Results 71 to 80 of about 258,716 (360)
Bodily disintegration and successful ageing in Body Bereft by Antjie Krog
Antjie Krog’s Body Bereft (2006) details both the bodily changes brought about by older age and the ways in which these changes fracture a person’s previously-stable sense of self.
Antoinette Pretorius
doaj +1 more source
Artesunate Inhibits Neointimal Hyperplasia by Promoting IRF4 Associated Macrophage Polarization
This study shows that macrophage interferon regulatory factor 4 (IRF4) improved arterial injury‐induced neointimal hyperplasia by promoting of M2 polarization via up‐regulating krüppel‐like factor 4 (KLF4) in rodent and nonhuman primate models. Notably, artesunate is identified as a potent inducer of IRF4 in macrophages, and proposed as a promising ...
Jinlin Miao+15 more
wiley +1 more source
Connecting Bayes factor and the Region of Practical Equivalence (ROPE) Procedure for testing interval null hypothesis [PDF]
There has been strong recent interest in testing interval null hypothesis for improved scientific inference. For example, Lakens et al (2018) and Lakens and Harms (2017) use this approach to study if there is a pre-specified meaningful treatment effect in gerontology and clinical trials, which is different from the more traditional point null ...
arxiv
Critical educational gerontology : a third statement of first principles [PDF]
This article elaborates upon the initial statement of first principles for critical educational gerontology [CEG] established by Glendenning and Battersby some two decades ago, whilst taking stock of the body of critique levelled at such principles by ...
Formosa, Marvin
core
The N‐acetyltransferase‐10 (NAT10)‐mediated mRNA N4‐acetylcytidine modification enhances the stability of CXCL2 and KLF5 mRNA. Then, secreted CXCL2 promotes M2 macrophage polarization and oncostatin M secretion, activating NAT10 expression via STAT3 signaling.
Chen Chen+17 more
wiley +1 more source
Health debilitation negatively impacts the physical and psychiatric states of ageing persons, consequently increasing individual, familial, and social burdens.
Fung Kei Cheng
doaj +1 more source
As a plant‐derived flavonoid, apigenin directly targets PRDX6 to inhibit its PLA2 activity, blocking HSPA8 activation and disturbing its interactions with ATM and p38MAPK in senescent cells. By dampening wide spectrum expression of the SASP, apigenin prevents loss of tissue homeostasis, improves organ function, and alleviates multiple age‐related ...
Hongwei Zhang+10 more
wiley +1 more source
A Quantitative Method for Estimating the Human Development Stages by Based on the Health State Function Theory and the Resulting Deterioration Process [PDF]
The Health State Function theory is applied to find a quantitative estimate of the Human Development Stages by defining and calculating the specific age groups and subgroups. Early and late adolescence stages, first, second and third stages of adult development are estimated along with the early, middle and old age groups and subgroups.
arxiv
Female gerontology in TV-advertising [PDF]
The paper backgrounds the necessity of theoretical advancing the female gerontology project. Two models of female gerontology problems interpretation are considered: the model of “mail dominance” and the model of “female narcissism”.
doaj
UNO Website: Gerontology - Gerontology Advisory Board [PDF]
UNO Website: Department of Gerontology - Advisory ...
University of Nebraska at Omaha, UNO Department of Gerontology
core +1 more source