Pharmaceuticals, 2023 The objective of the present study was to develop a gentiopicroside-phospholipid complex (GTP-PC) and its self-nanoemulsion drug delivery system (GTP-PC-SNEDDS) to increase the oral bioavailability of gentiopicroside (GTP).
Yingpeng Tong +3 more
doaj +1 more source
In vitro propagation of Gentiana scabra Bunge – an important medicinal plant in the Chinese system of medicines [PDF]
, 2014 Background: Gentiana scabra Bunge commonly known as `Long dan cao\u27 in China has been used in traditional Chinese medicines for more than 2000 years.
Agrawal, Dinesh Chandra +3 more
core +2 more sources
Microbial Biotransformation of Gentiopicroside by the Endophytic Fungus Penicillium crustosum 2T01Y01 [PDF]
Applied and Environmental Microbiology, 2014 ABSTRACT Endophytic fungi are symbiotic with plants and possess multienzyme systems showing promising metabolite potency with region selectivity and stereoselectivity. The aim of this study was to use these special microorganisms as an in vitro model to mimic the potential mammalian metabolites of a ...
Wen-Liang, Zeng +6 more
openaire +2 more sources
Guangxi Zhiwu, 2023 Gentiana macrophylla is a traditional Chinese herbal medicine for treating jaundice, hepatitis, and stomachic and choleretic ailments, and its main secondary metabolites are secoiridiod glycosides represented by gentiopicroside.
Huanhuan FU +5 more
doaj +1 more source
The distribution, uses, and characteristic components of gentianaceae plants in China
World Journal of Traditional Chinese Medicine, 2021 Extracts of Gentianaceae herbs have been widely used as food additives, teas, or medicinal remedies for various human diseases and disorders. Iridoids, secoiridoids, and analogs glycosides, mainly include gentiopicroside, sweroside, swertiamarin, and ...
Han Cheng +5 more
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Biotechnology & Biotechnological Equipment, 2016 To obtain an alternative source for the production of gentiopicroside, here genomic DNA segments of the medicinal plant Gentiana macrophylla were randomly transferred into Hansenula polymorpha by 25 KeV nitrogen ions (N+) at a dose of 2.5 × 1016 ions/cm2
Ting Wang +4 more
doaj +1 more source
Frontiers in Pharmacology, 2020 Rheumatoid arthritis (RA) is among the most prevalent forms of autoimmunity. Gentiopicroside (Gent) is an iridoid glucoside derived from the Gentiana Macrophylla Pall which is used in traditional Chinese medicine to treat RA.
Meiling Wang +10 more
doaj +1 more source
In vitro propagation and analysis of secondary metabolites in Glossogyne tenuifolia (Hsiang-Ju) - a medicinal plant native to Taiwan [PDF]
, 2014 Background Glossogyne tenuifolia Cassini (Hsiang-Ju in Chinese) is a perennial herb native to Penghu Islands, Taiwan. The herb is a traditional anti-pyretic and hepatoprotective used in Chinese medicine.
Chao-Lin Kuo +5 more
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Protection of lethal toxicity of endotoxin by Salvia miltiorrhiza BUNGE is via reduction in tumor necrosis factor alpha release and liver injury [PDF]
, 2006 Lipopolysaccharide (LPS) has been implicated as one of the major cause of Gram-negative bacteria-induced sepsis that are life-threatening syndromes occurring in intensive care unit patients. Many natural products derived from medicinal plants may contain
Chan, DKO +4 more
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Comprehensive metabolite profiling of Plantaginis Semen using ultra high performance liquid chromatography with electrospray ionization quadrupole time-of-flight tandem mass spectrometry coupled with elevated energy technique [PDF]
, 2016 Plantaginis Semen is commonly used in traditional medicine to treat edema, hypertension, and diabetes. The commercially available Plantaginis Semen in China mainly comes from three species.
Bateman +48 more
core +1 more source