Results 101 to 110 of about 26,681 (151)

The Role of TNF Receptor-Associated Factor 5 in the Formation of Germinal Centers by B Cells During the Primary Phase of the Immune Response in Mice. [PDF]

Int J Mol Sci
Hikosaka-Kuniishi M, Iwata C, Ozawa Y, Ogawara S, Wakaizumi T, Itaya R, Sunakawa R, Sato A, Nagai H, Morita M, So T.   +10 more
europepmc   +1 more source

Interleukin-4 downregulates transcription factor BCL6 to promote memory B cell selection in germinal centers. [PDF]

Immunity
Shehata L, Thouvenel CD, Hondowicz BD, Pew LA, Pritchard GH, Rawlings DJ, Choi J, Pepper M.   +7 more
europepmc   +1 more source

Autoimmunity to stromal-derived autoantigens in rheumatoid ectopic germinal centers exacerbates arthritis and affects clinical response. [PDF]

J Clin Invest
Corsiero E, Caliste M, Jagemann L, Fossati-Jimack L, Goldmann K, Cubuk C, Ghirardi GM, Prediletto E, Rivellese F, Alessandri C, Hopkinson M, Javaheri B, Pitsillides AA, Lewis MJ, Pitzalis C, Bombardieri M.   +15 more
europepmc   +1 more source

Anti-PD-1 chimeric antigen receptor T cells efficiently target SIV-infected CD4+ T cells in germinal centers. [PDF]

J Clin Invest
Eichholz K, Fukazawa Y, Peterson CW, Haeseleer F, Medina M, Hoffmeister S, Duell DM, Varco-Merth BD, Dross S, Park H, Labriola CS, Axthelm MK, Murnane RD, Smedley JV, Jin L, Gong J, Rust BJ, Fuller DH, Kiem HP, Picker LJ, Okoye AA, Corey L.   +21 more
europepmc   +1 more source

Targeted checkpoint control of B cells undergoing positive selection in germinal centers by follicular regulatory T cells. [PDF]

Proc Natl Acad Sci U S A
Ke F, Benet ZL, Shelyakin P, Britanova OV, Gupta N, Dent AL, Moore BB, Grigorova IL.   +7 more
europepmc   +1 more source

1201 SGLT2 inhibitors modulate inflammation and germinal centers in lupus

Lupus Science and Medicine
Javier Rangel-Moreno, Mary O’Connell, Jennifer H Anolik, Maria de la Luz Garcia-Hernandez, Daria Krenitsky, Maria Fernanda Ossa-Echeverri, Mark Lusco, John Looney   +7 more
doaj   +1 more source

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Germinal Centers

Annual Review of Immunology, 1994
Germinal centers develop in the B cell follicles of secondary lymphoid tissues during T cell-dependent (TD) antibody responses. The B cells that give rise to germinal centers initially have to be activated outside follicles, in the T cell-rich zones in association with interdigitating cells and T cell help.
Ian C M Maclennan, I C Maclennan
exaly   +3 more sources

Invasion of the germinal centers

Cell, 2023
After vaccination or infection, long-lived germinal centers can produce antibodies with high affinity and specificity against pathogens. In this issue of Cell, de Carvalho et al. and Hägglöf et al. show that naive B cells can invade germinal centers, replacing B cells that entered early and changing features of antibody production.
Daniel P, Maurer, Aaron G, Schmidt
openaire   +2 more sources

Selection in the germinal center

Current Opinion in Immunology, 2020
Germinal centers (GCs) are well known for their important role in shaping the secondary B cell repertoire to generate antibodies capable of binding with high-affinity and specificity to foreign antigens. Somatic hypermutation of the Ig variable region genes in GC B cells represents a highly efficient mechanism for generating new antibody variants with ...
Angelica Wy, Lau, Robert, Brink
openaire   +2 more sources