Results 201 to 210 of about 250,832 (305)

Surgical removal of a perirectal melanoma through sphincterotomy and rectal wall resection in a horse

open access: yesEquine Veterinary Education, EarlyView.
Summary Melanomas are among the most frequent neoplasms in grey horses. Deep perirectal melanomas, however, are uncommon and challenging to excise due to their proximity to the peritoneal reflection. This report describes the successful standing removal of a large (16 × 8 × 6 cm) perirectal melanoma firmly adherent to the dorsal rectal wall in a 19 ...
R. Becker, C. Koch, M. de Preux
wiley   +1 more source

Unusual presentation of osteomyelitis of the tuber calcanei in a 16‐month‐old gelding

open access: yesEquine Veterinary Education, EarlyView.
Summary A 16‐month‐old Morgan gelding was referred for evaluation of a right hindlimb lameness (grade 4/5, AAEP) accompanied by swelling of the right calcaneal region. Clinical signs had been present for approximately 4 weeks prior to referral.
A. M. Arreola   +3 more
wiley   +1 more source

Abnormal cleavage patterns in equine in vitro‐produced embryos lead to higher early pregnancy loss

open access: yesEquine Veterinary Journal, EarlyView.
Summary Background Despite significant advances, in vitro production (IVP) of equine embryos continues to lack standardised embryo classification criteria and is associated with increased rates of early pregnancy loss compared with in vivo‐derived blastocysts.
Soledad Martin‐Pelaez   +6 more
wiley   +1 more source

Limited roles of the miR‐17‐92 cluster in the regulation of T‐cell apoptosis

open access: yesThe FEBS Journal, EarlyView.
The pro‐apoptotic protein BIM shapes T‐cell survival and function, but how it is regulated remains unclear. In a mouse model lacking direct miR‐17‐92:Bim interactions, we observed a moderate reduction in Th17 CD4+ T cells. BIM levels were modestly increased in double‐positive thymocytes and naive CD8+ T cells, but this did not affect overall T‐cell ...
Katharina Hoppe   +7 more
wiley   +1 more source

Quantitative analysis of DNA‐GATA1 binding alterations linked to hematopoietic disorders

open access: yesThe FEBS Journal, EarlyView.
Native holdup allows the quantitative determination of affinities between full‐length transcription factors and DNA. Mutations in either the protein or the DNA can modulate binding strength, which can be precisely quantified using this approach. Applied to GATA1, it revealed mutations that alter DNA binding.
Boglarka Zambo   +6 more
wiley   +1 more source

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