Results 61 to 70 of about 38,787 (232)
Central but not systemic administration of ghrelin induces wakefulness in mice. [PDF]
PLoS ONE, 2012 Ghrelin is a brain-gut peptide hormone widely known for its orexigenic and growth hormone-releasing activities. Findings from our and other laboratories indicate a role of ghrelin in sleep regulation.
Éva Szentirmai
doaj +1 more source
GDF15 Is Elevated in Eating Disorders and Is Involved in the Gut‐Brain Axis via Ghrelin
European Eating Disorders Review, EarlyView.ABSTRACT Objective GDF15 induces anorexia and visceral discomfort, regulating appetite, food intake and potentially metabolic responses. However, its role in eating disorders remains unexplored. Method A total of 145 participants were recruited (60 patients with anorexia nervosa, 20 with bulimia nervosa, 13 with binge eating disorder, 52 participants ...
Livio Tarchi +14 more
wiley +1 more source
Expression of Serum Retinol Binding Protein and Transthyretin within Mouse Gastric Ghrelin Cells. [PDF]
PLoS ONE, 2013 Ghrelin is an orexigenic peptide hormone produced mainly by a distinct group of dispersed endocrine cells located within the gastric oxyntic mucosa. Besides secreted gene products derived from the preproghrelin gene, which include acyl-ghrelin, desacyl ...
Angela K Walker +4 more
doaj +1 more source
Food Frontiers, EarlyView.ABSTRACT Oat bran (OB), a byproduct of the oat milling process, is a nutrient‐dense cereal cultivated in cool, dry mountainous regions and is known for its potential health benefits. To explore its obesity‐alleviating effects and the underlying mechanisms, we examined the influence of OB on glucose metabolism, appetite‐regulating hormones, gut ...
Xue Bai +6 more
wiley +1 more source
Ghrelin and vascular protection [PDF]
Vascular Biology, 2019 Ghrelin is a small peptide with important roles in the regulation of appetite, gut motility, glucose homeostasis as well as cardiovascular protection. This review highlights the role that acyl ghrelin plays in maintaining normal endothelial function by maintaining the balance of vasodilator-vasoconstrictor factors, inhibiting inflammatory cytokine ...
Rajesh Katare +8 more
openaire +4 more sources
Frontiers in Endocrinology, 2015 Ghrelin is a 28 amino-acid hormonal peptide that is intimately related to the regulation of food intake and body weight. Once secreted, ghrelin binds to the growth hormone secretagogue receptor-1a (GHSR-1a), the only known receptor for ghrelin and is ...
Martin K Wellman +7 more
doaj +1 more source
iMeta, EarlyView.scRiskCell is an interpretable intelligent computational framework that leverages nearly 500,000 islet cell expression profiles from 106 donors across different continuous disease states. By calculating the intrinsic relationship between donor disease states and cell expression profiles, it assigns a pseudo‐cell state index to each cell.
Xueqin Xie +7 more
wiley +1 more source
Ghrelin and reproductive disorders [PDF]
Molecular and Cellular Endocrinology, 2011 Ghrelin is an important factor involved in most of the metabolic and hormonal signals which adapt the reproductive functions in conditions of altered energy balance. Moreover, the coordinated role of leptin and ghrelin appears in fact to have a specific role in the regulation of puberty.
REPACI, ANDREA +3 more
openaire +5 more sources
Journal of Clinical Laboratory Analysis, EarlyView.In this study, we aimed for the first time to demonstrate biotin interference in ELISA research kits used in the analysis of pediatric obesity parameters other than routine testing. Our study revealed that biotin interaction may occur in manual ELISA kits and may cause erroneous test results.
Ezgi Kürkçü Kahraman +4 more
wiley +1 more source
Ghrelin in Central Neurons [PDF]
Current Neuropharmacology, 2009 Ghrelin, an orexigenic peptide synthesized by endocrine cells of the gastric mucosa, is released in the bloodstream in response to a negative energetic status. Since discovery, the hypothalamus was identified as the main source of ghrelin in the CNS, and effects of the peptide have been mainly observed in this area of the brain.
FERRINI, Francesco Maria +3 more
openaire +4 more sources