Results 71 to 80 of about 171,280 (266)

Gentamicin uptake in the chinchilla inner ear [PDF]

, 2007
Studies of transtympanic gentamicin have focused on clinical use and outcomes. This study presents evidence of bilateral uptake and retention of gentamicin in certain inner ear cells and structures following transtympanic gentamicin application.
Hoffer, Michael, Balaban, Carey D, Roehm, Pamela   +2 more
core   +1 more source

Expression, Purification, and Microscopy‐Based Assays for Engineered Recombinant Tyrosinated, Detyrosinated, and Δ2 Human Tubulin

Cytoskeleton, EarlyView.
ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen, Agnieska Szyk, Antonina Roll‐Mecak   +2 more
wiley   +1 more source

Silica–gentamicin nanohybrids: combating antibiotic resistance, bacterial biofilms, and in vivo toxicity [PDF]

, 2018
Dina A Mosselhy,1–3 Wei He,4 Ulla Hynönen,5 Yaping Meng,6 Pezhman Mohammadi,1 Airi Palva,5 Qingling Feng,7 Simo-Pekka Hannula,2 Katrina Nordström,1 Markus B Linder11Department of Bioproducts and Biosystems, School of Chemical Engineering,
Hynönen U, Mohammadi P, He W, Palva A, Hannula SP, Linder MB, Feng QL, Mosselhy DA, Nordström K, Meng Y   +9 more
core  

Silica-gentamicin nanohybrids: Synthesis and antimicrobial action [PDF]

, 2016
Orthopedic applications commonly require the administration of systemic antibiotics. Gentamicin is one of the most commonly used aminoglycosides in the treatment and prophylaxis of infections associated with orthopedic applications, but gentamicin has a ...
Natri, Olli, Yanling Ge, Dina Mosselhy, Hannula, Simo-Pekka, Ahmed Mosselhy, Dina, Gasik, Michael, Michael Gasik, Olli Natri, Simo-Pekka Hannula, Ge, Yanling, Nordström, Katrina, Katrina Nordström   +11 more
core   +1 more source

Surface‐Strongly Complexed BiVO4 Homojunction Photoanodes: Enabling Efficient Antibiotic Pollutant Degradation and Resource Upgrading

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Herein, a synergistic photoelectrochemical‐photothermal platform is constructed for simultaneous kanamycin remediation and resource valorization, addressing energy and environmental concerns. Photoelectrochemical (PEC) technology offers a promising approach for degrading antibiotic pollutants, yet it remains constrained by low efficiency and incomplete
Zhaoqi Wang, Yaqi He, Xiaolei Liu, Zaizhu Lou, Difei Xiao, Peng Wang, Zhaoke Zheng, Yuanyuan Liu, Hefeng Cheng, Baibiao Huang, Zeyan Wang, Dongqi Tang   +11 more
wiley   +1 more source

Methyltransferases of gentamicin biosynthesis [PDF]

, 2018
Gentamicin C complex from Micromonospora echinospora remains a globally important antibiotic, and there is revived interest in the semisynthesis of analogs that might show improved therapeutic properties. The complex consists of five components differing
Anna Reva, Junhong Guo, Yuhui Sun, Fanglu Huang, Sicong Li, Yuanzhen Liu, Zixin Deng, Peter F. Leadlay, Binbin Xiong   +8 more
core   +2 more sources

1‐(Acetylamino)thioxanthones and Derivatives: Synthesis From 1‐Halogenothioxanthones and Biological Properties

European Journal of Organic Chemistry, EarlyView.
The conversion of 1‐halogenothioxanthones into 1‐(acetylamino) derivatives and their NaH‐mediated cyclization have been optimized. This rapid method yields thiochromeno[4,3,2‐de]quinol‐2‐ones that exhibit promising in vitro anticancer activity. Institute and/or researcher Bluesky usernames: https://bsky.app/profile/iscr‐rennes.bsky.social.
Najet Ballagha, Frédéric Lassagne, William Erb, Isabelle Rouaud, Sophie Tomasi, Ziad Fajloun, Mona El Samarji, Mohamad Rima, Anamaria Mendonça Santos, Laurent Picot, Valérie Thiéry, Hédi M’Rabet, Florence Mongin   +12 more
wiley   +1 more source

Piezosurgical partial ostectomy of the incisive bone for an ossifying fibroma removal in a 4‐year‐old Warmblood gelding

Equine Veterinary Journal, EarlyView.
Abstract Background Ossifying fibromas are uncommon in horses and complete surgical excision with premaxillectomy, maxillectomy or mandibulectomy is recommended. Piezosurgery has been previously used in equines only in one study. Objective To report a case of ossifying fibroma treated with piezosurgery and to describe its follow‐up.
G. Forni, M. E. Falomo, I. Casalini, M. Isola   +3 more
wiley   +1 more source

Intratympanic methylprednisolone versus gentamicin in patients with unilateral Ménière's disease: a randomised, double-blind, comparative effectiveness trial [PDF]

, 2016
BACKGROUND: Ménière's disease is characterised by severe vertigo attacks and hearing loss. Intratympanic gentamicin, the standard treatment for refractory Ménière's disease, reduces vertigo, but damages vestibular function and can worsen hearing.
Seemungal, Barry M, Rea, P., Golding, John F, JP Harcourt (7756886), Rea, P, Harcourt, JP, Hariri, M, Agarwal, K, M Patel (7741574), Arshad, Q., Hariri, M., Q Arshad (7718309), Bronstein, Adolfo M, Bronstein, Adolfo M., Rea, Peter, AM Bronstein (7729337), Golding, J.F., P Rea (7756880), Seemungal, B.M., Bronstein, A.M., Agarwal, K., Patel, M, JF Golding (7756883), Harcourt, J.P., BM Seemungal (7738358), Golding, JF, Hariri, Mohamed, Harcourt, Jonny P, Patel, M., Seemungal, BM, Patel, Mitesh, Arshad, Q, Bronstein, AM, Arshad, Qadeer, Agarwal, Kiran, K Agarwal (7756874), M Hariri (7756877)   +36 more
core   +1 more source

Cheek tooth extraction in geriatric versus non‐geriatric horses

Equine Veterinary Journal, EarlyView.
Abstract Background Age‐related dental changes are major contributors to dental disorders in older horses, and cheek tooth extractions are often required to maintain masticatory function and oral comfort. However, limited information is available on clinical and treatment characteristics in this older patient population.
Elias Mair, Omid Nekouei, Patricia Trummer‐Schug, Rhea Haralambus, Nora Mareike Biermann   +4 more
wiley   +1 more source