Results 41 to 50 of about 1,328 (198)

Development of gastroretentive floating granules with gentian root extract by hot-melt granulation [PDF]

open access: yes, 2020
The roots of yellow gentian, Gentiana lutea L. (Gentianaceae) are used in traditional medicine for the treatment of gastrointestinal disorders, with the literature data indicate a local gastric effect of gentian root extract (GRE) and support the use of ...
Bigović, Dubravka***dbigovic@mocbilja.rs***Institute for Medicinal Plants Research “Dr. Josif Pančić”, Tadeuša Košćuška 1, 11000 Belgrade, Serbia***   +3 more
core   +2 more sources

Iridoids of fenugreek (Trigonella-foenum-graecum L.) seed extract detected via LC-QTOF-MS analysis

open access: yesFuture Foods, 2021
Fenugreek seed is a traditional medicinal plant with a wide biological activity. In this study, iridoids (Asperulosidic acid (1), 7-O-Methylmorroniside (2), Gentiopicroside (3), Rehmannioside A (4), Loganic acid-6′-O-β-Dglucoside (5), Sweroside (6 ...
Sweeta Akbari   +3 more
doaj   +1 more source

Safety of a feed additive consisting of a tincture derived from the roots of Gentiana lutea L. (gentian tincture) for all animal species (FEFANA asbl)

open access: yesEFSA Journal, 2023
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety of a tincture derived from Gentiana lutea L. (gentian tincture). It is intended to be used as a sensory additive for all animal species.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)   +22 more
doaj   +1 more source

Metabolism of gentiopicroside (gentiopicrin) by human intestinal bacteria.

open access: yesChemical and Pharmaceutical Bulletin, 1989
As a part of our studies on the metabolism of crude drug components by intestinal bacteria, gentiopicroside (a secoiridoid glucoside isolated from Gentiana lutea), was anaerobically incubated with various defined strains of human intestinal bacteria. Many species had ability to transform it to a series of metabolites. Among them, Veillonella parvula ss
A I, el-Sedawy   +3 more
openaire   +3 more sources

Schisandrol A Exhibits Estrogenic Activity via Estrogen Receptor α-Dependent Signaling Pathway in Estrogen Receptor-Positive Breast Cancer Cells

open access: yesPharmaceutics, 2021
The aim of this study was to examine the estrogen-like effects of gentiopicroside, macelignan, γ-mangostin, and three lignans (schisandrol A, schisandrol B, and schisandrin C), and their possible mechanism of action. Their effects on the proliferation of
Dahae Lee   +3 more
doaj   +1 more source

Gentiopicroside-Loaded Chitosan Nanoparticles Inhibit TNF-α-Induced Proliferation and Inflammatory Response in HaCaT Keratinocytes and Ameliorate Imiquimod-Induced Dermatitis Lesions in Mice

open access: yesInternational Journal of Nanomedicine, 2023
Kaixuan Zhao,1,* Siqi Pu,2,* Liyun Sun,1 Dongmei Zhou1 1Dermatology Department, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, 10010, People’s Republic of China; 2School of Clinical Medicine, Beijing ...
Zhao K, Pu S, Sun L, Zhou D
doaj  

The secoiridoid glycoside Gentiopicroside is a USP22 inhibitor with potent antitumor immunotherapeutic activity. [PDF]

open access: yesBiomed Pharmacother
Over the past decade, immunotherapies have brought about significant changes in how we approach the treatment of various solid tumors and blood-related cancers. However, the effectiveness of checkpoint blockade therapy has been constrained to a rate of under 30 %. A significant challenge in the realm of tumor immunotherapy revolves around comprehending
Lu W, Chu P, Tang A, Si L, Fang D.
europepmc   +3 more sources

Hepatoprotective properties of Gentiana SPP: Against non-alcoholic fatty liver disease (NAFLD) [PDF]

open access: yes, 2018
Non-alcoholic fatty liver disease (NAFLD) is a metabolic disease characterised by the accumulation of fat in the liver. It is estimated that 33 % of the UK population have NAFLD with 2-5 % progressing to non-alcoholic steatohepatitis (NASH).
Boateng, A., Boateng, A.
core  

Anti‐Lipogenic Effects of Iridoid‐Rich Lonicera caerulea Berry Extracts in a Cortisol‐Stimulated Adipocyte Model

open access: yesJournal of Food Science, Volume 91, Issue 4, April 2026.
ABSTRACT Berries of Lonicera caerulea (blue honeysuckle; haskap) have been used since ancient times in traditional medicine in China, Japan, and northern Russia. This study aimed to extract, characterize, and evaluate the biological activity of iridoid‐rich fractions from haskap berries using an in vitro adipocyte model.
Liangchuan Guo   +5 more
wiley   +1 more source

Comprehensive Quality Assessment Based Specific Chemical Profiles for Geographic and Tissue Variation in Gentiana rigescens Using HPLC and FTIR Method Combined with Principal Component Analysis

open access: yesFrontiers in Chemistry, 2017
Roots, stems, leaves, and flowers of Longdan (Gentiana rigescens Franch. ex Hemsl) were collected from six geographic origins of Yunnan Province (n = 240) to implement the quality assessment based on contents of gentiopicroside, loganic acid, sweroside ...
Jie Li   +5 more
doaj   +1 more source

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