Annals of Neurology, EarlyView.Objective An enduring puzzle in many inherited neurological disorders is the late onset of symptoms despite expression of function‐impairing mutant protein early in life. We examined the basis for onset of impairment in spinocerebellar ataxia type 6 (SCA6), a canonical late‐onset neurodegenerative ataxia which results from a polyglutamine expansion in ...
Haoran Huang +10 more
wiley +1 more source
Prominent urinary dysfunction and delayed antibody detection in patients with glial fibrillary acidic protein astrocytopathy: a case series analysis. [PDF]
BMC NeurolNiu Z +11 more
europepmc +1 more source
Evaluation of histological and ultrastructural changes provoked by prenatal tramadol on postnatal cortical cerebellar neuronal development in rats: possible implication of Ki67, GFAP and MicroRNA-7/P53 signalling trajectories [PDF]
Walaa Adel Abdelmoez
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Intraventricular Neurilemmoma (Schwannoma): Shall GFAP Immunostaining Be Regarded as a Histogenetical Tag or as a Mere Histomimetical Trait? [PDF]
, 2016 Miguel Fernando Salazar Morales +3 more
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Annals of Neurology, EarlyView.Objective Biomarkers with clear contexts of use are important tools for amyotrophic lateral sclerosis (ALS) therapy development. Understanding their longitudinal trajectory in the untreated state is key to their use as potential markers of pharmacodynamic response.
Oleksandr Dergai +16 more
wiley +1 more source
The association of Alzheimer's disease and related dementias blood-based biomarkers with depressive symptoms. [PDF]
Alzheimers DementBacci JR +6 more
europepmc +1 more source
Astrogliosis in the GFAP-CreERT2:Rosa26iDTR Mouse Model Does Not Exacerbate Retinal Microglia Activation or Müller Cell Gliosis under Hypoxic Conditions [PDF]
Colin Rorex +7 more
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Redistribution of GFAP and αB-crystallin after thermal stress in C6 glioma cell line [PDF]
, 2006 Wei-Chia Tseng +3 more
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Endogenous Repair in Vanishing White Matter
Annals of Neurology, EarlyView.Objective Vanishing white matter is a leukodystrophy with remarkable regional variation in disease severity. The cerebral and cerebellar white matter chronically degenerates, while stress‐induced episodes of rapid neurological deterioration coincide with the appearance of acute focal lesions in the deep gray structures and brainstem.
Bonnie C. Plug +7 more
wiley +1 more source