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In vitro production of viable eggs from isolated mouse primary follicles by successive culture

open access: yesThe Journal of Reproduction and Development, 2021
To produce viable eggs from single primary follicles in vitro, primary follicles containing oocytes (average 39.0 ± 0.2 µm in diameter) were isolated from the ovaries of 1-week-old mice, and cultured in combination with culture membranes for the first 8 ...
Tomohiro KOHAMA   +3 more
doaj   +1 more source

Spermatocytic tumor – case report [PDF]

open access: yesLiječnički vjesnik, 2021
According to the newest WHO classification tumors of the testis are divided into germ cell tumors derived from germ cell neoplasia in situ, germ cell tumors unrelated to germ cell neoplasia in situ, sex cord-stromal tumors, tumors containing both germ ...
Tonći Vodopić   +5 more
doaj   +1 more source

Temperature sensitivity of DNA double-strand break repair underpins heat-induced meiotic failure in mouse spermatogenesis

open access: yesCommunications Biology, 2022
High temperatures lead to DNA double-strand break accumulation and asynapsis that trigger the meiotic checkpoint and apoptosis of spermatocytes in ex vivo cultures, providing a rationale for the heat sensitivity of sperm production in mammals.
Kodai Hirano   +7 more
doaj   +1 more source

Rat PRDM9 shapes recombination landscapes, duration of meiosis, gametogenesis, and age of fertility

open access: yesBMC Biology, 2021
Background Vertebrate meiotic recombination events are concentrated in regions (hotspots) that display open chromatin marks, such as trimethylation of lysines 4 and 36 of histone 3 (H3K4me3 and H3K36me3).
Ondrej Mihola   +17 more
doaj   +1 more source

Synchronous Primary Parosteal Osteosarcoma and Primary Mediastinal Germ Cell Tumour with Atypical Mycobacterial Infection – A Rare Phenomenon: A Case Report [PDF]

open access: yesMalaysian Orthopaedic Journal, 2023
Mediastinal germ cell tumours are a rare group of extragonadal germ cell tumours with less than 5% prevalence of all germ cell tumours. Primary mediastinal germ cell tumours themselves account for 16-36% of the extragonadal germ cell tumours. Along the
Lim CH   +4 more
doaj   +1 more source

Treatment of Germ Cell Testicular Cancer

open access: yesActa Clinica Croatica, 2020
Germ-cell testicular cancer (GCTC) is a malignant neoplasm derived from the primordial germ cell. Although it accounts for approximately 1% of all malignancies in men, it is the most common cancer of younger male population, with the highest incidence ...
Ana Koši Kunac   +3 more
doaj   +1 more source

Surgical treatment of metastatic germ cell cancer

open access: yesAsian Journal of Urology, 2021
Among young men between the ages of 15 and 40 years, germ cell cancer is the most common solid tumor [1]. The worldwide incidence of germ cell cancer is 70 000 cases.
Andreas Hiester, Peter Albers
doaj   +1 more source

Germ cell markers in fishes - A review

open access: yesAquaculture and Fisheries, 2022
Identification of germ cell markers in fishes is crucial to track the germ cell differentiation and migration for manipulation of the cells to study sexual differentiation as well as to carry out transgenic transplantation techniques.
Sultana Begum   +3 more
doaj   +1 more source

Strategies for Mammalian Mesenchymal Stem Cells Differentiation into Primordial Germ Cell-Like Cells: A Review [PDF]

open access: yesCell Journal, 2022
Primordial germ cells develop into oocytes and sperm cells. These cells are useful resources in reproductive biology and regenerative medicine. The mesenchymal stem cells (MSCs) have been examined for in vitro production of primordial germ cell-like ...
Shabnam Fayezi   +3 more
doaj   +1 more source

Zebrafish as a Model for Germ Cell Regeneration

open access: yesFrontiers in Cell and Developmental Biology, 2021
Germ cell acts as a link between transfer of genetic information and process of species evolution. Defects or malformations of germ cells can lead to infertility or tumors.
Zigang Cao, Qifen Yang, Lingfei Luo
doaj   +1 more source

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