Results 271 to 280 of about 194,651 (386)

Reduced Plasma Aβ Peptides but Stable NfL and GFAP in Major Depressive Disorder. [PDF]

Int J Mol Sci
Fernández-Ceballos MLÁ, Vidal-Nogueira L, Fernández-Pereira C, Fortes-González P, Salgado-Barreira Á, Ledo-Matos E, Santana-Muriel E, Rivera-Baltanás T, Olivares JM, Veiga C, Prieto-González JM, Agís-Balboa RC.   +11 more
europepmc   +1 more source

Immunohistochemical characterization of the out-of frame splice variants GFAP Δ164/Δexon 6 in focal lesions associated with chronic epilepsy

, 2010
Karin Boer, Jinte Middeldorp, Wim G.M. Spliet, F. Razavi, Peter C. van Rijen, Johannes C. Baayen, Elly M. Hol, Eleonora Aronica   +7 more
openalex   +2 more sources

Xanthatin‐13‐(Pyrrolidine‐2‐Carboxylic Acid), a Sesquiterpene Lactone Isolated From Burdock Leaf, Attenuated Aβ25‐35 Toxicity and Memory Deficits in a Pharmacological Mouse Model of Alzheimer's Disease

Phytotherapy Research, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a severe form of dementia, which occurrence increases with age and lifestyle conditions. It is characterized by amyloid protein accumulation forming senile plaques, hyperphosphorylated tau protein forming neurofibrillary tangles, neuroinflammation, and oxidative stress, leading to synapse loss and cell death ...
Charlyne Barry‐Simonnet, Lucie Crouzier, Tristan Moujellil‐Legagneur, Hamza Chaieb‐Errass, Yanis A. Idres, Karine Ferrare, Marc Rolland, Guillaume Cazals, Patrick Poucheret, Tangui Maurice, Didier Tousch   +10 more
wiley   +1 more source

Microglial Activation Under Hypoxic Conditions in Early Alzheimer's Disease: Can Natural SIRT1 Activators Be Therapeutic Allies in the Inflammation–Energy Axis?

Phytotherapy Research, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative condition characterized by a preclinical stage that typically lasts for decades. Early on during this time, microglia react to pathological changes and become protective and even transiently delay neurodegeneration.
Sara Merlo, Cristiana Lucia Rita Lipari, Aurora Patti, Maria Angela Sortino   +3 more
wiley   +1 more source

Neuronal injury biomarkers GFAP and neurofilament light chains (NfL) are associated with neurotoxicity and endothelial dysfunction in adult patients treated with antiCD19 CART cells. [PDF]

Clin Exp Med
Galli E, Modoni A, Battistini L, Rossi M, Guerrera G, Pansini I, Corrente A, Hohaus S, Chiusolo P, Sorà F, Calabresi P, Sica S.   +11 more
europepmc   +1 more source

Sequential activation of microglia and astrocyte cytokine expression precedes increased iba‐1 or GFAP immunoreactivity following systemic immune challenge

Glia, 2016
Diana M. Norden, Paige J. Trojanowski, Emmanuel Villanueva, Elisa Navarro, J. Godbout   +4 more
semanticscholar   +1 more source

GFAP stained Aperio file to slide ID44082

Alex Olar
openalex   +1 more source

Glial profile in spinal cord scored with GFAP-positive cells in the dorsal horn of the lumbar tract.

, 2015
Zanardelli Matteo, Micheli Laura, C. Moreno Lorenzo, Paola Failli, Carla Ghelardini, Di Lorenzo   +5 more
openalex   +2 more sources

Spatiotemporal Co‐Delivery of Hydrogen and Magnesium via Microneedle Patches for Neuroinflammation Modulation After Spinal Cord Injury: A Multi‐Modal In Vivo Study

Small, EarlyView.
A spatiotemporal co‐delivery microneedle system (MN‐Mg) is developed for spinal cord injury repair. By generating hydrogen gas and magnesium ions in situ, this dual‐engine platform effectively scavenges ROS and modulates microglial polarization via the MAPK/AP‐1 signaling axis.
Haibo Wang, Yang Sun, Shiqi Wang, Wenbo Wang, Jincheng Tang, Ziang Li, Xinzhao Jiang, Liang Zhou, Jie Wu, Qiangqiang Guo, Yiwei Zhu, Yu Feng, Kun Xi, Liang Chen   +13 more
wiley   +1 more source

Brain Pericytes and Wnt/β‐Catenin Signaling Induce Functional Blood–Brain Barrier Phenotype in Human iPSC‐Derived Model

Small Methods, EarlyView.
This study shows that human iPSC‐derived endothelial cells acquire a functional blood–brain barrier phenotype when co‐cultured with brain pericytes and stimulated with CHIR‐99021, a Wnt/β‐catenin activator. This model recapitulates key barrier properties, inflammatory responses, and transcriptomic features of the native human BBB, offering new ...
Henrique Nogueira Pinto, Nine R. Kok, Philipp C. Hauger, Manon Karsten‐van Diepen, Michael de Kok, Nanne J. Paauw, Susanne M. A. van der Pol, Joline P. Nugteren‐Boogaard, Peter L. Hordijk, Stephanie D. Beekhuis‐Hoekstra, Susan Gibbs, Nienke M. de Wit, Helga E. de Vries   +12 more
wiley   +1 more source