Results 141 to 150 of about 153,555 (331)

Exploring Functionally Enhanced BLP‐Trained Macrophage Subpopulations in S. Aureus Infection: Underlying Mechanisms and Therapeutic Significance

Advanced Science, EarlyView.
BLP‐trained macrophages show augmented resistance to infection, but their mechanisms remain unclear. scRNA‐seq identified 13 BMDM subsets, with two novel anti‐inflammatory/antibacterial subpopulations (C5/C7) emerging post‐BLP training. BLP training activates NRF2, attenuates oxidative stress/ferroptosis, and boosts glycolysis/OXPHOS. Adoptive transfer
Yantong Wan, Yinghao Hong, Xiangjun Ji, Jing Xiang, Jinxi Liu, Lixin Liang, Meng Ren, Wenhan Chen, Tengfei Xu, Zhijie Li, Tieliu Shi, Yong Jiang, Huaping Liang, Jinghua Liu   +13 more
wiley   +1 more source

USING ADVANCED GENETIC TECHNIQUES IN STUDYING COTTON GENOTYPES APPLIED IN BREEDING [PDF]

, 2006
Ahmed Sharaf, D. EI-Kadi, H. Alatwani
openalex   +1 more source

Genotype Screening and Propagation Techniques of Three Selected Medicinal Plant Species for Production of High-Quality Planting Material [PDF]

, 2021
Farah Fazwa Md Ariff, Sures Kumar Muniandi, Norhayati Saffie, Syafiqah Nabilah Samsul Bahari, Zunoliza Abdullah, Ling Sui Kiong, Masitah Mohd Taini, Siti Nur Aisyah Mohd Hashim, Fadzureena Jamaludin, Mohd Zaki Abdullah   +9 more
openalex   +1 more source

RAD21L1 Is Sufficient and Effective for Reprogramming Human Sertoli Cells to Phenotypic Spermatogonial Stem Cells Through DNA Methylation and Essential for Male Fertility

Advanced Science, EarlyView.
RAD21L1 is upregulated in human Sertoli cells to be transited to become spermatogonial stem cells by overexpressing DAZ family three genes. RAD21L1 is sufficient and effective for reprogramming Sertoli cells into human spermatogonial stem cells with high safety through DNA methylation.
Caimei He, Yinghong Cui, Wei Chen, Chunyun Li, Zuping He   +4 more
wiley   +1 more source

A two-step method for identifying photopigment opsin and rhodopsin gene sequences underlying human color vision phenotypes. [PDF]

, 2020
PurposeTo present a detailed, reliable long range-PCR and sequencing (LR-PCR-Seq) procedure to identify human opsin gene sequences for variations in the long wavelength-sensitive (OPN1LW), medium wavelength-sensitive (OPN1MW), short wavelength-sensitive (
Atilano, Shari R, Briscoe, Adriana D, Jameson, Kimberly A, Kenney, M Cristina   +3 more
core   +1 more source

RET Proto-Oncogene Genotyping Using Unlabeled Probes, the Masking Technique, and Amplicon High-Resolution Melting Analysis [PDF]

, 2007
Rebecca L. Margraf, Rong Mao, W. Edward Highsmith, Leonard M. Holtegaard, Carl T. Wittwer   +4 more
openalex   +1 more source

DKK3 Initially Preserves Acinar Integrity Through MEK‐Fos Signaling, but Later Switches to an Oncogenic Role in Pancreatic Cancer

Advanced Science, EarlyView.
In pancreatic cancer, the protein DKK3 is found to play a complex role: it initially slows early tumor growth but later promotes tumor aggressiveness. DKK3 expression evolves during progression and drives cancer severity by orchestrating cellular and molecular signaling pathways.
Dharini Srinivasan, Elodie Roger, Lukas Perkhofer, Eleni Zimmer, Thomas F.E. Barth, Julia P. Mosler, Anna Härle, Stephanie E. Weissinger, Nadine T. Gaisa, Peter Möller, Nico Fischer, Chantal Allgöwer, J.‐Matthias Löhr, Dirk Grimm, Thomas Seufferlein, Stefan Liebau, Ninel Azoitei, Michael K. Melzer, Frank Arnold, Johann Gout, Alexander Kleger   +20 more
wiley   +1 more source

Sequencing vs. amplification for the estimation of allele dosages in sugarcane (Saccharum spp.)

Applications in Plant Sciences
Premise Detecting single‐nucleotide polymorphisms (SNPs) in a cost‐effective way is fundamental in any plant breeding pipeline. Here, we compare three genotyping techniques for their ability to reproduce the allele dosage of SNPs of interest in sugarcane
Hugo Jaimes, Alejandra Londoño, Carolina Saavedra‐Diaz, Jhon Henry Trujillo‐Montenegro, Jershon López‐Gerena, John J. Riascos, Fernando S. Aguilar   +6 more
doaj   +1 more source

Adaptation of fluorescent technique for genotyping with new microsatellite markers in common bean [PDF]

, 2009
Paula Rodrigues Oblessuc, Tatiana de Campos, Juliana Morini Kupper Cardoso, Danilo Augusto Sforça, Renata Moro Baroni, Anete Pereira de Souza, Luciana Lasry Benchimol‐Reis   +6 more
openalex   +1 more source

Advanced Microfluidics for Single Cell‐Based Cancer Research

Advanced Science, EarlyView.
Cutting‐edge microfluidic platforms are transforming single‐cell cancer research. This review highlights advanced technologies, from droplet microfluidics to tumour‐chips, that enable functional and spatial single‐cell analyses. By integrating biosensing, immune components, and patient‐derived materials, these systems offer new insights into tumour ...
Adriana Carneiro, Marta Aranda Palomer, Margarida Esteves, Carolina Rodrigues, José Maria Fernandes, Francisca Oliveira, Alexandra Teixeira, Carlos Honrado, Lorena Dieguez, Sara Abalde‐Cela, Miguel Xavier   +10 more
wiley   +1 more source