Results 61 to 70 of about 1,328 (198)

Cornus mas and Cornus Officinalis—Analogies and Differences of Two Medicinal Plants Traditionally Used [PDF]

, 2018
Among 65 species belonging to the genus Cornus only two, Cornus mas L. and Cornus officinalis Sieb. et Zucc. (Cornaceae), have been traditionally used since ancient times.
Czerwińska, Monika E., Melzig, Matthias F.   +1 more
core   +1 more source

Assessment of the Nutraceutical Properties of Wild Strawberry (Fragaria vesca L.) Extracts on Human Colorectal Cell Lines

Molecular Nutrition &Food Research, Volume 69, Issue 11, June 2025.
The study explores the nutraceutical potential of wild strawberry (Fragaria vesca L.) by assessing its effects on multiple colorectal carcinoma cell lines. Wild strawberry phytochemicals were able to reduce SW480 cell viability by inducing cell cycle arrest and by promoting programmed cell death in E705 cells, with no toxicity on healthy colorectal ...
Monica Oldani, Lorenzo Guzzetti, Emiliano Pioltelli, Davide Sala, Davide Panzeri, Maura Brioschi, Matilde Forcella, Paola Fusi   +7 more
wiley   +1 more source

Gentiopicrin exerts anticancer effect on human colon cancer cells via caspase-dependent apoptosis, cell cycle arrest, and inhibition of cell migration and invasion [PDF]

, 2022
Purpose: To investigate the anticancer effect of gentiopicrin on human colon cancer (HT-295) cells, and its effects on caspase-mediated cellular apoptosis, cell cycle, cell migration and cell invasion. Methods: MTT assay and clonogenic assay were used to
Yu, Chenyuan, Zhang, Shaoyu, Zhang, Zheng   +2 more
core   +2 more sources

Anti‐Glycation and Anti‐Aging Efficacy of Newly Synthesized Antioxidant With Autophagy Stimulating Activity

Journal of Cosmetic Dermatology, Volume 24, Issue 5, May 2025.
ABSTRACT Background The accumulation of advanced glycation end products (AGEs) in aged skin and their pro‐aging effects suggest the potential application of anti‐glycation ingredients as skin anti‐aging agents. Aims This study evaluated the anti‐aging efficacy of a newly developed anti‐glycation ingredient with antioxidant and autophagy‐stimulating ...
Kayoung Shin, Yeonjae Kim, Sungwoo Kim, Hyun Jung Kim, Sekyoo Jeong, Mi Jang, Jeong Ho Park, Gaewon Nam   +7 more
wiley   +1 more source

Non‐clinical safety evaluation of Yongdamsagan‐tang water extract: A 13‐week subchronic oral toxicity study in Sprague Dawley rats

Journal of Applied Toxicology, Volume 45, Issue 2, Page 322-338, February 2025.
Abstract Despite the continued clinical application of traditional herbal medicines, scientific evidence such as toxicological safety profile of Yongdamsagan‐tang water extract (YSTW) has not yet been established. The purpose of this study was to investigate the potential toxicity profile of YSTW following a 13‐week repeated oral administration at ...
Woo‐Young Jeon, Chang‐Seob Seo, Hyekyung Ha, Hyeun‐Kyoo Shin, Jae‐Woo Cho, Mee‐Young Lee   +5 more
wiley   +1 more source

Evaluation of neuritogenic activity of cultivated, wild and commercial roots of Gentiana lutea L. [PDF]

, 2015
Several natural products have been proven to prevent neurodegenerative disorders by potentiating the action of nerve growth factor (NGF). Among them, secoiridoids have recently attracted interest for their potential use as neuritogenic compounds.
Caprioli, Giovanni, Dikmen, Miris, Kaya, Elif, Maggi, Filippo, Mustafa, Ahmed M., Sagratini, Gianni, Vittori, Sauro, Öztürk, Yusuf   +7 more
core   +1 more source

A Highly Efficient and User‐Friendly Sensitive Skin Model on the Forearm

Journal of Cosmetic Dermatology, Volume 24, Issue 1, January 2025.
ABSTRACT Background Sensitive skin is a worldwide skin problem, and its assessment of therapeutic efficacy traditionally relies on the facial stinging test. However, this test possesses certain limitations due to its restrictive application site, intense pain sensation, and adverse effects on physical appearance.
Jianhua Zhang, Shichao Liu, Wenjiao Guo, Na Li, Yun Huang   +4 more
wiley   +1 more source

Determination and Pharmacokinetic Study of Gentiopicroside, Geniposide, Baicalin, and Swertiamarin in Chinese Herbal Formulae after Oral Administration in Rats by LC-MS/MS

Molecules, 2014
A sensitive and efficient liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed for the simultaneous determination of gentiopicroside, geniposide, baicalin, and swertiamarin in rat plasma. To avoid the stress caused by restraint
Chia-Ming Lu, Lie-Chwen Lin, Tung-Hu Tsai   +2 more
doaj   +1 more source

Herbal Amara extract induces gastric fundus relaxation via inhibition of the M2 muscarinic receptor

Neurogastroenterology &Motility, Volume 37, Issue 1, January 2025.
This preclinical study demonstrates the relaxant effect of Amara herbal extract (containing nine different plant extracts) on fundus smooth muscles dissected from guinea pigs. This relaxant effect occurs via inhibition of M2 muscarinic receptor activity.
Maria‐Riera Piqué‐Borràs, Johann Röhrl, Gerald Künstle   +2 more
wiley   +1 more source

Analysis of endophyte diversity of two Gentiana plants species and the association with secondary metabolite

BMC Microbiology, 2022
Background The influence of external environmental factors on secondary metabolites of medicinal plants has always been studied. However, little is known about the relationships between endophytes and host metabolites, especially the relationship ...
Qin Zheng Hou, Da Wei Chen, Yu Pei Wang, Nurbiye Ehmet, Jing Ma, Kun Sun   +5 more
doaj   +1 more source