Results 31 to 40 of about 93,938 (325)
Physiological Effect of Ghrelin on Body Systems
International Journal of Endocrinology, 2020 Ghrelin is a relatively novel multifaceted hormone that has been found to exert a plethora of physiological effects. In this review, we found/confirmed that ghrelin has effect on all body systems. It induces appetite; promotes the use of carbohydrates as
Yonas Akalu +3 more
semanticscholar +1 more source
The oncogenic role of the In1-ghrelin splicing variant in prostate cancer aggressiveness
Molecular Cancer, 2017 Background The Ghrelin-system is a complex, pleiotropic family composed of several peptides, including native-ghrelin and its In1-ghrelin splicing variant, and receptors (GHSR 1a/b), which are dysregulated in various endocrine-related tumors, where they ...
Daniel Hormaechea-Agulla +18 more
doaj +1 more source
Hindbrain ghrelin receptor signaling is sufficient to maintain fasting glucose. [PDF]
PLoS ONE, 2012 The neuronal coordination of metabolic homeostasis requires the integration of hormonal signals with multiple interrelated central neuronal circuits to produce appropriate levels of food intake, energy expenditure and fuel availability.
Michael M Scott +8 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 The role of high-fat diet (HFD) induced gut microbiota alteration and Ghrelin as well as their correlation in benign prostatic hyperplasia (BPH) were explored in our study. The gut microbiota was analyzed by 16s rRNA sequencing.
Meng Gu +7 more
doaj +1 more source
Changes in subcellular distribution of n-octanoyl or n-decanoyl ghrelin in ghrelin-producing cells
Frontiers in Endocrinology, 2013 Background: The enzyme ghrelin O-acyltransferase (GOAT) catalyzes the acylation of ghrelin. The molecular form of GOAT, together with its reaction in vitro, has been reported previously.
Yoshihiro eNishi +8 more
doaj +1 more source
Altered lipid and salt taste responsivity in ghrelin and GOAT null mice. [PDF]
PLoS ONE, 2013 Taste perception plays an important role in regulating food preference, eating behavior and energy homeostasis. Taste perception is modulated by a variety of factors, including gastric hormones such as ghrelin. Ghrelin can regulate growth hormone release,
Huan Cai +7 more
doaj +1 more source
International Journal of Peptides, 2010 Rikkunshito is a popular Japanese traditional medicine that is prescribed in Japan to treat various gastrointestinal tract disorders. In a double-blind controlled study, rikkunshito significantly ameliorated dysmotility-like dyspepsia and brought about a generalized improvement in upper gastric symptoms such as nausea and anorexia when compared with a ...
openaire +3 more sources
Insights from engraftable immunodeficient mouse models of hyperinsulinaemia
Scientific Reports, 2017 Hyperinsulinaemia, obesity and dyslipidaemia are independent and collective risk factors for many cancers. Here, the long-term effects of a 23% Western high-fat diet (HFD) in two immunodeficient mouse strains (NOD/SCID and Rag1 −/−) suitable for ...
Michelle L. Maugham +11 more
doaj +1 more source
Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery.
New England Journal of Medicine, 2002 BACKGROUND Weight loss causes changes in appetite and energy expenditure that promote weight regain. Ghrelin is a hormone that increases food intake in rodents and humans.
D. Cummings +6 more
semanticscholar +1 more source
Structure of an antagonist-bound ghrelin receptor reveals possible ghrelin recognition mode
Nature Communications, 2020 Ghrelin is a gastric peptide hormone with important physiological functions. The unique feature of ghrelin is its Serine 3 acyl-modification, which is essential for ghrelin’s activity.
Y. Shiimura +10 more
semanticscholar +1 more source