ABSTRACT Background Testicular germ cell tumours (TGCT) are the most common malignancies among young men and represent a major threat to reproductive health. Both the disease itself and oncological treatments, particularly chemotherapy, can compromise spermatogenesis and semen quality.
Ondrej Sanovec +18 more
wiley +1 more source
Evaluation of the relationship between pan-immune inflammation value and prognostic factors in germ-cell testicular cancer: analysis of stage, lymph node involvement, and metastasis. [PDF]
Dinçer E +5 more
europepmc +1 more source
Evolution and the Embryo: The Evidence for Special Creation [PDF]
Mauceri, Joseph M.
core +1 more source
ABSTRACT Background Testicular germ cell tumours (TGCTs) are the most common type of tumour diagnosed in young men, and reliable non‐invasive biomarkers are crucial for clinical management. MicroRNAs (miRNAs) from the miR‐371–373 cluster have recently been identified as novel and more sensitive serum biomarkers than the conventional protein‐based ...
Nina Mørup +7 more
wiley +1 more source
Early Recurrence of Mediastinal Germ Cell Tumor With Pathological Complete Response to Chemotherapy: A Case Report. [PDF]
Kanai R, Yokoyama S, Fukao D, Sakabe M.
europepmc +1 more source
Incidence of Gonadal and Extragonadal Germ Cell Tumours in Patients With Klinefelter Syndrome
ABSTRACT Background Klinefelter's syndrome (KS; 47, XXY) is associated with an altered risk profile for malignancies compared with non‐KS males. In particular, several reports have noted a striking association between KS and extragonadal germ cell tumours (EGCTs), especially in the mediastinum, whereas the risk of testicular germ cell tumours (TGCTs ...
Aksh Tailor +6 more
wiley +1 more source
A Case of Complete Remission Achieved Through Stereotactic Radiotherapy for Isolated Bone Metastasis Following Four Courses of Bleomycin, Etoposide, and Cisplatin Chemotherapy for Testicular Cancer. [PDF]
Arinami K +7 more
europepmc +1 more source
ABSTRACT Background Familial clustering of testicular germ cell tumour (TGCT) is well‐established, whereas the risk of non‐testicular cancer among relatives remains inconsistent across studies. Objective To evaluate the overall and site‐specific cancer risk among first‐degree relatives and grandparents of TGCT patients compared to cancer‐free controls.
Csilla Krausz +13 more
wiley +1 more source
Retrospective Evaluation of Childhood Germ Cell Tumors: A Single-Center Experience. [PDF]
Selamioglu A +7 more
europepmc +1 more source
ABSTRACT Background The tight junction protein CLDN6 has been identified as a cancer‐associated cell surface marker that is rarely expressed in healthy tissues. In testicular germ cell tumors (GCT), CLDN6 is particularly detectable in seminomas, embryonal carcinomas, and choriocarcinomas.
Jule Zwick +7 more
wiley +1 more source

