Results 101 to 110 of about 14,312 (250)

MicroRNA-34a is a tumor suppressor in choriocarcinoma via regulation of Delta-like1 [PDF]

, 2013
Background: Choriocarcinoma is a gestational trophoblastic tumor which causes high mortality if left untreated. MicroRNAs (miRNAs) are small non protein-coding RNAs which inhibit target gene expression.
Chiu, PCN, Lam, KKW, Lee, CL, Leung, CON, Pang, RTK, Ye, TM, Yeung, WSB   +6 more
core   +2 more sources

An update on pacemaking in the myometrium

The Journal of Physiology, EarlyView.
Abstract figure legend The spread of multiple electrical signals (panel A, blue‐to‐red indicates increasing electrical excitability) that are spatiotemporally distinct, yet in‐phase with the excitatory episode, determines action potential shape and form (panel B, as recorded by single cell microelectrodes) and ensures contractile amplitude and duration
Susan Wray, Michael J. Taggart
wiley   +1 more source

Gestational Trophoblastic Disease-induced Thyroid Storm

Clinical Practice and Cases in Emergency Medicine, 2019
In the United States, gestational trophoblastic diseases (GTD), including molar pregnancies, occur in 121 out of 100,000 pregnancies. 1 Many patients with GTD may develop hyperthyroidism.
Carly Blick, Kraftin E. Schreyer
doaj   +1 more source

ESM‐1 and GBP‐1 are associated with endothelial dysfunction: emerging biomarkers or key players in the pathophysiology of preeclampsia?

The Journal of Physiology, EarlyView.
Abstract figure legend Endothelial specific molecule‐1 (ESM‐1) and guanylate binding protein‐1 (GBP‐1) are proteins that are produced by activated/dysfunctional endothelial cells and are increased and decreased, respectively, during preeclampsia. It remains to be established whether ESM‐1 and GBP‐1 could potentially be included as biomarkers for the ...
Ines Pronk, Joost H. N. Schuitemaker, Marijke M. Faas, Alexandra M. Smink   +3 more
wiley   +1 more source

Excessive hypercholesterolaemia during pregnancy as a risk factor for endothelial dysfunction in pre‐eclampsia

The Journal of Physiology, EarlyView.
Abstract figure legend Excessive hypercholesterolaemia during pregnancy impairs maternal endothelial function, which, in turn, drives the development of pre‐eclampsia and may also contribute to the increased risk of later‐life cardiovascular disease in women.
Amanda A. de Oliveira, Floor Spaans, Christy‐Lynn M. Cooke, Sandra T. Davidge   +3 more
wiley   +1 more source

Vaginal epithelioid trophoblastic tumor mimicking vaginal fistula: a case report and literature review

Frontiers in Oncology
BackgroundEpithelioid trophoblastic tumor (ETT) is a rare variant of gestational trophoblastic neoplasia. This article presents a case of vaginal ETT, initially misdiagnosed as vaginal carcinoma, in a patient with no history of gestational trophoblastic ...
Dong-mei Li, Dong-mei Li, Xiu-zhang Yu, Xiu-zhang Yu, Ming-rong Qie, Ming-rong Qie, Rui-qi Duan, Rui-qi Duan   +7 more
doaj   +1 more source

Placental mitochondrial metabolic adaptation maintains cellular energy balance in pregnancy complicated by gestational hypoxia

The Journal of Physiology, EarlyView.
Abstract figure legend Placental mitochondrial adaptation to gestational hypoxia. Hypoxic pregnancy in sheep increases placental insulin like growth factor 2 (IGF2) signalling (1), which is associated with a shift in capacity away from β‐oxidation (2) and complex I‐mediated respiration (3), while maintaining total oxidative phosphorylation capacity (4).
Wen Tong, Beth J. Allison, Kirsty L. Brain, Olga V. Patey, Youguo Niu, Kimberley J. Botting, Sage G. Ford, Tess A. Garrud, Peter F. B. Wooding, Qiang Lyu, Lin Zhang, Jin Ma, Alice P. Sowton, Katie A. O'Brien, Tereza Cindrova‐Davies, Hong Wa Yung, Graham J. Burton, Andrew J. Murray, Dino A. Giussani   +18 more
wiley   +1 more source

Unusual Site of Metastasis of Placental Site Trophoblastic Tumor: Case Report and Literature Review

Middle East Journal of Cancer, 2018
Placental site trophoblastic tumor is a subtype of gestational trophoblastic neoplasm with unpredictable clinical behavior. Cytoreductive surgery is the cornerstone of treatment.
Leila Mousavi Seresht, Hamed Golmohamadzadeh, Zohreh Yousefi, Amir Hosein Jafarian, Ali Moghimi, Mojgan Soltani   +5 more
doaj  

Assessment of risk factors associated with post-molar gestational trophoblastic neoplasia: a retrospective cohort [PDF]

Revista Brasileira de Ginecologia e Obstetrícia
Objective: Evaluate the risk factors for the development of post-molar gestational trophoblastic neoplasia. Methods: Retrospective cohort study with 320 women with gestational trophoblastic disease (GTD) followed in a tertiary hospital from January 2005
Silvia Regina Piazzetta, Karin Anspach Hoch, Cristina Laguna Benetti-Pinto, Daniela Angerame Yela   +3 more
doaj   +1 more source

Endothelial‐to‐mesenchymal transition in the fetoplacental macrovasculature and microvasculature in pregnancies complicated by gestational diabetes

The Journal of Physiology, EarlyView.
Abstract figure legend Transforming growth factor (TGF)‐β2 and interleukin (IL)‐1β induced morphological and molecular changes consistent with endothelial‐to‐mesenchymal transition (EndMT) in HUVECs isolated from both pregnancies complicated by gestational diabetes (GDM) and non‐GDM pregnancies.
Abigail R. Byford, Georgia Fakonti, Ziyu Shao, Sharanam Soni, Sophie L. Earle, Muath Bajarwan, Lara C. Morley, Beth Holder, Eleanor M. Scott, Karen Forbes   +9 more
wiley   +1 more source