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Germ Cells and Somatic Cells [PDF]
The American Naturalist, 1915 1. It is shown that evidence similar to that which makes probable the potential immortality of protozoa and germ cells also exists in the case of somatic cells of metazoa. As far as the protozoa are concerned, the discussion does not, as seems to be assumed, concern their potential immortality so much as the question whether protozoa correspond to germ
Leo Loeb
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Functional analysis of the Drosophila embryonic germ cell transcriptome by RNA interference. [PDF]
PLoS ONE, 2014 In Drosophila melanogaster, primordial germ cells are specified at the posterior pole of the very early embryo. This process is regulated by the posterior localized germ plasm that contains a large number of RNAs of maternal origin.
Ferenc Jankovics +6 more
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Evidence against a germ plasm in the milkweed bug Oncopeltus fasciatus, a hemimetabolous insect [PDF]
Biology Open, 2013 Summary Primordial germ cell (PGC) formation in holometabolous insects like Drosophila melanogaster relies on maternally synthesised germ cell determinants that are asymmetrically localised to the oocyte posterior cortex.
Ben Ewen-Campen +2 more
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To Be or Not to Be a Germ Cell: The Extragonadal Germ Cell Tumor Paradigm [PDF]
International Journal of Molecular Sciences, 2021 In the human embryo, the genetic program that orchestrates germ cell specification involves the activation of epigenetic and transcriptional mechanisms that make the germline a unique cell population continuously poised between germness and pluripotency. Germ cell tumors, neoplasias originating from fetal or neonatal germ cells, maintain such dichotomy
Massimo De Felici +5 more
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Spermatocytic tumor – case report [PDF]
Liječnički vjesnik, 2021 According to the newest WHO classification tumors of the testis are divided into germ cell tumors derived from germ cell neoplasia in situ, germ cell tumors unrelated to germ cell neoplasia in situ, sex cord-stromal tumors, tumors containing both germ ...
Tonći Vodopić +5 more
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In vitro production of viable eggs from isolated mouse primary follicles by successive culture
The Journal of Reproduction and Development, 2021 To produce viable eggs from single primary follicles in vitro, primary follicles containing oocytes (average 39.0 ± 0.2 µm in diameter) were isolated from the ovaries of 1-week-old mice, and cultured in combination with culture membranes for the first 8 ...
Tomohiro KOHAMA +3 more
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Communications Biology, 2022 High temperatures lead to DNA double-strand break accumulation and asynapsis that trigger the meiotic checkpoint and apoptosis of spermatocytes in ex vivo cultures, providing a rationale for the heat sensitivity of sperm production in mammals.
Kodai Hirano +7 more
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Frontiers in Cell and Developmental Biology, 2018 Germ cell research in vertebrates has traditionally been challenging, but recent breakthroughs have overcome technical difficulties, demonstrating and expanding the power of the zebrafish experimental system for their analysis in vivo. Exploiting the transparency of the zebrafish embryo, germ cell migration was the first topic that moved the germ cells
Roland Dosch, Roland Dosch
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Rat PRDM9 shapes recombination landscapes, duration of meiosis, gametogenesis, and age of fertility
BMC Biology, 2021 Background Vertebrate meiotic recombination events are concentrated in regions (hotspots) that display open chromatin marks, such as trimethylation of lysines 4 and 36 of histone 3 (H3K4me3 and H3K36me3).
Ondrej Mihola +17 more
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Synchronous Primary Parosteal Osteosarcoma and Primary Mediastinal Germ Cell Tumour with Atypical Mycobacterial Infection – A Rare Phenomenon: A Case Report [PDF]
Malaysian Orthopaedic Journal, 2023 Mediastinal germ cell tumours are a rare group of extragonadal germ cell tumours with less than 5% prevalence of all germ cell tumours. Primary mediastinal germ cell tumours themselves account for 16-36% of the extragonadal germ cell tumours. Along the
Lim CH +4 more
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