Results 71 to 80 of about 30,314 (188)

Effects of sodium octanoate, acylated ghrelin, and desacylated ghrelin on the growth of genetically engineered escherichia coli [PDF]

open access: yesJournal of Medical Biochemistry, 2011
Acylated ghrelin is a 28-amino acid peptide hormone bearing a fatty acid group based on octanoic acid (caprylic acid) at the serine which is located at position 3 and at the N-terminus.
Aydin Suleyman   +2 more
doaj  

Distribution of ghrelin-positive mast cells in rat stomach

open access: yesBiotechnology & Biotechnological Equipment, 2017
It is known that the gastrointestinal peptide hormone ghrelin is expressed in human and rodent B lymphocytes, T lymphocytes, monocytes and natural killer cells. However, there are no data about ghrelin expression by mast cells.
Ivaylo Stefanov Stefanov   +5 more
doaj   +1 more source

Analysis of Ghrelin and Asymmetric Dimethylarginine (ADMA) as Endothelial Dysfunction Marker Among Obese Men

open access: yesIndonesian Biomedical Journal, 2012
BACKGROUND: Ghrelin has many biological activities such as regulating energy homeostasis and recent studies have shown its effects in the cardiovascular system.
Lia Meliani   +2 more
doaj   +1 more source

The Role of the Oral Microbiome in Circulating Metabolic Biomarkers and the Influence of Air Pollution

open access: yesOral Diseases, EarlyView.
ABSTRACT Aims The oral microbiome is at the frontline for environmental exposure and plays an important role in human metabolism. This study explores the relationship between PM2.5 exposure, the oral microbiome, and metabolic biomarkers including ghrelin, resistin, and insulin.
Jiajun Luo   +5 more
wiley   +1 more source

The role of agomelatine in appetite regulation and body weight in rats

open access: yesExperimental Physiology, EarlyView.
Abstract The hypothalamic nuclei play a central role in the synthesis of anorexigenic and orexigenic neuropeptides, which are regulated by peripheral hormones, like leptin and ghrelin. Melatonergic receptors (MT1/MT2) are prominently expressed in the arcuate nucleus of the hypothalamus – an essential hub for appetite control – and in peripheral ...
Engin Korkmaz   +3 more
wiley   +1 more source

Ghrelin transport across the blood–brain barrier can occur independently of the growth hormone secretagogue receptor

open access: yesMolecular Metabolism, 2018
Objective: The blood–brain barrier (BBB) regulates the entry of substrates and peptides into the brain. Ghrelin is mainly produced in the stomach but exerts its actions in the central nervous system (CNS) by crossing the BBB.
Elizabeth M. Rhea   +5 more
doaj   +1 more source

Ghrelin protects against cell death in myocardial ischaemia: Emerging role of microRNA

open access: yesExperimental Physiology, EarlyView.
Abstract Acute myocardial infarction (MI) accelerates cardiomyocyte apoptosis, which underpins ventricular remodelling and dysfunction. The hormone ghrelin mitigates this remodelling, but the mechanisms remain unclear. Specific microRNAs (miRs) are key modulators and reliable biomarkers of early‐stage apoptosis.
Rajesh Katare   +2 more
wiley   +1 more source

Reduced cardiovascular mortality at moderate altitude: a putative role of physical activity and body mass

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Benefits of performing physical exercise at moderate altitude. At moderate altitude, increased resting metabolic rate and physical exertion promote physical fitness and exercise tolerance, whereas hypoxia suppresses appetite and elicits adaptations that increase tissue O2 delivery while augmenting O2‐independent ATP production ...
Robert T. Mallet   +6 more
wiley   +1 more source

GHRELIN AMELIORATES WASTING, CARDIOVASCULAR COMPLICATIONS, INFLAMMATION AND MORTALITY IN CHRONIC KIDNEY DISEASE

open access: yesKidney Research and Clinical Practice, 2012
Wasting, cardiovascular complications and inflammation are known risk factors associated with high mortality in patients with chronic kidney disease (CKD).
Robert Mak   +6 more
doaj   +1 more source

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

open access: yesComprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu   +11 more
wiley   +1 more source

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