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Changes of Gentiopicroside Synthesis during Somatic Embryogenesis inGentiana macrophylla
Planta Medica, 2009IN VITRO plant regeneration of Gentiana macrophylla Pall. and determination of gentiopicroside content during somatic embryogenesis are described in the present work. The highest percentage of embryogenic callus formation was observed in Murashige and Skoog (MS) medium supplemented with 1.0 mg/L 2,4-dichlorophenoxyacetic acid (2,4-D) and 1.0 mg/L 6 ...
Chen, Li-Yu +5 more
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[Studies on the metabolism of gentiopicroside by rat intestinal flora].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2003To study the metabolism of gentiopicroside by rat intestinal flora in vitro and time profiles of gentiopicroside and its metabolites in rat serum after oral administration of gentiopicroside.Using high performance liquid chromatography (HPLC) for determination of gentiopicroside, gentianine and gentianal content of rat intestinal flora culture medium ...
X F, Yang, C Q, Song
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[Content of gentiopicroside and loganic acid in Radix gentianae and their fingerprints].
Yao xue xue bao = Acta pharmaceutica Sinica, 2009To develop a HPLC-DAD-ESI-TOF/MS analysis method for the determination of gentiopicroside and loganic acid in Radix gentianae samples and for the research of their fingerprints. The samples were extracted using ASE for 10 min under 100 degrees C and 9.65 MPa, and divided into water phase and chloroform phase and analyzed them with HPLC-DAD-ESI-TOF/MS ...
Wen-Long, Li +6 more
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[Callus cultivation and determination of gentiopicroside from Gentiana macrophylla].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2013To explore and improve the utilization efficiency of Gentiana macrophylla resources.The germination of Gentiona macrophylla seeds were used as explants to induce calluses; Cultured on various culture media and condition for callus induction and subculture by test; The content of gentiopicroside in callus was determined by HPLC.The optimum medium for ...
Qian, Hou +4 more
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Gentiopicroside ameliorates glucose and lipid metabolism in T2DM via targeting FGFR1
PhytomedicineThe suppression of the fibroblast growth factor 21/fibroblast growth factor receptor 1 (FGF21/FGFR1) signaling pathway is considered as a vital factor in the type 2 diabetes mellitus (T2DM) progression. Our previous study showed that gentiopicroside (GPS), the main active compound present in Gentiana macrophylla Pall., has the capacity to control ...
Zhanchi, Xu +9 more
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Biosynthesis of Gentiopicroside, a Novel Monoterpene
Journal of the American Chemical Society, 1967C J, Coscia, R, Guarnaccia
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Gentiopicroside attenuates lupus arthritis by targeting galectin-mediated macrophage activation
PhytomedicineInflammatory arthritis represents a common and clinically challenging manifestation of systemic lupus erythematosus (SLE), with current therapeutic options often exhibiting limited efficacy.This study aimed to investigate the anti-arthritic effects and underlying mechanism of gentiopicroside (GPS), a key bioactive constituent of the Jiawei Baihu Jia ...
Yihong Gan +14 more
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In Vitro Transformations of Gentiopicroside and Swertiamarin
Journal of Natural Products, 1988S S, Popov, N L, Marekov, T N, Do
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Fungitoxic Activity of the Secoiridoid Glucoside Gentiopicrin (Gentiopicroside)
Planta Medica, 1981W G, van der Sluis, R P, Labadie
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