Results 41 to 50 of about 1,328 (198)
Development of gastroretentive floating granules with gentian root extract by hot-melt granulation [PDF]
The roots of yellow gentian, Gentiana lutea L. (Gentianaceae) are used in traditional medicine for the treatment of gastrointestinal disorders, with the literature data indicate a local gastric effect of gentian root extract (GRE) and support the use of ...
Bigović, Dubravka***dbigovic@mocbilja.rs***Institute for Medicinal Plants Research “Dr. Josif Pančić”, Tadeuša Košćuška 1, 11000 Belgrade, Serbia*** +3 more
core +2 more sources
Iridoids of fenugreek (Trigonella-foenum-graecum L.) seed extract detected via LC-QTOF-MS analysis
Fenugreek seed is a traditional medicinal plant with a wide biological activity. In this study, iridoids (Asperulosidic acid (1), 7-O-Methylmorroniside (2), Gentiopicroside (3), Rehmannioside A (4), Loganic acid-6′-O-β-Dglucoside (5), Sweroside (6 ...
Sweeta Akbari +3 more
doaj +1 more source
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety of a tincture derived from Gentiana lutea L. (gentian tincture). It is intended to be used as a sensory additive for all animal species.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +22 more
doaj +1 more source
Metabolism of gentiopicroside (gentiopicrin) by human intestinal bacteria.
As a part of our studies on the metabolism of crude drug components by intestinal bacteria, gentiopicroside (a secoiridoid glucoside isolated from Gentiana lutea), was anaerobically incubated with various defined strains of human intestinal bacteria. Many species had ability to transform it to a series of metabolites. Among them, Veillonella parvula ss
A I, el-Sedawy +3 more
openaire +3 more sources
The aim of this study was to examine the estrogen-like effects of gentiopicroside, macelignan, γ-mangostin, and three lignans (schisandrol A, schisandrol B, and schisandrin C), and their possible mechanism of action. Their effects on the proliferation of
Dahae Lee +3 more
doaj +1 more source
Kaixuan Zhao,1,* Siqi Pu,2,* Liyun Sun,1 Dongmei Zhou1 1Dermatology Department, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, 10010, People’s Republic of China; 2School of Clinical Medicine, Beijing ...
Zhao K, Pu S, Sun L, Zhou D
doaj
The secoiridoid glycoside Gentiopicroside is a USP22 inhibitor with potent antitumor immunotherapeutic activity. [PDF]
Over the past decade, immunotherapies have brought about significant changes in how we approach the treatment of various solid tumors and blood-related cancers. However, the effectiveness of checkpoint blockade therapy has been constrained to a rate of under 30 %. A significant challenge in the realm of tumor immunotherapy revolves around comprehending
Lu W, Chu P, Tang A, Si L, Fang D.
europepmc +3 more sources
Hepatoprotective properties of Gentiana SPP: Against non-alcoholic fatty liver disease (NAFLD) [PDF]
Non-alcoholic fatty liver disease (NAFLD) is a metabolic disease characterised by the accumulation of fat in the liver. It is estimated that 33 % of the UK population have NAFLD with 2-5 % progressing to non-alcoholic steatohepatitis (NASH).
Boateng, A., Boateng, A.
core
ABSTRACT Berries of Lonicera caerulea (blue honeysuckle; haskap) have been used since ancient times in traditional medicine in China, Japan, and northern Russia. This study aimed to extract, characterize, and evaluate the biological activity of iridoid‐rich fractions from haskap berries using an in vitro adipocyte model.
Liangchuan Guo +5 more
wiley +1 more source
Roots, stems, leaves, and flowers of Longdan (Gentiana rigescens Franch. ex Hemsl) were collected from six geographic origins of Yunnan Province (n = 240) to implement the quality assessment based on contents of gentiopicroside, loganic acid, sweroside ...
Jie Li +5 more
doaj +1 more source

