Results 171 to 180 of about 8,866 (208)

Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer

Advanced Science, EarlyView.
Breast cancer cells undergo metabolic and transcriptomic reprogramming to support aberrant cell proliferation. Their mitochondria rely on the transfer of phosphatidylcholine from the endoplasmic reticulum to their membranes by STARD7, a candidate upregulated in breast cancer, to be functional.
Ewelina Dondajewska, Paula Allepuz‐Fuster, Chloé Maurizy, Alexandre Hego, Sandra Ormenese, Quentin Lion, Arnaud Blomme, Pierre Close, Arnaud Lavergne, Latifa Karim, Marc Thiry, Ivan Nemazanyy, Roopesh Krishnankutty, Jair Marques Jr, Alex von Kriegsheim, Nathaniel F. Henneman, Ganna Panasyuk, Kateryna Shostak, Alain Chariot   +18 more
wiley   +1 more source

Comprehensive evaluation of phosphoproteomic-based kinase activity inference. [PDF]

Nat Commun
Müller-Dott S, Jaehnig EJ, Munchic KP, Jiang W, Yaron-Barir TM, Savage SR, Garrido-Rodriguez M, Johnson JL, Lussana A, Petsalaki E, Lei JT, Dugourd A, Krug K, Cantley LC, Mani DR, Zhang B, Saez-Rodriguez J.   +16 more
europepmc   +1 more source

Characterization of B Cell Responses in Rainbow Trout (Oncorhynchus Mykiss) Affected by Red Mark Syndrome

Advanced Science, EarlyView.
This study extensively characterizes the B cell response of rainbow trout (Oncorhynchus mykiss) in response to red mark syndrome (RMS). This disease, suspected to be caused by a Midichloria‐like organism (MLO), induces skin lesions in the infected animals, characterized by a massive influx of IgM+ B cells.
J Germán Herranz‐Jusdado, Samuel Vicente‐Gil, Esther Morel, Pablo Jiménez‐Barrios, Rocío Simón, Pedro Perdiguero, Diana Martín, Marta Vargas‐Ramírez, Niels Lorenzen, Jacob Günther Schmidt, Carolina Tafalla   +10 more
wiley   +1 more source

Perivascular space and white matter hyperintensities in Alzheimer's disease: associations with disease progression and cognitive function. [PDF]

Alzheimers Res Ther
Schirge PM, Perneczky R, Taoka T, Ruiz-Rizzo AL, Ersoezlue E, Forbrig R, Guersel S, Kurz C, Brendel M, Hellmann-Regen J, Priller J, Schneider A, Jessen F, Düzel E, Buerger K, Teipel S, Laske C, Peters O, Spruth E, Fliessbach K, Rostamzadeh A, Glanz W, Janowitz D, Kilimann I, Sodenkamp S, Ewers M, Rauchmann BS.   +26 more
europepmc   +1 more source

Development and Breeding of Herbicide‐Resistant Sorghum for Effective Cereal‐Legume Intercropping

Advanced Science, EarlyView.
This study identified two SbALS mutations (A93T and S624N) conferring robust herbicide resistance in sorghum, facilitating efficient weed control. Structural analysis revealed that imazamox resistance is mediated by disrupted herbicide binding. Furthermore, 126 imazamox resistant soybean varieties are screened for sorghum‐soybean intercropping ...
Sanyuan Tang, Jiayang Shi, Xuefeng Li, Mingliang Yang, Chao Li, Dan Zhang, Sen Yang, Cuo Mei, Zuyong Luo, Li Zhang, Wanke Zhang, Chunrui Zhang, Chenbo Zhu, Xiaowei Ma, Ran Xia, Yuhang Chen, Jinsong Zhang, Qingshan Chen, Shouyi Chen, Qi Xie, Feifei Yu   +20 more
wiley   +1 more source

Multi-Layered Molecular Profiling Informs the Diagnosis and Targeted Therapy of Desmoplastic Small Round Cell Tumor

Fröhling S, Renner M, Oleś M, Paramasivam N, Heilig C, Schneider A, Modugno C, Herremans C, Hüllein J, Hutter B, Erkut C, Mock A, Krieghoff-Henning E, Jensen C, Sakhteman A, The M, Prinz T, Lajer P, Baude-Müller A, Beck K, Beuthien-Baumann B, Apostolidis L, Bauer S, Boerries M, Brandts C, Rieke D, Kindler T, Klauschen F, Schulze-Osthoff K, Schlenk R, Berchem G, Allgäuer M, Mechtersheimer G, Stenzinger A, Lipka D, Schlesner M, Küster B, Jahn A, Schröck E, Heining C, Teleanu M, Horak P, Kreutzfeldt S, Hübschmann D, Hartmann W, Glimm H.   +45 more
europepmc   +1 more source

Emergence of transferable daptomycin resistance in Gram-positive bacteria. [PDF]

NPJ Antimicrob Resist
Marciniak T, Kirchner L, Wolf SA, Walther B, Bischler T, Nyasinga J, Gunturu R, Semmler T, Gräfenhan T, Whitelaw A, Scherf-Clavel O, Holzgrabe U, Ziebuhr W.   +12 more
europepmc   +1 more source

The role of plasma-derived small extracellular vesicles in pre-metastatic niche formation through modulation of macrophages in head and neck squamous cell carcinoma. [PDF]

Br J Cancer
Huber D, Kors TA, Schütt L, Hofmann L, Betzler A, Lotfi R, Oliveri F, Schmid S, Wollenberg B, Hoffmann TK, Brunner C, Theodoraki MN.   +11 more
europepmc   +1 more source

Shared decision-making improves adherence to mesalamine in ulcerative colitis: A prospective, multicenter, non-interventional cohort study in Germany. [PDF]

World J Gastroenterol
Kruis W, Jessen P, Morgenstern J, Reimers B, Müller-Grage N, Bokemeyer B.   +5 more
europepmc   +1 more source

Ki-67 as a Prognostic Marker in Squamous Cell Carcinomas of the Vulva: A Systematic Review. [PDF]

J Clin Med
Klamminger GG, Eltze E, Bitterlich A, Degirmenci Y, Hasenburg A, Wagner M, Nigdelis MP.   +6 more
europepmc   +1 more source