Results 81 to 90 of about 127,947 (249)
Advanced Science, EarlyView.Polydopamine nanoparticles enable a precise, non‐genetic, and transcranial neuromodulation strategy via near‐infrared photothermal stimulation. By activating TRPV1 channels, this approach specifically enhances hippocampal gamma oscillations, thereby rescuing spatial memory deficits in models of perioperative neurocognitive disorder.
Yan‐Bo Zhou +10 more
wiley +1 more source
Advanced Science, EarlyView.HD‐tDCS promotes recovery after intracerebral hemorrhage by enhancing PPARγ‐dependent astrocyte remodeling in a mouse model of ICH. This process suppresses proinflammatory astrocytic activation, restores perivascular AQP4 repolarization, and improves glymphatic influx and efflux, thereby facilitating hematoma and perihematomal edema clearance and ...
Zhiming Li +8 more
wiley +1 more source
Peptide specificity test of monoclonal anti-GFAP-C6 antibodies.
, 2019 Shown are the binding of antibodies to selection-, elongated-, non-sense selection- and non-sense coater peptides of concentrations within the measuring range of each assay.
Martin Frydland (3530834) +5 more
core +1 more source
Advanced Science, EarlyView.NSD2 coordinates the neurogenic‐to‐gliogenic transition in the developing neocortex through H3K36me2‐dependent activation of EGFR–ERK signaling. Loss of NSD2 disrupts astroglial and oligodendroglial development, whereas ERK activation rescues gliogenic defects in vitro and in vivo.
Hanxue Chen +7 more
wiley +1 more source
Macroglial activity detected by GFAP- staining.
, 2016 GFAP-immunohistochemistry was used to label the macroglial cells of the retina, i.e. astrocytes and Müller cells. At 0 DIV, GFAP-staining was primarily detected in the NFL (A).
Ulrica Englund-Johansson (386818) +5 more
core +1 more source
Advanced Science, EarlyView.Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie +12 more
wiley +1 more source
reservedBackground. Le cardiopatie congenite (CHD) severe richiedono nel primo anno di vita un intervento chirurgico correttivo con bypass cardiopolmonare (CPB).
GENTILE, LORENZO
core
GFAP expression during mouse development.
, 2012 Serial sections of embryonic brains were stained with an antibody that recognizes most GFAP isoforms (pan-GFAP; B, D, F, H) or a specific GFAPδ antibody (A, C, E, G). GFAP first appeared at E12 (B) whereas GFAPδ was absent at E12 and E15 (A and C).
Carlyn Mamber (109999) +5 more
core +1 more source
Endothelial YAP Signaling Promotes Blood‐Spinal Cord Barrier Repair in Mice After Spinal Cord Injury
Advanced Science, EarlyView.Endothelial YAP is required for blood‐spinal cord barrier repair after spinal cord injury. YAP‐dependent vascular repair is associated with ANGPT1/PI3K/AKT signaling in vivo and may involve endothelial‐pericyte paracrine interactions. By supporting vascular remodeling, tight junction restoration, restored pericyte coverage, and astrocyte‐vascular ...
Jiawei Wang +14 more
wiley +1 more source
Neurostatin alone reduces GFAP expression.
, 2013 C57BL/6 mice (n = 6) were treated by intravitreal injection of PBS, KA (10 nM), or KA plus Neurostatin (5 mM). At 24, 48 and 72 h after injection, retinal flat mounts were immunostained with antibodies against GFAP (top panel) and retinal cross sections (
Bhagyalaxmi S. Ganesh (353895) +1 more
core +1 more source