P Kwiatkowski, Kwiatkowski Dominic P., Taane G Clark, Djimde Abdoulaye, Christopher I. Newbold, Borrmann, S, Deloukas, P, Rockett, K, Su, X-Z, Dominic P. Kwiatkowski, Nicholas J White, Imwong, Mallika, Ouedraogo, JB, Anderson, Timothy, Nicholas J. White, White Nicholas J., Zongo Issaka, Campino, S, Taane G. Clark, MacInnis, Bronwyn, Auburn Sarah, Clark, Taane G, Clark, TG, Newbold, Christopher, Nosten, François, Issaka Zongo, Nzila, A, Rockett Kirk, Gwilliam Rhian, Kevin Marsh, Djimde, Abdoulaye, Newbold, Christopher I, Xin-Zhuan Su, Kivinen, Katja, Amaratunga Chanaki, Rhian Gwilliam, Nosten François, Susana Campino, White, Nicholas J, Sarah Auburn, Fairhurst, Rick M, Michon, P, Nzila, Alexis, Gwilliam, Rhian, Mueller, Ivo, Siba, P, Doumbo Ogobara K., Ivo Mueller, Marsh, K, Zongo, Issaka, Chanaki Amaratunga, Timothy Anderson, Christopher I Newbold, Imwong Mallika, Jean-Bosco Ouedraogo, Clark Taane G., Alexis Nzila, Socheat Duong, Imwong, M, Anderson, T, Kiara, SM, White, NJ, Marsh, Kevin, Jean Bosco Ouedraogo, Fairhurst, RM, Steven M. Kiara, Michon, Pascal, Doumbo, Ogobara K, Deloukas, Panos, Marsh Kevin, Su, Xin-Zhuan, Djimde, A, Peter Siba, Siba, Peter, Mueller, I, Mallika Imwong, Ogobara K. Doumbo, Anderson Timothy, Hongying Jiang, White, Nicholas, Gwilliam, R, Katja Kivinen, Kiara, Steven M, Michon Pascal, Mangano, V, Siba Peter, Kivinen Katja, Zongo, I, Mueller Ivo, Campino Susana, Rick M. Fairhurst, Amaratunga, C, Newbold Christopher I., Auburn, Sarah, Xin Zhuan Su, Auburn, S, Rockett, Kirk, Bronwyn Macinnis, Nzila Alexis, Duong Socheat, François Nosten, Nosten, F, Su, XZ, Ouedraogo Jean-Bosco, Ouedraogo, J-B, Ogobara K Doumbo, Campino, Susana, Socheat, D, Jiang, Hongying, Doumbo, OK, Su Xin-Zhuan, Mangano, Valentina, Rick M Fairhurst, Ouedraogo, Jean-Bosco, Fairhurst Rick M., Borrmann, Steffen, Steffen Borrmann, Deloukas Panos, Kwiatkowski, Dominic P   +137 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source