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Methods, 1996
The ability to direct expression of genes to astrocytes in mice has been one of the major motivators of transcriptional analyses of the glial fibrillary acidic protein (GFAP) gene. Another has been the possibility of discovering signaling pathways that operate during development, disease, and injury-all states that increase GFAP gene activity-by ...
, Brenner, , Messing
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The ability to direct expression of genes to astrocytes in mice has been one of the major motivators of transcriptional analyses of the glial fibrillary acidic protein (GFAP) gene. Another has been the possibility of discovering signaling pathways that operate during development, disease, and injury-all states that increase GFAP gene activity-by ...
, Brenner, , Messing
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NMOSD or GFAP astrocytopathy? A case report
Multiple Sclerosis and Related Disorders, 2020We describe a 43-year-old female whose manifestations fulfilled the diagnostic criteria of aquaporin-4 IgG negative neuromyelitis optica spectrum disorders (NMOSD). High titer of glial fibrillary acidic protein (GFAP) antibody was detected in cerebrospinal fluid. In this case, some symptoms pertained to NMOSD and some to GFAP antibody-related disorders.
Yue Zhang +2 more
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Glia, 2000
In the cerebellum of adult mammals, glial fibrillary acidic protein (GFAP) and vimentin (VIM) are coexpressed in Golgi epithelial cells (GEC), also known as Bergmann glia. In this study we used three transgenic knockout mice (GFAP, VIM and double GFAP and VIM) to analyze the involvement of these proteins in the building of glial filaments and in neuron-
M, Giménez Y Ribotta +3 more
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In the cerebellum of adult mammals, glial fibrillary acidic protein (GFAP) and vimentin (VIM) are coexpressed in Golgi epithelial cells (GEC), also known as Bergmann glia. In this study we used three transgenic knockout mice (GFAP, VIM and double GFAP and VIM) to analyze the involvement of these proteins in the building of glial filaments and in neuron-
M, Giménez Y Ribotta +3 more
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Microscopy Research and Technique, 2004
AbstractSensory mechanisms in teeth are not well understood and may involve pulpal–neural interactions. Tooth cells that proliferate in vitro have polyclonal immunoreactivity (IR) for glial fibrillary acidic protein (GFAP), growth‐associated protein (GAP‐43), and vimentin, plus glial‐like ion channels.
Margaret R, Byers +3 more
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AbstractSensory mechanisms in teeth are not well understood and may involve pulpal–neural interactions. Tooth cells that proliferate in vitro have polyclonal immunoreactivity (IR) for glial fibrillary acidic protein (GFAP), growth‐associated protein (GAP‐43), and vimentin, plus glial‐like ion channels.
Margaret R, Byers +3 more
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GFAP IgG associated inflammatory polyneuropathy
Journal of Neuroimmunology, 2020GFAP (glial fibrillary acidic protein)-IgG is predominantly associated with meningoencephalomyelitis, and neuropathy presentations are rare.We reviewed clinical, electrodiagnostic and histopathological presentations of GFAP-IgG associated peripheral neuropathy.We identified six cases, five of whom had peripheral neuropathy as the initial presentation ...
Pritikanta, Paul +7 more
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1999
Abstract GFAP, glial fibrilfary acidic protein, is a member of the intermediate filament protein superfamily. It is expressed almost exclusively in astrocytes of the CNS but is also found in some cells of the PNS such as non-myelinating Schwann cells. GFAP is extensively used in histology and pathology as a cell-type marker.
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Abstract GFAP, glial fibrilfary acidic protein, is a member of the intermediate filament protein superfamily. It is expressed almost exclusively in astrocytes of the CNS but is also found in some cells of the PNS such as non-myelinating Schwann cells. GFAP is extensively used in histology and pathology as a cell-type marker.
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Anaplasia and Heterogeneity of Gfap Expression in Gliomas
Tumori Journal, 1986GFAP (glial fibrillary acidic protein) distribution was investigated in selected areas of glioblastomas and astrocytomas. The proliferating cell population of glioblastomas was GFAP negative and contained many mitoses which were also negative. The old, deeply located areas were composed of cells with visible cytoplasm, intensely GFAP-positive; mitoses ...
D, Schiffer +3 more
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Clinical characteristics of autoimmune GFAP astrocytopathy
Journal of Neuroimmunology, 2019The clinical features of autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy remain to be elucidated. We describe here the clinical features of 14 patients with GFAP astrocytopathy confirmed by detection of GFAP-IgG in cerebrospinal fluid (CSF). The novel findings of this study are as follows.
Akio, Kimura +4 more
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Acta Neurologica Scandinavica, 2009
A solid-phase radioimmunoassay was developed for the detection of glial fibrillary acidic protein (GFAP) and GFAP-specific immunoglobulin G (IgG) antibodies. In antibody assays purified GFAP was absorbed onto polystyrene beads, followed by incubation in dilutions of serum.
J, Ruutiainen +4 more
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A solid-phase radioimmunoassay was developed for the detection of glial fibrillary acidic protein (GFAP) and GFAP-specific immunoglobulin G (IgG) antibodies. In antibody assays purified GFAP was absorbed onto polystyrene beads, followed by incubation in dilutions of serum.
J, Ruutiainen +4 more
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Surgical Neurology, 1991
The proliferative potential of two types of tumor cells that did or did not express glial fibrillary acidic protein (GFAP) in 19 cases of high-grade gliomas, including nine anaplastic astrocytomas (WHO criteria, grade 3) and 10 glioblastoma multiforme (grade 4), was investigated by a combined staining technique, one-step silver colloid method for ...
A, Hara +6 more
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The proliferative potential of two types of tumor cells that did or did not express glial fibrillary acidic protein (GFAP) in 19 cases of high-grade gliomas, including nine anaplastic astrocytomas (WHO criteria, grade 3) and 10 glioblastoma multiforme (grade 4), was investigated by a combined staining technique, one-step silver colloid method for ...
A, Hara +6 more
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