Results 221 to 230 of about 21,086 (311)

Inhibition of HMGA2 Leads to Reduced Cell Proliferation and Increased Apoptosis in Human Embryonal Carcinoma Cell Lines

Andrology, EarlyView.
ABSTRACT Background The most prevalent solid tumors in young men are testicular germ cell tumors (TGCTs), and embryonal carcinoma is the most common subtype among non‐seminomatous germ cell tumors (NSGCTs). Despite the excellent cure rates of cisplatin‐based chemotherapy, resistance develops in 15%–30% of patients with metastatic cancer, which results ...
Marco De Martino, Matteo Lampitto, Alfredo Fusco, Marco Barchi, Francesco Esposito, Paolo Chieffi   +5 more
wiley   +1 more source

Sperm Sexing in Selected Animals and Humans: Methods, Applications, and Future Prospects

Andrology, EarlyView.
ABSTRACT Background Sperm sexing is a technique that enables the selection of offspring sex by sorting spermatozoa based on their sex chromosomes. This technology has gained increasing attention due to its potential applications in both animal breeding and human‐assisted reproduction.
Domrazek Kinga, Jurka Piotr
wiley   +1 more source

[¹⁸F]F-FAPI-74 PET/CT for gonadal and extragonadal germ cell Tumors: a pilot study. [PDF]

EJNMMI Res
Kidess M, Siegmund SC, Unterrainer LM, Kazmierczak P, Hentrich M, Eismann L, Volz Y, Ebner B, Hermans J, Pyrgidis N, Apfelbeck M, Sheikh GT, Werner RA, Klauschen F, Stief CG, Ledderose ST, Chaloupka M.   +16 more
europepmc   +1 more source

Semen Cryopreservation in Testicular Cancer: Before or After Orchidectomy?

Andrology, EarlyView.
ABSTRACT Background Fertility preservation in patients with testicular cancer remains a clinical priority, yet the optimal timing for sperm cryopreservation—before or after orchidectomy—remains a matter of debate. Objectives The aim of this study was to determine the optimal timing for semen cryopreservation and the best‐quality sample for ART.
Alessandra Buonacquisto, Carlotta Pozza, Gaia Cicolani, Anna Chiara Conflitti, Luisa Caponecchia, Serena Bianchini, Enrico Delli Paoli, Marta Tenuta, Daniele Gianfrilli, Andrea M. Isidori, Francesco Lombardo, Francesco Pallotti, Donatella Paoli   +12 more
wiley   +1 more source

Liposarcoma Arising From Mature Teratoma Following Testicular Tumor Surgery: A Case Report. [PDF]

IJU Case Rep
Yamazaki M, Kitamura K, Ogura K, Oomae G, Mizushima K, Nonami T, Miyoshi Y, Sakamoto Y, Muto S.   +8 more
europepmc   +1 more source

A Unified Machine Learning Model for Relapse Prediction in Clinical Stage I Testicular Cancer

Andrology, EarlyView.
ABSTRACT Background Approximately one‐fourth of patients with clinical stage I testicular cancer relapse. For decades, risk stratification has been based on different tumor characteristics for seminomas and non‐seminomas. Previous studies primarily used Cox proportional‐hazards models and included only a limited number of variables.
Thomas Wagner, Ramtin Zargari Marandi, Jakob Lauritsen, Daniel Dawson Murray, Mikkel Bandak, Birgitte Grønkær Toft, Dan Berney, Gedske Daugaard   +7 more
wiley   +1 more source

Metastatic Patterns of Malignant Germ Cell Tumors Vary by Histologic Subtype and Primary Site. [PDF]

Medicina (Kaunas)
Park HK.
europepmc   +1 more source

Testicular SIRT1 Loss Reveals an Aging‐Like Proteomic Landscape and Precipitates Reproductive Deterioration

Andrology, EarlyView.
ABSTRACT Background Advanced paternal age is associated with reduced male fertility and testicular dysfunction. Among the molecular regulators involved in aging, SIRT1, a NAD+‐dependent deacetylase, plays a pivotal role in maintaining oxidative balance and cellular homeostasis.
María Iniesta‐Cuerda, Jiřina Havránková, Hedvika Řimnáčová, Jiří Moravec, František Liška, Martin Knytl, Milena Králíčková, Jan Nevoral   +7 more
wiley   +1 more source

Chest CT in Testicular Mass Evaluation: A Stepwise Approach to Minimize Radiation Exposure.

Urol Int
Eigner E, Malshy K, Fazaa N, Nsair A, Atallah M, Amiel GE, Hoffman A.   +6 more
europepmc   +1 more source

Expression and therapeutic potential of TROP2 in cisplatin-resistant germ cell tumors. [PDF]

J Cancer Res Clin Oncol
Sperber L, von Brandenstein M, Kessler C, Heidenreich J, Storz E, Pfister D, Paffenholz P, Tolkach Y, Bernhardt M, Wirtz R, Eckstein M, Heidenreich A, Weiten R.   +12 more
europepmc   +1 more source