Results 101 to 110 of about 7,331 (186)

The Prediction of Pre‐Eclampsia Using Low Fetal Fraction in a Machine Learning Model

Prenatal Diagnosis, Volume 46, Issue 2, Page 236-242, February 2026.
ABSTRACT Objective To investigate the association between low fetal fraction (FF) in non‐invasive prenatal testing (NIPT) and pregnancy complications or adverse pregnancy outcomes. Methods Sixty‐four pregnant women undergoing NIPT at the Second Affiliated Hospital of Wenzhou Medical University between 13 June 2019 and 6 January 2023 had an initial NIPT
Jinyuan Wang, Yuxiao Bai, Shengshan Huang, Yao Lin, Songdao Ye, Wangxiao Zhou, Shanshan Li, Ni Li, Minghua Jiang, Xiaoou Wang   +9 more
wiley   +1 more source

Free Fetal Haemoglobin in Severe Early‐Onset Fetal Growth Restriction: A Prospective Multi‐Centre Study

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 3, Page 401-411, February 2026.
ABSTRACT Objective To assess fetal circulating free fetal haemoglobin (fHbF) levels and heme defences, correlated to fetal circulatory biometry and fetal sex in severe early‐onset fetal growth restriction (FGR). Design, Setting and Population A prospective study severe early‐onset fetal growth restriction pregnancies with close clinical management ...
Adam Brook, Georgia Baynes, Jonathan Scargill, Angelos Evangelinos, Charlotte Brennan‐Richardson, Freya Dow, Yuval Ginsberg, Tal Weissbach, Jana Brodszki, Eva Hansson, Anke Diemert, Kurt Hecher, Katarzyna Maksym, Neil Marlow, Rebecca N. Spencer, Anna L. David, Stefan R. Hansson, Paul Brownbill   +17 more
wiley   +1 more source

Aspirin Discontinuation at 24–28 Weeks and Placental Biomarker Trajectories: Post Hoc Analysis of a Randomised Trial

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 3, Page 432-441, February 2026.
ABSTRACT Objective To compare the trajectories of placental biomarkers throughout pregnancy after aspirin discontinuation at 24–28 weeks with those of a cohort treated until 36 weeks of gestation. Design A longitudinal secondary analysis of the StopPRE trial, using repeated measures of soluble fms‐like tyrosine kinase‐1 (sFlt‐1), placental growth ...
Erika Bonacina, Mireia Armengol‐Alsina, Pablo Garcia‐Manau, Monica López, Alicia Rodriguez‐Zurita, Àngels Vives, Eva Lopez‐Quesada, Marta Ricart, Anna Maroto, Laura de Mingo, Elena Pintado, Andrea Arias‐Garcia, Lourdes Martín, Carolina Chulilla‐Pérez, Esperanza Garcia, Mar Pallarols, Laia Vidal‐Sagnier, Mireia Teixidor, Carmen Orizales‐Lago, Adela Pérez‐Gomez, Vanesa Ocaña, Linda Puerto, Pilar Millán, Sonia Diaz, Ester del Barco, Marta Dalmau, Valeria Rolle, Elena Carreras, Anna Suy, Manel Mendoza   +29 more
wiley   +1 more source

Gestational Trophoblastic Disease in Brazil [PDF]

Revista Brasileira de Ginecologia e Obstetrícia, 2019
Antonio Braga, Lawrence Hsu Lin, Izildinha Maestá, Sue Yazaki Sun, Elza Uberti, José Mauro Madi, Maurício Viggiano   +6 more
doaj   +1 more source

A Novel Human Cellular System for Studying Normal Aging and for Anti‐Aging Discovery

Aging Cell, Volume 25, Issue 2, February 2026.
This study introduces a human cellular aging model using placental trophoblasts (hTSC‐STBs) that mimics key aging features like senescence and genomic instability. It aligns with human tissue aging and responds to anti‐aging treatments, offering a scalable platform to screen potential therapies and bridge lab findings to clinical applications ...
Zhen Feng, Cheuk Shuen Li, Haifeng Fu, Wenxin Jiang, Weiyu Zhang, Yingzhang Huang, Yunying Huang, Timothy Theodore Ka Ki Tam, Yang Li, Fang Liu, Liming Lu, Yin Lau Lee, William Shu Biu Yeung, Gordon Dougan, Pentao Liu   +14 more
wiley   +1 more source

The Secretome of Human Trophoblast Stem Cells Attenuates Senescence‐Associated Traits

Aging Cell, Volume 25, Issue 2, February 2026.
Human trophoblast stem cell‐derived secretome/conditioned medium (hTSC‐CM) and the extracellular vesicles (EVs) therein suppress DNA damage and NF‐κB activation in senescent fibroblasts, in turn reducing the production of senescence‐associated secretory phenotype (SASP) factors. This study highlights hTSC‐CM and EVs as potential senotherapeutic agents.
Kotb Abdelmohsen, Jennifer L. Martindale, Martina Rossi, Chang Hoon Shin, Apala Pal, Rachel Munk, Martin Salamini‐Montemurri, Mirko Baranzini, Ethan M. Arends, Maja Mustapic, Yuta Lee, Jau‐Nan Lee, Sicco H. Popma, Justin Hu, Nathan Duda, Carlos J. Nogueras‐Ortiz, Dimitrios Kapogiannis, Chang‐Yi Cui, Myriam Gorospe   +18 more
wiley   +1 more source

Clinical Features of Gestational Trophoblastic Disease in Aged Women in South Vietnam. [PDF]

Yonsei Med J, 2023
Nguyen BQ, Vo TM, Phan VTT, Nguyen C, Vu H, Vo B.   +5 more
europepmc   +1 more source

Management of Molar‐Pregnancy and Associated Gestational Trophoblastic Neoplasia at a Specialised Unit: 10‐Year Review

Australian and New Zealand Journal of Obstetrics and Gynaecology, Volume 66, Issue 1, February 2026.
ABSTRACT Patients diagnosed with gestational trophoblastic diseases (GTD) can develop malignant gestational trophoblastic neoplasia (GTN). ß‐hCG monitoring is important in the early detection of GTN. The primary outcome of this study was to describe ß‐hCG monitoring completion rates and time from GTN diagnosis to chemotherapy commencement for patients ...
Harrison Odgers, Shannon Philp, Trevor Tejada‐Berges   +2 more
wiley   +1 more source

PD-L1 in gestational trophoblastic disease: an antibody evaluation. [PDF]

Acta Obstet Gynecol Scand, 2022
Hoeijmakers YM, Simons M, Bulten J, Gorris MAJ, Ottevanger PB, de Vries IJM, Sweep FCGJ.   +6 more
europepmc   +1 more source

Advanced Paternal Age Impacts Common Loci in the Sperm and Placenta DNA Methylomes

Andrology, Volume 14, Issue 2, Page 528-544, February 2026.
ABSTRACT Background Epidemiological studies have reported an association between advanced paternal age at conception and an increased risk of neurodevelopmental disorders in offspring, such as autism spectrum disorder. Evidence suggests that DNA methylation alterations in spermatozoa of older men may be transmitted to the feto‐placental unit and ...
Julia Barnwell, Sophia Rahimi, Sherri Lee Jones, Donovan Chan, Josée Martel, Sara Abdessamie, Catherine M. Herba, Jean R. Séguin, William D. Fraser, Celia M. T. Greenwood, Tuong‐Vi Nguyen, Tina C. Montreuil, Jacquetta Trasler   +12 more
wiley   +1 more source