Results 71 to 80 of about 47,706 (229)

Frequent Versus Single Active Bouts Differentially Affect Movement Behavior and Energy Balance in Adults With Overweight/Obesity

Obesity, EarlyView.
ABSTRACT Objective This study aimed to investigate the effects of breaking up sedentary behavior (SB) on daily movement behavior and energy balance in adults with overweight/obesity. Methods Thirty participants (16F/14M; 34.2 ± 7.3 years; 29.5 ± 3.2 kg/m2) were randomized to either BREAK (multiple 5‐min brisk walking bouts) or a duration‐matched ...
Heloisa C. Santo Andre, Elisa Le Roux, Nathan P. De Jong, Patricia R. Smith, Andrew H. Lange, Carlos Mendez, Alexandre Zahariev, Melissa L. Mamele, Ginger Johnson, Zhaoxing Pan, Chantal Simon, Daniel H. Bessesen, Ana J. Pinto, Audrey Bergouignan   +13 more
wiley   +1 more source

A re-examination of the Ghrelin and Ghrelin receptor genes [PDF]

, 2009
The last few years have seen dramatic advances in genomics, including the discovery of a large number of non-coding and antisense transcripts. This has revolutionised our understanding of multifaceted transcript structures found within gene loci and ...
Seim, Inge
core   +1 more source

IgG Anti-ghrelin Immune Complexes Are Increased in Rheumatoid Arthritis Patients Under Biologic Therapy and Are Related to Clinical and Metabolic Markers

Frontiers in Endocrinology, 2019
Rheumatoid arthritis (RA) is a systemic autoimmune disease associated with increased risk of cardiovascular disease and metabolic alterations. The mechanisms underlying these alterations remain unclear.
Mildren Porchas-Quijada, Zyanya Reyes-Castillo, José Francisco Muñoz-Valle, Sergio Durán-Barragán, Sergio Durán-Barragán, Virginia Aguilera-Cervantes, Antonio López-Espinoza, Mónica Vázquez-Del Mercado, Mónica Navarro-Meza, Patricia López-Uriarte   +9 more
doaj   +1 more source

Sodium Ions Affect GPR17 Conformational States and Functionality

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Sodium is an allosteric modulator of several class‐A GPCR regulating active versus inactive conformation state and may be a critical issue for the optimization of crystallization procedures. Herein, the role of Na+ in the regulation of GPR17 conformational states was studied through MD simulations of GPR17 wild‐type and mutated on two ...
Luca Palazzolo, Simona Daniele, Davide Bianchi, Lara Russo, Stefano Capaldi, Maria Letizia Trincavelli, Ivano Eberini   +6 more
wiley   +1 more source

Análise imunoistoquímica quantitativa das células de grelina duodenais após gastrectomia vertical em ratos Wistar [PDF]

, 2013
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Ciências Médicas, Florianópolis, 2013Introdução: A obesidade é um problema de saúde pública de âmbito global. A obesidade é multifatorial
Teive, Marcelo Bianchini
core  

Multi-species sequence comparison reveals conservation of ghrelin gene-derived splice variants encoding a truncated ghrelin peptide [PDF]

, 2016
The peptide hormone ghrelin is a potent orexigen produced predominantly in the stomach. It has a number of other biological actions, including roles in appetite stimulation, energy balance, the stimulation of growth hormone release and the regulation of ...
Seim, Inge, Whiteside, Eliza J., Herington, Adrian C., Seim, I, Yap, PY, Jeffery, PL, O'Keeffe, Angela J., Chopin, LK, Jeffery, Penny L., Thomas, Patrick B., Lai, J, Maugham, M, Whiteside, EJ, Lai, John, Yap, Pei-Yi, Chopin, Lisa K., O’Keeffe, AJ, Walpole, CM, Walpole, Carina M., Fung, Jenny N.T., O’Keeffe, Angela J., Thomas, PB, Fung, JNT, Maugham, Michelle, Fung, Jenny N. T., Herington, AC   +25 more
core   +2 more sources

Sensing of fatty acids for octanoylation of ghrelin involves a gustatory G-protein. [PDF]

PLoS ONE, 2012
BackgroundGhrelin is an important regulator of energy--and glucose homeostasis. The octanoylation at Ser(3) is essential for ghrelin's biological effects but the mechanisms involved in the octanoylation are unknown.
Sara Janssen, Jorien Laermans, Hiroshi Iwakura, Jan Tack, Inge Depoortere   +4 more
doaj   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists in Pregnancy: Periconception Exposure and Perinatal Outcomes

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective An increasing number of women of childbearing age worldwide are using glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and are advised to use effective contraception during treatment. Nevertheless, maternity services are encountering increasing numbers of women exposed to GLP‐1 RAs shortly before conception or during pregnancy ...
Katherine G. Y. Lau, Anisha Chopra, Edward Mullins, Rochan Agha‐Jaffar, Tricia Tan, Lynne Sykes, Christina K. H. Yu   +6 more
wiley   +1 more source

Effect of Social Rank on Gut Microbes and Their Metabolites of Greater Long‐Tailed Hamsters (Tscherskia triton)

Integrative Zoology, EarlyView.
Social rank in greater long‐tailed hamsters (Tscherskia triton) shapes gut microbiota composition and metabolite profiles. Dominant males exhibit a “high‐vigilance, metabolically activated” phenotype, with elevated aggression and specific gut microbiota enriched in energy‐harvesting taxa and fecal queuine.
Da Zhang, Xiaoming Xu, Zhibin Zhang
wiley   +1 more source

Avaliação da expressão imuno-histoquímica das células retais produtoras de grelina em ratos Wistar submetidos à dieta de cafeteria [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Ciências Médicas, Florianópolis, 2012Introdução: Na atualidade o sobrepeso e a obesidade, induzidos pela dieta e pelo sedentarismo,
Lyra Junior, Humberto Fenner
core