Results 51 to 60 of about 806 (159)

Progress on the Protective Effect and the Mechanism of Chinese Medicine Injection and Chinese Medicine Monomeric Small Molecules on Sepsis‐Related Liver Injury

open access: yesGut Medicine, Volume 2, Issue 1, Page 40-57, March 2026.
ABSTRACT Sepsis‐related liver injury (SRLI) involves multiple interrelated pathological processes, including excessive inflammation, oxidative imbalance, mitochondrial dysfunction, dysregulated autophagy, and microcirculatory impairment. Increasing evidence indicates that traditional Chinese medicine (TCM)–based interventions, particularly Chinese ...
Xiang Yunsheng, Yan Yumeng
wiley   +1 more source

Allelopathic Sugarcane Leaf Litter and Its Potential Use as Soil Mulching for Weed Management in Sugarcane Cultivation

open access: yesWeed Research, Volume 66, Issue 1, January/February 2026.
ABSTRACT Sugarcane leaves, both green and fallen, left after harvest, are agricultural residues containing compounds that inhibit weed germination and seedling growth. This study evaluated their allelopathic effects and mulching potential for weed control.
Ramida Krumsri   +4 more
wiley   +1 more source

Marine‐Derived Biomaterials in Psoriasis Treatment: Therapeutic Potential and Development Perspectives

open access: yesDermatologic Therapy, Volume 2026, Issue 1, 2026.
Psoriasis is a multifactorial skin disease characterized by inflamed, scaly lesions arising from abnormal keratinocytes proliferation and immune dysregulation. Its persistent and relapsing nature underscores the need for long‐term treatment, making natural products increasingly attractive as alternative therapeutic options.
Tri Purwa Ningrum   +9 more
wiley   +1 more source

Ubiquitination in cancer: mechanisms and therapeutic opportunities

open access: yesCancer Communications, Volume 45, Issue 9, Page 1128-1161, September 2025.
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu   +7 more
wiley   +1 more source

Bioactivities of Centaurium erythraea (Gentianaceae) Decoctions: Antioxidant Activity, Enzyme Inhibition and Docking Studies

open access: yesMolecules, 2019
Centaurium erythraea is recommended for the treatment of gastrointestinal disorders and to reduce hypercholesterolemia in ethno-medicinal practice. To perform a top-down study that could give some insight into the molecular basis of these bioactivities ...
Laura Guedes   +5 more
doaj   +1 more source

Epithelial–Mesenchymal Transition in Cancer: Insights Into Therapeutic Targets and Clinical Implications

open access: yesMedComm, Volume 6, Issue 9, September 2025.
This graphical abstract summarizes the effects of ionizing radiation (IR) on epithelial–mesenchymal transition (EMT), emphasizing critical processes such as DNA damage repair, tumor microenvironment interactions, and resistance mechanisms. It highlights EMT‐induced radioresistance regulators, such as TGF‐β, Wnt, Notch, ERK, and various miRNAs, as well ...
Dhasarathdev Srinivasan   +7 more
wiley   +1 more source

Butyrate alleviates food allergy by improving intestinal barrier integrity through suppressing oxidative stress‐mediated Notch signaling

open access: yesiMeta, Volume 4, Issue 3, June 2025.
Compared to healthy controls, children with food‐sensitized tolerance and food allergy showed reduced fecal short‐chain fatty acids (SCFAs), particularly butyrate. In an ovalbumin‐sensitized mouse model, butyrate outperformed other SCFAs in alleviating allergic responses.
Jialu Shi   +11 more
wiley   +1 more source

Assessment of the Nutraceutical Properties of Wild Strawberry (Fragaria vesca L.) Extracts on Human Colorectal Cell Lines

open access: yesMolecular Nutrition &Food Research, Volume 69, Issue 11, June 2025.
The study explores the nutraceutical potential of wild strawberry (Fragaria vesca L.) by assessing its effects on multiple colorectal carcinoma cell lines. Wild strawberry phytochemicals were able to reduce SW480 cell viability by inducing cell cycle arrest and by promoting programmed cell death in E705 cells, with no toxicity on healthy colorectal ...
Monica Oldani   +7 more
wiley   +1 more source

Determination and Pharmacokinetic Study of Gentiopicroside, Geniposide, Baicalin, and Swertiamarin in Chinese Herbal Formulae after Oral Administration in Rats by LC-MS/MS

open access: yesMolecules, 2014
A sensitive and efficient liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed for the simultaneous determination of gentiopicroside, geniposide, baicalin, and swertiamarin in rat plasma. To avoid the stress caused by restraint
Chia-Ming Lu   +2 more
doaj   +1 more source

Anti‐Glycation and Anti‐Aging Efficacy of Newly Synthesized Antioxidant With Autophagy Stimulating Activity

open access: yesJournal of Cosmetic Dermatology, Volume 24, Issue 5, May 2025.
ABSTRACT Background The accumulation of advanced glycation end products (AGEs) in aged skin and their pro‐aging effects suggest the potential application of anti‐glycation ingredients as skin anti‐aging agents. Aims This study evaluated the anti‐aging efficacy of a newly developed anti‐glycation ingredient with antioxidant and autophagy‐stimulating ...
Kayoung Shin   +7 more
wiley   +1 more source

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