Results 101 to 110 of about 47,706 (229)

Cloning of a novel insulin-regulated ghrelin transcript in prostate cancer [PDF]

, 2012
Free to read\ud \ud Ghrelin is a multifunctional hormone, with roles in stimulating appetite and regulating energy balance, insulin secretion and glucose homeostasis.
Seim, Inge, Lehman, Melanie L., Whiteside, Eliza J., Herington, Adrian C., Chopin, Lisa K., Lehman, Melanie, Lubik, Amy A., Tomlinson, Nadine, Whiteside, Eliza, Nelson, Colleen C.   +9 more
core   +2 more sources

Daridorexant‐ Case Report of Possible Side‐Effect in Rare Mitochondrial Disorder

Journal of Sleep Research, EarlyView.
ABSTRACT This case report describes a 40‐year‐old woman with maternally inherited diabetes and deafness (MIDD), a rare mitochondrial disorder, who received treatment with daridorexant due to severe chronic insomnia. She developed progression of her MIDD symptoms during treatment.
Sven Svedmyr, Joel Bergqvist
wiley   +1 more source

Cardiovascular activities of ghrelin and synthetic GHS

, 2004
Recent experimental data demonstrate cardiovascular effects of synthetic growth hormone secretagogues (GHS). These cardiovascular effects include improvement of systolic function in rats after experimental infarction, cardioprotection against ...
Tivesten, Åsa,, Johansson, Inger,, Isgaard, Jörgen,   +2 more
core  

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source

Effects of Feeding Pattern on Plasma Ghrelin Concentrations in Pigs

, 2005
The independent role of ghrelin regulation continues to be controversial. Ghrelin, a 28 amino acid peptide identified as the endogenous ligand for growth hormone (GH) secretoagogue receptor, is found in the gastrointestinal tract, predominantly the ...
Brown, Caroline Elizabeth
core  

Established and Emerging Biomarkers to Characterize Persons at Risk for Obesity—Paving the Way for Targeted Clinical Intervention Trials—A Comprehensive Position Paper

Obesity Reviews, EarlyView.
ABSTRACT Despite all efforts, obesity remains a major health concern worldwide, with continuously increasing rates, affecting approx. 14% of the total world population, being as high as 43% in some countries. As obesity is related to numerous comorbidities, including type 2 diabetes, cardiovascular diseases, and some types of cancer, the consequences ...
Farhad Vahid, Victoria Stopa, Laurent Malisoux, Yvan Devaux, Elsa Lamy, Fernando Capela e Silva, Sarah Forberger, Tiziana de Magistris, Antoni Sureda, Margalida Monserrat‐Mesquida, Maria Pérez‐Jiménez, Rajini Nagrani, Maria Giovanna Onorati, Michele Filippo Fontefrancesco, Jonathan Turner, Mahesh S. Desai, Josep Tur, Cristina Bouzas, Gino Gabriel Bonetti, Oliver Riedel, Gitte Ravn‐Haren, Rikke Andersen, Torsten Bohn   +22 more
wiley   +1 more source

Ghrelin-related peptides exert protective effects in the cerebral circulation of male mice through a nonclassical ghrelin receptor(s)

, 2015
The ghrelin-related peptides, acylated ghrelin, des-acylated ghrelin, and obestatin, are novel gastrointestinal hormones. We firstly investigated whether the ghrelin gene, ghrelin O-acyltransferase, and the ghrelin receptor (GH secretagogue receptor 1a ...
Chris Sobey (19981698), Jacqueline Ku (10922585), Mark Sleeman (20037516), Z.B Andrews (20028033), Tom Barsby (238546), M Lemus (13636768), A Reichenbach (13608268), Sarah Spencer (18025435), Alyson Miller (3436901), Grant Drummond (13349100)   +9 more
core  

Ghrelin transport across the blood–brain barrier can occur independently of the growth hormone secretagogue receptor

Molecular Metabolism, 2018
Objective: The blood–brain barrier (BBB) regulates the entry of substrates and peptides into the brain. Ghrelin is mainly produced in the stomach but exerts its actions in the central nervous system (CNS) by crossing the BBB.
Elizabeth M. Rhea, Therese S. Salameh, Sarah Gray, Jingjing Niu, William A. Banks, Jenny Tong   +5 more
doaj   +1 more source

Investigating Overweight and Obesity Risk in Shift Workers Using Omics Technologies

Obesity Reviews, EarlyView.
ABSTRACT Night shift workers are at higher risk of developing overweight and obesity. The disruption of the physiological circadian rhythm leads to metabolic alterations, such as decreased insulin sensitivity, increased adipogenesis, and inflammation, with effects on their health and leading, among other diseases, to obesity.
Katrin Scionti, Ivana Václavková, Vanessa Schoissengeier, Karl‐Heinz Wagner   +3 more
wiley   +1 more source

Ghrelin mimics fasting to enhance human hedonic, orbitofrontal cortex, and hippocampal responses to food

, 2014
Background: Ghrelin, which is a stomach-derived hormone, increases with fasting and energy restriction and may influence eating behaviors through brain hedonic reward-cognitive systems.
Beckmann, C., Chhina, N., Miras, A.D., Frost, G.S., Bloom, S.R., Goldstone, A.P., Bell, J.D., Scholtz, S., Durighel, G., Gaylinn, B.D., Waldman, A.D., Prechtl, C.G., Deliran, S.S., Ghatei, M.A., Ashby, D.R., Thorner, M.O.   +15 more
core   +1 more source