Epilepsia, EarlyView.Abstract Objective A strong bidirectional relationship exists between epilepsy and sleep, with seizures often occurring more frequently in sleep and, in turn, sleep being disrupted by seizures. However, the mechanistic basis of seizure–sleep interactions is poorly understood.
Nicholas R. Rensing +4 more
wiley +1 more source
In vivo mapping of cortical amyloid beta-myelin coupling in preclinical Alzheimer's disease. [PDF]
Alzheimers DementAtienza M, Cantero JL.
europepmc +1 more source
An automated blood test for glial fibrillary acidic protein (GFAP) and ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) to predict the absence of intracranial lesions on head CT in adult patients with mild traumatic brain injury: BRAINI, a multicentre observational study in Europe [PDF]
Alfonso Lagares +25 more
openalex +1 more source
Long‐lasting remodeling of astrocytes in an Scna1+/− mouse model of Dravet syndrome
Epilepsia, EarlyView.Abstract Objective Dravet syndrome (DS) is a prototypical developmental and epileptic encephalopathy caused by mutations in the SCN1A gene, leading to loss of function of the voltage‐gated sodium channel Naᵥ1.1. The latter causes early onset drug‐resistant seizures and enduring cognitive and behavioral deficits.
Athénaïs Genin +10 more
wiley +1 more source
Orthopedic trauma is associated with higher serum concentrations of glial fibrillary acidic protein and ubiquitin C-terminal hydrolase L1 in mild traumatic brain injury with negative head computed tomography. [PDF]
Biochem Med (Zagreb)Osmić-Husni A, Jadrić R.
europepmc +1 more source
Effect of Ibudilast vs Placebo on GFAP and Contactin Levels in a Phase 2 Clinical Trial in Progressive Multiple Sclerosis [PDF]
Alexis Novak +4 more
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Microelectrode array scaled for human hippocampal slices
Epilepsia Open, EarlyView.Abstract Objective Temporal lobe epilepsy (TLE) is characterized by recurrent seizures originating usually from the hippocampus, and approximately one‐third of TLE patients remain refractory to pharmacological interventions. Surgical resection offers a potential cure for refractory TLE cases, with approximately 70% achieving seizure freedom. Still, the
Anssi Pelkonen +16 more
wiley +1 more source
Differential morphology and distribution of GFAP astrocytes in vocal brain circuit in a songbird Southern house wren and humans. [PDF]
Front NeuroanatHinestroza-Morales S +6 more
europepmc +1 more source
Sex differences in neurobehavior and the adult hippocampal neurogenic niche: influence of traumatic brain injury and CLIP antagonism. [PDF]
Front Behav NeurosciIannucci J +9 more
europepmc +1 more source
A case report: Diagnosis and treatment of idiopathic hypertrophic pachymeningitis
Ibrain, Volume 11, Issue 1, Page 112-116, Spring 2025.We reported a case of idiopathic hypertrophic dura meningitis diagnosed in our hospital. The patient repeatedly suffered from headaches, followed by blurred vision in the right eye. During this period, multiple sclerosis was considered for diagnosis, and it improved after hormone treatment.
Zhong Luo +7 more
wiley +1 more source