Results 71 to 80 of about 806 (159)

Study of the mechanism by gentiopicroside protects against skin fibroblast glycation damage via the RAGE pathway

Scientific Reports
The occurrence of nonenzymatic glycosylation reactions in skin fibroblasts can lead to severe impairment of skin health. To investigate the protective effects of the major functional ingredient from Gentianaceae, gentiopicroside (GPS) on fibroblasts ...
Chunyu Chen, Xiaoxing Liu, Li Li, Miaomiao Guo, Yifan He, Yinmao Dong, Hong Meng, Fan Yi   +7 more
doaj   +1 more source

Plant Iridoids Affect Intraocular Pressure and Vascular Flow in the Rabbit Eye

Applied Sciences
For plant-derived raw materials, there are very few studies regarding the effect of intraocular administration on intraocular pressure (IOP) and associated blood flow. Traditional folk medicine uses many natural resources for eye disorders.
Dorota Szumny, Tomasz Sozański, Adam Szeląg, Antoni Szumny   +3 more
doaj   +1 more source

Antiviral Mechanism of Gentiopicroside Against Herpes Zoster by Targeting TLR3

Acta Poloniae Pharmaceutica - Drug Research
Herpes zoster (HZ), caused by the reactivation of human herpes virus 3 (HHV-3), is a painful neurological condition with limited treatment options. Gentiopicroside (GPS), a key iridoid compound from the traditional Chinese medicine Gentiana scabra, possesses broad anti-inflammatory and immunomodulatory properties, yet its potential against HHV-3 ...
Yan Zhou, Jinbao Zhong
openaire   +1 more source

<i>Gentiana sino-ornata</i> Balf. f. ethyl acetate extract alleviates high-fat diet- and tetracycline-induced liver injury in mice: insights from serum pharmacochemistry, network pharmacology, and experimental validation. [PDF]

Front Pharmacol
Zhang M, Xia Z, Gu Q, Ye L, Chen C.
europepmc   +1 more source

Quantitative Analysis and Network Pharmacology-Based Profiling of Isolated Metabolites from Swertia purpurascens (D.Don) C.B. Clarke. [PDF]

J Sep Sci
Swati K, Kumar N, Sharma T, Bhatt P, Bhandari P.   +4 more
europepmc   +1 more source

Siweixizangmaoru Decoction Alleviates Rheumatoid Arthritis by Enhancing Pol β-Mediated Attenuation of DNA Damage and Suppression of cGAS/STING/NF-κB/NLRP3-Associated Pyroptosis. [PDF]

Pharmaceuticals (Basel)
Chu X, Chen X, Yuan Y, Niu Y, Zhou W, Cui Y, Pan Y, Liu H, Dongzhi Z, Huang S, Li B.   +10 more
europepmc   +1 more source

Quality Evaluation and Antioxidant Activity of Cultivated <i>Gentiana siphonantha</i>: An Ethnic Medicine from the Tibetan Plateau. [PDF]

Molecules
Li J, Zang L, Song X, Liu Z, Li H, Sun J.   +5 more
europepmc   +1 more source

Editorial: Discovery and function research of novel natural products. [PDF]

Front Chem
Liao P, Chen P, Xu D, Xie F.
europepmc   +1 more source

Metabolomics-transcriptomics analysis reveals the mechanism by which <i>Gentiana lawrencei</i> var. <i>farreri</i> promotes flowering under different diurnal temperatures. [PDF]

Front Plant Sci
Zeren L, Deqing Z, Xu Y, Zhang H, Zhang Y, Deng H, Chen H, Gu R, Chen G.   +8 more
europepmc   +1 more source

Iridoids from Traditional Chinese Medicine for Neuropathic Pain: Therapeutic Potential and Molecular Mechanisms. [PDF]

Drug Des Devel Ther
Wang W, Liu T, Ding Y, Liu X, Qingji R, Zhang Y, Zhang Z.   +6 more
europepmc   +1 more source