Results 131 to 140 of about 289,899 (373)

Cancer Stem Cells Shift Metabolite Acetyl‐Coenzyme A to Abrogate the Differentiation of CD103+ T Cells

open access: yesAdvanced Science, EarlyView.
Lei et al. demonstrate that cancer stem cells (CSCs) play a pivotal role in impairing the differentiation of CD103+ T cells in patients with non‐small‐cell lung cancer. The key mechanism involves CSC‐derived acetyl‐CoA, which disrupts CD103+ T cell differentiation by sequentially inducing acetylation and ubiquitination of the Blimp‐1 protein. Targeting
Jiaxin Lei   +10 more
wiley   +1 more source

Nurses experience on modern technologies and patient safety within Gerontology Care in Finland : Literature Review [PDF]

open access: yes, 2016
Gerontology is a growing field of nursing especially with the rapid increase of aging population in most of the developed countries. This has made modern technology in gerontology also known as gerotechnology essential in taking care of elderly patients.
Järvinen, Judith   +2 more
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Pre‐Existing Th1 Immunity Outperforms Age in Predicting Antibody Responses to SARS‐CoV‐2 Inactivated Vaccines

open access: yesAdvanced Science, EarlyView.
Challenging the focus on age, this study finds pre‐existing T helper 1 cells are the key biomarker for predicting antibody response to SARS‐CoV‐2 inactivated vaccines. In both mice and humans, high responders exhibited elevated baseline T helper 1 cells, which correlated with robust humoral immunity, offering crucial guidance for improving vaccine ...
Chanyuan Ye   +12 more
wiley   +1 more source

Why Engagement Matters to Gerontological Student Learning [PDF]

open access: gold, 2020
Christine A. Fruhauf   +4 more
openalex   +1 more source

Single‐Cell Profiling Across Immune Tissues and Organs Reveals Immunosenescence Signatures in Male Rhesus Monkeys

open access: yesAdvanced Science, EarlyView.
Single‐cell profiling across bone marrow, spleen, mesenteric lymph, and blood in rhesus monkeys reveals organ Immunosenescence. GZMB rises with age, particularly in cytotoxic and terminally exhausted CD8+ T cells, and BHLHE40 emerges as a key transcription factor enriched across multiple CD8+ subsets, regulating pro‐inflammatory and exhaustion‐related ...
Shengnan Wang   +10 more
wiley   +1 more source

Prevention of COVID-19 in Older Adults: A Brief Guidance from the International Association for Gerontology and Geriatrics (IAGG) Asia/Oceania Region

open access: yesThe Journal of Nutrition, Health & Aging, 2020
J. K. Chhetri   +7 more
semanticscholar   +1 more source

Iowa Health Focus, September 2004 [PDF]

open access: yes, 2004
Monthly newsletter for the Iowa Department of Public ...

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