Using genotype abundance to improve phylogenetic inference [PDF]
Modern biological techniques enable very dense genetic sampling of unfolding evolutionary histories, and thus frequently sample some genotypes multiple times. This motivates strategies to incorporate genotype abundance information in phylogenetic inference.
arxiv +1 more source
A High-Density Linkage Map of the Ancestral Diploid Strawberry, Fragaria iinumae, Constructed with Single Nucleotide Polymorphism Markers from the IStraw90 Array and Genotyping by Sequencing [PDF]
Fragaria iinumae Makino is recognized as an ancestor of the octoploid strawberry species, which includes the cultivated strawberry, Fragaria ×ananassa Duchesne ex Rozier.
Abebe-Akele, Feseha+8 more
core +3 more sources
Separation of the largest eigenvalues in eigenanalysis of genotype data from discrete subpopulations [PDF]
We present a mathematical model, and the corresponding mathematical analysis, that justifies and quantifies the use of principal component analysis of biallelic genetic marker data for a set of individuals to detect the number of subpopulations represented in the data. We indicate that the power of the technique relies more on the number of individuals
arxiv +1 more source
Validation of a Polymerase Chain Reaction technique for Kidd blood group genotyping [PDF]
The Kidd blood group antigens, Jkª and Jkᵇ , are two of the main surface markers which are found on the membrane of red blood cells. The determination of whether a donor or a recipient has the Jkª and/or the Jkᵇ antigens is crucially important to ...
Borg, Joseph J.+2 more
core +1 more source
Germline genetic variation in prostate susceptibility does not predict outcomes in the chemoprevention trials PCPT and SELECT [PDF]
Background The development of prostate cancer can be influenced by genetic and environmental factors. Numerous germline SNPs influence prostate cancer susceptibility.
Ahmed, M+7 more
core +2 more sources
Application of high-resolution DNA melting for genotyping in lepidopteran non-model species: Ostrinia furnacalis (Crambidae). [PDF]
Development of an ideal marker system facilitates a better understanding of the genetic diversity in lepidopteran non-model organisms, which have abundant species, but relatively limited genomic resources.
FengBo Li+3 more
doaj +1 more source
SHIELD: Secure Haplotype Imputation Employing Local Differential Privacy [PDF]
We introduce Secure Haplotype Imputation Employing Local Differential privacy (SHIELD), a program for accurately estimating the genotype of target samples at markers that are not directly assayed by array-based genotyping platforms while preserving the privacy of donors to public reference panels.
arxiv
Complexity-based speciation and genotype representation for neuroevolution [PDF]
This paper introduces a speciation principle for neuroevolution where evolving networks are grouped into species based on the number of hidden neurons, which is indicative of the complexity of the search space. This speciation principle is indivisibly coupled with a novel genotype representation which is characterised by zero genome redundancy, high ...
arxiv +1 more source
Novel single nucleotide polymorphism-based assay for genotyping Mycobacterium avium subsp. paratuberculosis [PDF]
Typing of Mycobacterium avium subspecies paratuberculosis strains presents a challenge, since they are genetically monomorphic and traditional molecular techniques have limited discriminatory power.
Bryant, Josephine+6 more
core +2 more sources
The genetics of cardiovascular disease [PDF]
Recent advances in genotyping technology and insights into disease mechanisms have increased interest in the genetics of cardiovascular disease. Several candidate genes involved in cardiovascular diseases were identified from studies using animal models,
Abu-Amero+72 more
core +1 more source