Results 111 to 120 of about 43,755 (242)

The Duodenal Mucosa Plays a Key Role in Metabolic Regulation: Emerging Physiology and New Opportunities for Cell‐Directed and Barrier‐Related Interventions for the Treatment of Diabetes and Obesity

Diabetes, Obesity and Metabolism, Volume 28, Issue S3, Page 3-15, June 2026.
ABSTRACT The duodenum has historically been regarded as a passive digestive conduit for nutrient transit and absorption. However, emerging experimental and clinical evidence supports a revision of this view. In a contemporary model, the proximal small intestine also has roles as a metabolic sensor and endocrine signalling hub that exerts a powerful ...
David A. D’Alessio, Jonathan E. Campbell   +1 more
wiley   +1 more source

Exploring the Potential of Calebin‐A in Targeting Obesity‐Related Genes and Pathways

Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Obesity is a global health crisis affecting millions, associated with metabolic disorders such as type 2 diabetes and cardiovascular disease. Calebin‐A, a bioactive compound derived from Curcuma species, has shown promise in managing obesity and its complications.
Ali Mahmoudi, Ali Saeedi‐Boroujeni, Sercan Karav, Prashant Kesharwani, Amirhossein Sahebkar   +4 more
wiley   +1 more source

Adaptation of ghrelin and the GH/IGF axis to high altitude [PDF]

, 2012
Stefan Riedl, Michael Kluge, Katharina Schweitzer, Thomas Waldhör, H Frisch   +4 more
openalex   +1 more source

Effect of Time‐Restricted Eating on Metabolic Adaptation in Adults With Severe Obesity During Early Phase of Weight Loss

Journal of Human Nutrition and Dietetics, Volume 39, Issue 3, June 2026.
ABSTRACT Objective To compare metabolic adaptations at the early phase of weight loss in individuals with severe obesity assigned to two strategies of energy restriction: continuous or in combination with time‐restricted eating (TRE). Methods 100 participants (> 40 kg/m2; 20–60 years) were randomized into two groups: continuous energy restriction (CER,
Tatiana Almeida de Moraes Campos, Raiane Lira Freitas Brasil, Flávia Fioruci Bezerra   +2 more
wiley   +1 more source

Electroacupuncture Upregulated Ghrelin in Rats with Functional Dyspepsia via AMPK/TSC2/Rheb-Mediated mTOR Inhibition [PDF]

, 2019
Lei Tang, Yi Zeng, Lei Li, Jingjing Wang, Duo Peng, Ting Zhang, Hongxing Zhang, Xue An   +7 more
openalex   +1 more source

Involvement of ghrelin in the regulation of swallowing motor activity in an arterially perfused rat preparation

, 2022
Mitsunori Ishiguro, Kiyomi Nakayama, Shiro Nakamura, Ayako Mochizuki, Masanori Dantsuji, Yoshiaki Ihara, Tomio Inoue   +6 more
openalex   +1 more source

Role of Ghrelin in the Pathophysiology of Gastrointestinal Disease

Gut and Liver, 2013
Ghrelin is a 28-amino-acid peptide that plays multiple roles in humans and other mammals. The functions of ghrelin include food intake regulation, gastrointestinal (GI) motility, and acid secretion by the GI tract.
doaj   +1 more source

Associations of PYY, GLP‐1 and LEAP2 with changes in feeding‐related cognition, body weight and glucose homeostasis after bariatric surgery in non‐diabetic women

Journal of Neuroendocrinology, Volume 38, Issue 6, June 2026.
Abstract Roux‐en‐Y gastric bypass (RYGB) is an effective surgical intervention for severe obesity, but the role of gastrointestinal hormones in its benefits remains unclear. We examined longitudinal pre‐to‐post‐meal gastrointestinal hormone changes and their relationships with glucose homeostasis and feeding‐related cognitive responses in women ...
María F. Andreoli, Pablo N. De Francesco, Wei Zhou, Olga E. Titova, Ahmed Alsehli, Robert Fredriksson, Magnus Sundbom, Mario Perello, Helgi B. Schiöth   +8 more
wiley   +1 more source

Molecular mechanisms behind ghrelin-mediated prevention of post-surgical adhesions [PDF]

, 2016
Enrica Bianchi, Kim Boekelheide, Mark Sigman, Susan J. Hall, Kevin Hwang   +4 more
openalex   +1 more source

Longitudinal and Bidirectional Relationships Between Sleep, Emotional Wellbeing and Weight Status in Childhood and Adolescence: Growing Up in Scotland Cohort Analysis

Journal of Sleep Research, Volume 35, Issue 3, June 2026.
ABSTRACT Poor sleep and emotional wellbeing, which often decline during puberty, are associated with declines in metabolic health and are key determinants of childhood obesity. The aim of the study was to explore bidirectional associations between sleep, emotional wellbeing and obesity from ages 8 to 14 using the Growing Up in Scotland cohort ...
Emma Louise Gale, Joanne Elizabeth Cecil, Andrew James Williams   +2 more
wiley   +1 more source