Results 131 to 140 of about 246,242 (358)

“Listen Carefully:” A Study of Ageist Stereotypes and Undergraduates’ Desire to Work with Elders [PDF]

open access: yes, 2013
“Listen Carefully:” A Study of Ageist Stereotypes and Undergraduates’ Desire to Work with Elders identifies and assesses how prior experience with elders and ageist stereotypes informs the degree to which undergraduates are inclined (or disinclined) to ...
Ilg, Genevieve
core   +1 more source

SenExo‐cCCT2 Reprograms Senescence Response and Anti‐Tumor Immunity Following FOLFIRINOX Chemotherapy in Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
This study demonstrates that SenExo‐cCCT2 enables targeted delivery of cCCT2 to pancreatic cancer cells, where it disrupts IPO13‐mediated nuclear translocation of UBC9, impairing SUMOylation‐dependent DNA damage repair and inducing senescence. Senescent tumor cells secrete CXCL10 to recruit CD8⁺ T‐cells while upregulating PD‐L1.
Shuncang Zhu   +18 more
wiley   +1 more source

Structural Basis of GABAB Receptor Activation during Evolution

open access: yesAdvanced Science, EarlyView.
This study explores the structural and functional mechanisms of the drosophila GABAB receptor, a key role in neurotransmission. Using cryo‐EM, the research reveals how the receptor's activation differs from its human counterpart, highlighting unique evolutionary features.
Guofei Hou   +14 more
wiley   +1 more source

The embodied and relational nature of the mind: implications for clinical interventions in aging individuals and populations

open access: yesClinical Interventions in Aging, 2013
W Jack Rejeski,1 Lise Gauvin2 1Department of Health and Exercise Science and Department of Geriatric Medicine, Wake Forest University, Winston-Salem, NC, USA; 2Research Center of the University of Montréal Hospital Center, Department of Social and
Rejeski WJ, Gauvin L
doaj  

Home accidents amongst elderly people: A locality study in Scotland [PDF]

open access: yes, 2007
Aim The aim of this locality study was to collect information on reported and unreported accidents amongst elderly people living in one locality in Scotland.
Banks, P   +6 more
core  

Is Gerontology Interdisciplinary? [PDF]

open access: yesThe Journals of Gerontology Series B: Psychological Sciences and Social Sciences, 2007
openaire   +3 more sources

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang   +15 more
wiley   +1 more source

Home - About - Disclaimer - Privacy