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Geographic Atrophy in Age-Related Macular Degeneration. [PDF]
Dtsch Arztebl IntAge-related macular degeneration (AMD), a condition of multifactorial origin, is a major cause of irreversible vision loss in industrialized countries. The dry late stage of the disease, known as geographic atrophy (GA), is characterized by progressive loss of photoreceptor cells and retinal pigment epithelial cells in the central retina.
Liakopoulos S +4 more
europepmc +4 more sources
JAMA Ophthalmology, 2014 Geographic atrophy (GA) is the major cause of blind registration in Western communities, although, with few exceptions, it is less common than choroidal neovascular disease. The variation of phenotype implies that age-related macular degeneration (AMD) does not follow the same course from one case to another and that phenotyping may be important before
Alan C, Bird +2 more
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Geographic Atrophy in Age-Related Macular Degeneration
Ophthalmology Science, 2023 Purpose: To examine disease progression in age-related macular degeneration (AMD) at 2 distinct stages, progression to geographic atrophy (GA) versus GA expansion, by comparison of the risk and protective factors at each stage.
Tiarnan D.L. Keenan, BM BCh, PhD
doaj +1 more source
Geographic atrophy: pathophysiology and current therapeutic strategies
Frontiers in Ophthalmology, 2023 Geographic atrophy (GA) is an advanced stage of age-related macular degeneration (AMD) that leads to gradual and permanent vision loss. GA is characterized by the loss of photoreceptor cells and retinal pigment epithelium (RPE), leading to distinct ...
Kalpana Rajanala +2 more
doaj +1 more source
αA crystallin may protect against geographic atrophy-meta-analysis of cataract vs. cataract surgery for geographic atrophy and experimental studies. [PDF]
PLoS ONE, 2012 BACKGROUND: Cataract and geographic atrophy (GA, also called advanced "dry" age-related macular degeneration) are the two major causes of visual impairment in the developed world.
Peng Zhou +9 more
doaj +1 more source
Geographic atrophy of the macula
Delta Journal of Ophthalmology, 2015 Geographic atrophy of the macula is a late form of dry AMD. Changes found on optical coherence tomography imaging (OCT) include Retinal Pigment Epithelium (RPE) atrophic changes and window defects, with a pronounced photorecetor layer damage.
Alaa M Fadel
doaj +1 more source
Ophthalmology Science, 2022 Purpose: To compare the accuracies of the previously proposed square-root-transformed and perimeter-adjusted metrics for estimating length-type geographic atrophy (GA) growth rates. Design: Cross-sectional and simulation-based study. Participants: Thirty-
Eric M. Moult, PhD +7 more
doaj +1 more source
Retina, 2016 There is a lack of agreement regarding the types of lesions and clinical conditions that should be included in the term "geographic atrophy." Varied and conflicting views prevail throughout the literature and are currently used by retinal experts and other health care professionals.We reviewed the nominal definition of the term "geographic atrophy" and
S. Schmitz-Valckenberg +5 more
openaire +3 more sources
Türk Oftalmoloji Dergisi, 2018 Choroidal neovascularization due to age-related macular degeneration (AMD) is currently treated successfully with anti-vascular endothelial growth factor (VEGF) intravitreal agents.
Süleyman Kaynak +2 more
doaj +1 more source
Serum lipids in adults with late age-related macular degeneration: a case-control study
Lipids in Health and Disease, 2019 Background Lipids are implicated in the pathogenesis of age-related macular degeneration (AMD). The relationship between systemic lipids and AMD has not been well characterized.
Richard D. Semba +12 more
doaj +1 more source