Results 81 to 90 of about 1,328 (198)

The cellular and molecular targets of natural products against metabolic disorders: a translational approach to reach the bedside

MedComm, Volume 5, Issue 8, August 2024.
Metabolic disorders seriously endanger the health of human beings. However, there are no approved drugs specific for metabolic disorders. Recently, sever natural products have been demonstrated to alleviate metabolic disorders, and also used as chemical probes to identify their functional targets, which are involved in insulin resistance, glycolipid ...
Xiaofei Shen, Hongling Yang, Yang Yang, Xianjun Zhu, Qingxiang Sun   +4 more
wiley   +1 more source

Screening of antioxidant activity of Gentian Lutea root and its application in Oil-in-Water Emulsions [PDF]

, 2014
Gentiana Lutea root (G. Lutea) is a medicinal herb, traditionally used as a bitter tonic in gastrointestinal ailments for improving the digestive system. The active principles of G.
Almajano Pablos, María Pilar, Gil Moya, Emilio, Martínez Farré, Francesc Xavier, Mohd Azman, Nurul Aini, Segovia Gómez, Francisco José   +4 more
core   +3 more sources

Quantitative and Qualitative Characterization of Gentiana rigescens Franch (Gentianaceae) on Different Parts and Cultivations Years by HPLC and FTIR Spectroscopy

Journal of Analytical Methods in Chemistry, 2017
Gentiana rigescens Franch (Gentianaceae) is a famous medicinal plant for treatments of rheumatism, convulsion, and jaundice. Comprehensive investigation of different parts and cultivation years of this plant has not yet been conducted.
Lu-Ming Qi, Ji Zhang, Yan-Li Zhao, Zhi-Tian Zuo, Hang Jin, Yuan-Zhong Wang   +5 more
doaj   +1 more source

Low‐Molecular Weight Compounds that Extend the Chronological Lifespan of Yeasts, Saccharomyces cerevisiae, and Schizosaccharomyces pombe

Advanced Biology, Volume 8, Issue 5, May 2024.
Budding and fission yeasts are excellent model organisms for research on aging and lifespan regulation. Chronological lifespan, a definition of yeast lifespan, refers to the survival period of a cell population under nondividing conditions. In this review, the low‐molecular weight compounds are summarized that extend the chronological lifespan of ...
Hokuto Ohtsuka, Takafumi Shimasaki, Hirofumi Aiba   +2 more
wiley   +1 more source

Investigation of a Medical Plant for Hepatic Diseases with Secoiridoids Using HPLC and FT-IR Spectroscopy for a Case of Gentiana rigescens

Molecules, 2020
Secoiridoids could be used as a potential new drug for the treatment of hepatic disease. The content of secoiridoids of G. rigescens varied in different geographical origins and parts.
Yuangui Yang, Yanli Zhao, Zhitian Zuo, Ji Zhang, Yao Shi, Yuanzhong Wang   +5 more
doaj   +1 more source

Drugs targeting CTGF in the treatment of pulmonary fibrosis

Journal of Cellular and Molecular Medicine, Volume 28, Issue 10, May 2024.
Abstract Pulmonary fibrosis represents the final alteration seen in a wide variety of lung disorders characterized by increased fibroblast activity and the accumulation of substantial amounts of extracellular matrix, along with inflammatory damage and the breakdown of tissue architecture.
Yudan Qiu, Yueyue Que, Zheyu Ding, Shanshan Zhang, Rong Wei, Jianing Xia, Yingying Lin   +6 more
wiley   +1 more source

Hot Spots of Bitter Compounds in the Roots of Gentiana lutea L. subsp. aurantiaca: Wild and Cultivated Comparative [PDF]

[EN] Gentiana lutea L. subsp. aurantiaca M. Lainz is a plant endemic to the north-western mountainous areas of the Iberian Peninsula. Its roots are widely used mainly because of the high content of bitter compounds.
0000-0001-9124-4390, 0000-0002-1745-8902, 0000-0002-2117-593X, 0000-0002-4432-9794, 0000-0002-6004-9653, Arbizu-Milagro, Julia, Casquero, Pedro A., González-López, Óscar, Pinto, Carmelo García, Rodríguez-González, Álvaro   +9 more
core   +2 more sources

Chemical composition, antioxidant and antigenotoxic activities of different fractions of Gentiana asclepiadea L. roots extract [PDF]

, 2013
The aim of this study was to evaluate the antioxidant and antigenotoxic activities of chloroform, ethyl acetate and n-butanol fractions obtained from Gentiana asclepiadea L. roots methanolic extract.
Katanić, Jelena, Matić, Sanja, Mihailović, Vladimir, Mišić, Danijela, Mladenović, Milan, Solujić, Slavica, Stanić, Snežana, Stanković, Nevena   +7 more
core  

Quality Assessment of Gentiana rigescens from Different Geographical Origins Using FT-IR Spectroscopy Combined with HPLC

Molecules, 2017
Gentiana rigescens is a precious herbal medicine in China because of its liver-protective and choleretic effects. A method for the qualitative identification and quantitative evaluation of G.
Zhe Wu, Yanli Zhao, Ji Zhang, Yuanzhong Wang   +3 more
doaj   +1 more source

Structural Revision of a Naphthodipyranodione from Gentian Root and its Degradation Pathway from Gentiopicroside

Natural Product Communications, 2017
Based on NOE experiments, the structure of naphthodipyranodione from Gentianaceae plants was revised to 1,2-dihydro-4 H ,6 H ,8 H -naphto[1,2-d:4,5-c'd']dipyrano-4,8-dione.
Mikio Fujii, Hidehiro Ando, Kiju Konno, Motonori Fukumura, Yumiko Hori, Yasuaki Hirai, Yoshiteru Ida   +6 more
doaj   +1 more source