Results 81 to 90 of about 14,312 (250)

Biological functions of hCG and hCG-related molecules [PDF]

, 2010
Background hCG is a term referring to 4 independent molecules, each produced by separate cells and each having completely separate functions. These are hCG produced by villous syncytiotrophoblast cells, hyperglycosylated hCG produced by cytotrophoblast ...
Laurence A Cole
core   +1 more source

Sonographic Predictors and Long‐Term Reproductive Outcomes in Recurrent Cesarean Scar Pregnancy

Journal of Ultrasound in Medicine, EarlyView.
Objectives To explore the ultrasound findings, treatment strategies, and reproductive outcomes in patients with recurrent cesarean scar pregnancy (CSP), providing evidence for clinical management. Methods We identified 1371 confirmed CSP from 1517 initially screened cases (2012–2022) through blinded image review. From 159 subsequent live births in this
Jianan Shi, Xiaoping Gong, Hui Wang, Tiantian Sun, Guanjie Wang, Ping Chen, Mingtao Xiong   +6 more
wiley   +1 more source

The contribution of maternal serum markers in the early prenatal diagnosis of molar pregnancies [PDF]

, 2017
The aim of this study was to evaluate the usefulness of maternal serum markers in the early prenatal diagnosis of molar pregnancies. The ultrasound features, cytogenetic and histopathological findings of 10 cases of molar pregnancy diagnosed at 11-13 ...
Bersinger, N.A., Gulbis, B., Jauniaux, E., Meuris, S.   +3 more
core  

A possible new approach in the prediction of late gestational hypertension: The role of the fetal aortic intima-media thickness [PDF]

, 2017
The aim was to determine the predictive role of combined screening for late-onset gestational hypertension by fetal ultrasound measurements, third trimester uterine arteries (UtAs) Doppler imaging, and maternal history.
Camerin, Martina, Cosmi, Erich, Grisan, Enrico, Londero, Ambrogio P., Visentin, Silvia   +4 more
core   +1 more source

UBE3A Inhibits Trophoblast Cell Migration and Invasion by Promoting ITGB1 Degradation and Affecting PI3K/AKT Signaling

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Preeclampsia (PE) is an obstetric disease that is characterized by reduced migration and invasion of placental trophoblast cells. Here, the effects of the E3 ubiquitin ligase UBE3A on the migration and invasion of trophoblast cells were evaluated.
Xiu‐Jun Li, Ning Wang, Fan Jiang, Jie‐Cheng Yang, Yan‐Yun Wang, Kun Wang   +5 more
wiley   +1 more source

Partial molar pregnancy with live fetus diagnosed on second trimester: a case report [PDF]

, 2016
Hydatidiform mole is part of a group of diseases classified as gestational trophoblastic disease, which results from an aberrant fertilization. They are associated with an increase risk for the development of neoplasm, specifically choriocarcinoma, a ...
Cardoso, Rosete Maria Amorim Novais Nogueira, Gama, Ana Paula, Pinheiro, Paula, Santos, Angela, Trocado, Vera   +4 more
core   +1 more source

Hemophilia A: An Ideal Disease for Prenatal Therapy

Prenatal Diagnosis, EarlyView.
ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada, Anthony Atala, Graça Almeida‐Porada   +2 more
wiley   +1 more source

A Rare Gestational Trophoblastic Disease: Placental Site Trophoblastic Tumor

Gynecology Obstetrics & Reproductive Medicine, 2016
Placental site trophoblastic tumor (PSTT) is a highly rare form of gestational trophoblastic diseases that arise from intermediate trophoblastic cells. By presenting this case, we aimed to review the treatment and diagnosis, approach to PSTT.
Senem Yaman Tunç, Elif Ağaçayak, Mehmet Sait İçen, Serdar Başaranoğlu, Mehmet Sıddık Evsen, Yahya Avcı, Zuhat Urakcı, Talip Gül   +7 more
doaj   +1 more source

Failure of physiologic transformation of spiral arteries, endothelial and trophoblast cell activation, and acute atherosis in the basal plate of the placenta [PDF]

, 2017
BACKGROUND: Failure of physiologic transformation of spiral arteries has been reported in preeclampsia, fetal growth restriction, fetal death, and spontaneous preterm labor with intact or ruptured membranes. Spiral arteries with failure of physiologic
Bammerlin, Elaine, Chaemsaithong, Piya, DiCarlo, Hector L., Haas, David M., Hardin, James W., Kassab, Ghassan S., Kim, Yeon Mee, Labarrere, Carlos A., Romero, Roberto   +8 more
core   +1 more source

Congenital CMV Infection: Determination of Transplacental Passage of Aciclovir by Ex Vivo Placental Perfusion

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To quantify the transplacental transfer of aciclovir at an amount equivalent to 2 g of valaciclovir corresponding to the fractionated dosing regimen given four times daily used to reduce congenital cytomegalovirus (CMV) transmission and to treat the CMV‐infected fetus. Design Experimental ex vivo study.
Helyett Ollivier, Valentine Faure Bardon, Leo Froelicher Bournaud, Isidore Gaubert, Tiffany Guilleminot, Marianne Leruez‐Ville, Jean‐Marc Treluyer, Yves Ville, Gabrielle Lui, Julien Stirnemann   +9 more
wiley   +1 more source