Results 91 to 100 of about 31,273 (172)

Multi‐Omics Profiling Reveals Immunomodulatory and Pro‐Regenerative Effects of a Graphene Oxide–Collagen Scaffold in Massive Rotator Cuff Tears

Advanced Science, Volume 13, Issue 44, 7 August 2026.
A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan, Yechuan Deng, Zixin Hu, Yanwei He, Xinting Feng, Jun Ma, Yisheng Chen, Zhijie Zhao, Jie Mei, Zhiheng Lin, Wei Luo, Zhengyuan Fang, Zhufeng Hu, Kunlun Feng, Xinrong Li, Dan Wu, Bowen Han, James Hoi po Hui, Xuanyong Liu, Chen Chen, Gang Chen, Shiyi Chen, Nirong Bao, Jiajun Qiu, Zhiwen Luo   +24 more
wiley   +1 more source

The Mechanobiology of Adipocyte Hypertrophy: Cytoskeletal Remodelling as a Driver of Insulin Resistance in Obesity

Cell Biochemistry and Function, Volume 44, Issue 8, August 2026.
ABSTRACT Adipocyte hypertrophy poses an important mechanical challenge—adipocytes can increase in volume up to a thousand‐fold while still maintaining their structural integrity. Although lipid metabolism is well studied, little is known about the cytoskeletal adaptations that are required to accommodate this expansion and the resulting pathological ...
Dhakshmi Sasankan, Renu Mohan
wiley   +1 more source

A Prospective Observational Study of Anamorelin During Chemoimmunotherapy in Non‐Small Cell Lung Cancer With Cachexia (SPIRAL‐ANA)

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background The prognosis of patients with advanced non‐small cell lung cancer (NSCLC) complicated by cancer cachexia remains poor. Anamorelin, a ghrelin receptor agonist, has been approved only in Japan for the treatment of cancer cachexia.
Kenji Morimoto, Junji Uchino, Makoto Hibino, Yuki Takeyasu, Ken Yamamoto, Yoshie Morimoto, Yusuke Chihara, Takayuki Nakano, Hiroyasu Kaneda, Shunya Tanaka, Shinsuke Ogusu, Yasuhiro Goto, Takashi Nomizo, Takayo Ota, Hiroaki Tsukamoto, Yoshizumi Takemura, Katsumi Nakatomi, Hayato Koba, Kohei Yoshimine, Takayuki Shimose, Tadaaki Yamada, Koichi Takayama   +21 more
wiley   +1 more source

Interventions for Unhealthy Eating Patterns of Resident Otolaryngologists on Call

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 4, August 2026.
ABSTRACT Objectives Resident physicians commonly experience elevated stress levels and disrupted sleep while on call. Many also report intense cravings for comfort food, typically high in fat, sugar, and salt. The objective of this pilot study was to explore the physiological and psychological factors contributing to the desire for unhealthy food among
Hannah G. Luk, Harold Pine
wiley   +1 more source

Changes in Ultra‐Processed Food Intake During a Single‐Arm Behavioral Weight Management Intervention: A Secondary Analysis

Obesity, Volume 34, Issue 8, Page 1592-1599, August 2026.
ABSTRACT Objective Increasing evidence links ultra‐processed food (UPF) intake to obesity and related diseases; however, little is known about the role of UPF in behavioral weight‐loss interventions (BWLIs). Thus, the current study investigated whether UPF intake changes during a BWLI and whether these changes are associated with weight‐loss outcomes ...
Kate E. Worwag, Armaan Shetty, Meena N. Shankar, Kathryn M. Ross   +3 more
wiley   +1 more source

Desire to Weigh Less and Unhealthy Weight Control Behaviors Among U.S. Adults: Evidence From NHANES 2017–2018

Obesity Science &Practice, Volume 12, Issue 4, August 2026.
ABSTRACT Background With obesity rates remaining high in the United States, many individuals attempt weight loss using self‐directed approaches that may not align with clinical recommendations. Objective This secondary data analysis examines the association between a desire to weigh less and unhealthy weight control behaviors among American adults ...
Anna V. Garcia, Elizabeth Dodge, Basil H. Aboul‐Enein   +2 more
wiley   +1 more source

Alcohol Exposure Alters the Ghrelin System: In Vitro Mechanistic Insights Into Impaired Glucose Sensing and Enhanced Ghrelin Secretion

Alcohol, Clinical and Experimental Research, Volume 50, Issue 8, August 2026.
Chronic ethanol exposure increases ghrelin production by impairing glucose sensing in ghrelin‐secreting cells. Ethanol elevates ghrelin and ghrelin O‐acyltransferase expression, blunts glucose‐mediated suppression, and synergizes with fatty acids to enhance secretion.
Sundararajan Mahalingam, Ramesh Bellamkonda, Kusum K. Kharbanda, Ojeshvi Ethiraj, Carol A. Casey, Karuna Rasineni   +5 more
wiley   +1 more source

Intragastric Balloon Treatment Enhances Weight Maintenance Adjunct to Low‐Energy Diet and Group‐Based Cognitive Behavioural Therapy: A Randomized Controlled Trial

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 7300-7311, August 2026.
ABSTRACT Aims Low‐energy diet (LED) plus cognitive‐behavioural therapy (CBT) produces substantial short‐term weight loss in obesity, but long‐term maintenance remains difficult. We evaluated whether adding intragastric balloon (IGB) treatment to group‐based CBT improves weight maintenance after initial weight loss using LED.
Marije Galavazi, Qays Shahed, Hugo Hesser, Yang Cao, Stefan Jansson, Michiel van Nieuwenhoven, Johan Jendle   +6 more
wiley   +1 more source

Investigating the Incremental Cost and Utilization Burden of Obstructive Sleep Apnea in Overweight to Severely Obese Patients

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 7517-7526, August 2026.
ABSTRACT Aims To quantify the incremental economic and utilization burden of comorbid obstructive sleep apnea (OSA) within an overweight to severely obese adult population. Material and Methods This retrospective cohort study utilized 2016–2025 IQVIA PharMetrics Plus Closed Health Plan commercial claims data to identify overweight to severely obese ...
Hyung Seok John Kim, Tien Hoang Tran, Christopher N. Schmickl, Julia F. Slejko   +3 more
wiley   +1 more source

Shared Behavioural Determinants of Short Sleep and Obesity From Childhood to Adolescence: An Analyses of Growing Up in Scotland Birth Cohort 1

Pediatric Obesity, Volume 21, Issue 8, August 2026.
ABSTRACT Background Previous research shows a longitudinal relationship between poor sleep and obesity in adolescents, highlighting the need to identify shared modifiable determinants to strengthen health‐promoting interventions. The aim of this study was to investigate the determinants at 10 and 12 years associated with short sleep and body mass index
Emma Louise Gale, Joanne Elizabeth Cecil, Andrew James Williams   +2 more
wiley   +1 more source