Color Forming Property of Derivative and Modification Products of Natural Iridoids with Methylamine [PDF]
, 2015 Derivatives and modified products of five natural iridoids (geniposide, gentiopicroside, swertiamarin, loganin and morroniside) were obtained by derivatization or modification.
Ding, Keyi, Liu, Jun, Shao, Xue
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Results in ChemistryThis study describes the extraction efficiency of loganic acid and gentiopicroside from Gentianae radix et rhizoma using the deep eutectic solvent-based ultrasound-assisted extraction (DES-UAE) method.
Xiaolin Tang +4 more
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Virtual Screening of Compounds for the Identification of Potential Drug Candidates Targeting the RACK1 Receptor in Liver Cancer [PDF]
Background: Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths globally and the sixth most common cancer, particularly in the Asia-Pacific and African regions. Liver cirrhosis, a critical precursor to HCC and liver failure,
Aloufi, Bandar Hamad
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Evaluation of Anticonvulsant, Sedative, Anxiolytic, and Phytochemical Profile of the Methanol Extract from the Aerial Parts of Swertia corymbosa (Griseb.) Wight ex C.B. Clarke [PDF]
, 2020 The objective of the present study was to evaluate the anxiolytic, antidepressant, and anticonvulsant activity of the methanolic extract of Swertia corymbosa (SCMeOH). After acute toxicity test, oral treatment with SCMeOH at doses of 125, 250, and 500 mg/
G Mahendran +3 more
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Scientific ReportsThe occurrence of nonenzymatic glycosylation reactions in skin fibroblasts can lead to severe impairment of skin health. To investigate the protective effects of the major functional ingredient from Gentianaceae, gentiopicroside (GPS) on fibroblasts ...
Chunyu Chen +7 more
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Plant Iridoids Affect Intraocular Pressure and Vascular Flow in the Rabbit Eye
Applied SciencesFor plant-derived raw materials, there are very few studies regarding the effect of intraocular administration on intraocular pressure (IOP) and associated blood flow. Traditional folk medicine uses many natural resources for eye disorders.
Dorota Szumny +3 more
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A highly specific O-methyltransferase for nororientaline synthesis isolated from Argemone platyceras cell cultures [PDF]
, 1983 Nagakura, Naotaka +2 more
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Iridoids and flavonoids from the aerial parts of Gentiana asclepiadea L. with anti-inflammatory and analgesic activities [PDF]
, 2023 Barta Anita +5 more
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Antiviral Mechanism of Gentiopicroside Against Herpes Zoster by Targeting TLR3
Acta Poloniae Pharmaceutica - Drug ResearchHerpes zoster (HZ), caused by the reactivation of human herpes virus 3 (HHV-3), is a painful neurological condition with limited treatment options. Gentiopicroside (GPS), a key iridoid compound from the traditional Chinese medicine Gentiana scabra, possesses broad anti-inflammatory and immunomodulatory properties, yet its potential against HHV-3 ...
Yan Zhou, Jinbao Zhong
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Natural Product CommunicationsObjectives Yellow gentian ( Gentiana lutea L., Gentianaceae) has long been valued in traditional medicine primarily as a bitter drug. While recent studies have confirmed its pleiotropic properties, the antineurodegenerative potential of its bioactive ...
Jelena Mudrić +6 more
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