Spatial transcriptomics in epilepsy research: Early successes, opportunities, and challenges
Epilepsia, EarlyView.
Donald J. Phillips +4 more
wiley +1 more source
Near-care assay of plasma glial fibrillary acid protein and ubiquitin carboxyl-terminal hydrolase isozyme L1 with shorter and prolonged duration exercise. [PDF]
Sci RepStacey MJ +11 more
europepmc +1 more source
Expression of radial glial markers (GFAP, BLBP and GS) during telencephalic development in the catshark (Scyliorhinus canicula) [PDF]
, 2018 A. Docampo-Seara +3 more
openalex +1 more source
Focused Ultrasound for the Treatment of Circuit and Molecular Pathology in Parkinson's Disease
Movement Disorders, EarlyView.Abstract Focused ultrasound is rapidly emerging as a novel technology for the development of symptomatic therapies and supporting disease‐modifying treatments for Parkinson's disease (PD). At the forefront of this development is thermoablation using high‐intensity focused ultrasound, an incisionless treatment that has been extensively tested in ...
Rikke Hahn Kofoed +7 more
wiley +1 more source
Diet‐induced insulin resistance elevates hippocampal glutamate as well as
, 2018 Erin R. Hascup +6 more
openalex +1 more source
Parkinson's Disease Patient‐Specific Striatum Organoids Show Hallmarks of Increased Inflammation
Movement Disorders, EarlyView.Abstract Background Dopaminergic neurons from the substantia nigra pars compacta project their axons into the dorsal striatum, forming the nigrostriatal pathway. In Parkinson's disease (PD), dopaminergic terminals degenerate in the striatum, leading to dopamine depletion, which in turn causes alterations in the basal ganglia circuits that are essential
Kyriaki Barmpa +11 more
wiley +1 more source
Infection as a potential trigger in glial fibrillary acidic protein astrocytopathy: a case report and review of immunotherapeutic strategies. [PDF]
BMC NeurolZhao S, Wang Y, Li Z, Weng Q.
europepmc +1 more source
Movement Disorders, EarlyView.Abstract Background Transsynaptic α‐synuclein propagation plays a crucial role in the progression of Lewy body disease. We previously demonstrated that an α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor antagonist, perampanel, blocks neuronal uptake of α‐synuclein preformed fibrils (PFFs) in an activity‐dependent manner.
Jun Ueda +9 more
wiley +1 more source
Phytotherapy Research, EarlyView.Schematic overview of the proposed neuromodulatory actions of linalool in Alzheimer's disease. Through multi‐target effects on oxidative stress, amyloid aggregation, GABAergic and glutamatergic signaling, linalool may restore excitatory/inhibitory balance.
Ilaria Piccialli +4 more
wiley +1 more source