Results 181 to 190 of about 21,086 (311)

Analysis of Gene Expression in Aedes aegypti Suggests Changes in Early Genetic Control of Mosquito Development

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
ABSTRACT Aedes aegypti, a critical vector for tropical diseases, poses significant challenges for studying its embryogenesis due to difficulties in removing its rigid chorion and achieving effective fixation for in situ hybridization. Here, we present novel methodologies for fixation, dechorionation, DAPI staining, and in situ hybridization, enabling ...
Renata Coutinho‐dos‐Santos   +8 more
wiley   +1 more source

Second edition ICCR dataset for testicular germ cell tumours: a reporting guide for histopathological diagnosis of orchiectomy specimens. [PDF]

open access: yesHistopathology
Bremmer F   +12 more
europepmc   +1 more source

ParaHox Genes Revisited: From Gut Patterning to Integrated Axial and Neural Organization in Rotifera

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In rotifers, ParaHox genes show a dispersed genomic organization, with Xlox absent across gnathiferans. Exclusive neuronal expression of Gsx and Cdx reveals that ancestral ParaHox genes coordinated neural and epithelial development beyond gut patterning, suggesting an integrated role in early bilaterian body plan organization.
Andreas C. Fröbius   +2 more
wiley   +1 more source

The Expanding Role of Gene Sequencing in Shaping Fetal Therapies: Clinical and Ethical Considerations

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT In utero interventions are transformative in addressing genetic and anatomic conditions during fetal development. Next generation sequencing enables early genetic testing, playing a pivotal role in prenatal decision‐making by supporting risk stratification, precise and timely diagnosis, which directly informs eligibility for fetal surgical and
Matthew A. Shear   +7 more
wiley   +1 more source

GatorST: A Versatile Contrastive Meta‐Learning Framework for Spatial Transcriptomic Data Analysis

open access: yesSmall Methods, EarlyView.
GatorST learns spatially informed embeddings for spatial transcriptomics by coupling two‐hop subgraph graph convolutions with cluster‐aware pseudo‐label supervision and episodic contrastive meta‐learning. The framework captures neighbor‐level topology and tissue‐wide expression semantics without heavy augmentations, delivering robust representations ...
Zhenhao Zhang   +5 more
wiley   +1 more source

Thromboembolic disease in testicular germ cell tumors-real-world evidence of three Portuguese institutions. [PDF]

open access: yesFront Oncol
Albuquerque J   +11 more
europepmc   +1 more source

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