Results 171 to 180 of about 13,787 (250)

Predictors of First-Line Progression-Free Survival in Testicular Germ Cell Tumors: A Retrospective Cohort Study. [PDF]

Cancers (Basel)
Parosanu A, Nitipir C, Iaciu C, Stanciu M, Sinescu I, Baston C.   +5 more
europepmc   +1 more source

BRD9 inhibition as potential treatment option for testicular germ cell tumors

Andrology, EarlyView.
Abstract Background Testicular germ cell tumors (TGCT) are the predominant tumor in younger males. Usually, 5‐year survival rates are quite high, but 15–20% of patients with metastatic non‐seminomas are resistant to standard cisplatin‐based therapy.
Aylin Hansen, Christine Sanders, Florian Fronhoffs, Kai Funke, Glen Kristiansen, Hubert Schorle   +5 more
wiley   +1 more source

Novel PET tracers to distinguish the nature of residual masses after the completion of chemotherapy in metastatic testicular germ cell tumours: A systematic review. [PDF]

Eur J Nucl Med Mol Imaging
Bertocchi A, De Vincenzo F, Perrino M, Cordua N, Guglielmo P, Aliprandi M, Cecchi LG, Federico A, Panzardi A, Santoro A, Evangelista L, Zucali PA.   +11 more
europepmc   +1 more source

Semen quality in patients with testicular cancer is associated with age and with greatly elevated levels of beta human chorionic gonadotropin

Andrology, EarlyView.
Abstract Background Poor semen quality is a well‐known feature in patients with testicular germ cell tumours (GCTs) at the time of diagnosis but the underlying biological reasons are incompletely understood. Objectives This study aimed to identify GCT‐specific clinical factors that are involved with poor semen quality in GCT patients.
Klaus‐Peter Dieckmann, Johanna Hochmuth‐Tisch, Andrea Salzbrunn, Cord Matthies, Kathrein von Kopylow, Marta Godlewska, Christian Wülfing, Uwe Pichlmeier, Armin Soave, Christian Guido Ruf   +9 more
wiley   +1 more source

Pediatric malignant testicular germ cell tumors: a developmental and comparative perspective. [PDF]

Diagn Pathol
Chen S, Matoso A.
europepmc   +1 more source

Sperm Telomere Interactions Are Impaired in Testicular Cancer Before and After Adjuvant Therapy

Andrology, EarlyView.
ABSTRACT Background No study has yet explored telomere length or interaction in sperm nuclei of testicular cancer (TC) patients exposed to chemotherapy or radiotherapy. However, sperm telomere dynamics have emerged as a potential marker in male infertility.
Benoit Berby, Sylvianne Hennebicq, Jacqueline Saias, Florence Brugnon, Isabelle Berthaut, Myriam Daudin, Louis Bujan, Ludovic Dumont, Christine Rondanino, Aurélie Feraille, Nathalie Rives   +10 more
wiley   +1 more source

Primary ovarian synovial sarcoma in an adolescent mimicking a germ cell tumor: A case report and diagnostic challenge. [PDF]

Gynecol Oncol Rep
Listyaningtyas D, Nugroho H, Brahmantara BN, Heriyawati, Nandiaty AF.   +4 more
europepmc   +1 more source

Inhibition of HMGA2 Leads to Reduced Cell Proliferation and Increased Apoptosis in Human Embryonal Carcinoma Cell Lines

Andrology, EarlyView.
ABSTRACT Background The most prevalent solid tumors in young men are testicular germ cell tumors (TGCTs), and embryonal carcinoma is the most common subtype among non‐seminomatous germ cell tumors (NSGCTs). Despite the excellent cure rates of cisplatin‐based chemotherapy, resistance develops in 15%–30% of patients with metastatic cancer, which results ...
Marco De Martino, Matteo Lampitto, Alfredo Fusco, Marco Barchi, Francesco Esposito, Paolo Chieffi   +5 more
wiley   +1 more source

Spermatocytic Tumor Arising in a Cryptorchid Testis: A Case Report and Narrative Review. [PDF]

J Clin Med
Barbu LA, Mogoantă SS, Cercelaru L, Marinaș MC, Mărgăritescu ND, Popescu M, Căluianu V, Mogoș GFR, Vasile L, Țenea Cojan TS.   +9 more
europepmc   +1 more source

A Unified Machine Learning Model for Relapse Prediction in Clinical Stage I Testicular Cancer

Andrology, EarlyView.
ABSTRACT Background Approximately one‐fourth of patients with clinical stage I testicular cancer relapse. For decades, risk stratification has been based on different tumor characteristics for seminomas and non‐seminomas. Previous studies primarily used Cox proportional‐hazards models and included only a limited number of variables.
Thomas Wagner, Ramtin Zargari Marandi, Jakob Lauritsen, Daniel Dawson Murray, Mikkel Bandak, Birgitte Grønkær Toft, Dan Berney, Gedske Daugaard   +7 more
wiley   +1 more source