Results 71 to 80 of about 1,268,458 (245)

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Relationship of Ghrelin and Ghrelin Receptor Polymorphisms with Type 2 Diabetes

, 2022
There is compelling evidence that the gastric peptide ghrelin and its growth hormone secretagogue G protein-coupled receptor play an important role in glucose metabolism and energy homeostasis. Therefore, these genes carrying susceptibility alleles for Type 2 diabetes are considered as potential candidates.A case-control cross-sectional association ...
Özkahraman, Didem, Selçuk, Esma, Şahin Calapoğlu, Nilüfer, Calapoğlu, Mustafa, Şahin, Uğur   +4 more
openaire   +3 more sources

Central neuropeptide Y receptors are involved in 3^rd ventricular ghrelin induced alteration of colonic transit time in conscious fed rats

BMC Gastroenterology, 2005
Background Feeding related peptides have been shown to be additionally involved in the central autonomic control of gastrointestinal functions. Recent studies have shown that ghrelin, a stomach-derived orexigenic peptide, is involved in the autonomic ...
Ritter Michael, Mronga Silke, Tebbe Clemens G, Tebbe Johannes J, Schäfer Martin KH   +4 more
doaj   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

The ghrelin receptor isoforms (GHS-R1a and GHS-R1b) and GPR39 : an investigation into receptor dimerisation [PDF]

, 2010
Prostate cancer is the second most common cause of cancer-related deaths in Western males. Current diagnostic, prognostic and treatment approaches are not ideal and advanced metastatic prostate cancer is incurable.
Cunningham, Peter Stephen
core   +1 more source

Influence of ghrelin on rat pituitary GH3 cell line proliferation

Journal of Medical Science, 2016
Introduction. Human ghrelin is the endogenous ligand of the growth hormone secretagogue receptor type 1a (GHSR1a). It is suggested that ghrelin is involved in pituitary adenomas pathogenesis. There are inconsistent data regarding the effect of ghrelin on
Małgorzata Chmielewska, Mirosław Andrusiewicz, Aleksandra Żbikowska, Katarzyna Kątniak, Agnieszka Sadowska, Grażyna Arasimowicz-Banaszak, Sławomir Graczyk, Ryszard Waśko, Malgorzata Kotwicka   +8 more
doaj   +1 more source

Frequent Versus Single Active Bouts Differentially Affect Movement Behavior and Energy Balance in Adults With Overweight/Obesity

Obesity, EarlyView.
ABSTRACT Objective This study aimed to investigate the effects of breaking up sedentary behavior (SB) on daily movement behavior and energy balance in adults with overweight/obesity. Methods Thirty participants (16F/14M; 34.2 ± 7.3 years; 29.5 ± 3.2 kg/m2) were randomized to either BREAK (multiple 5‐min brisk walking bouts) or a duration‐matched ...
Heloisa C. Santo Andre, Elisa Le Roux, Nathan P. De Jong, Patricia R. Smith, Andrew H. Lange, Carlos Mendez, Alexandre Zahariev, Melissa L. Mamele, Ginger Johnson, Zhaoxing Pan, Chantal Simon, Daniel H. Bessesen, Ana J. Pinto, Audrey Bergouignan   +13 more
wiley   +1 more source

Avaliação da expressão imuno-histoquímica das células retais produtoras de grelina em ratos Wistar submetidos à dieta de cafeteria [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Ciências Médicas, Florianópolis, 2012Introdução: Na atualidade o sobrepeso e a obesidade, induzidos pela dieta e pelo sedentarismo,
Lyra Junior, Humberto Fenner
core  

Ghrelin and cancer [PDF]

, 2011
Ghrelin is a peptide hormone that was originally isolated from the stomach as the\ud endogenous ligand for the growth hormone secretagogue receptor (GHSR).
Seim, Inge, Murray, Rachael, Herington, Adrian, Carina Walpole, Cunningham, Peter, Adrian Herington, Whiteside, Eliza, Walpole, Carina, Josh, Peter, Peter Josh, Inge Seim, Peter Cunningham, Eliza Whiteside, Murray, Rachael E, Rachael Murray, Chopin, Lisa, Lisa Chopin   +16 more
core   +2 more sources

Expression of ghrelin and ghrelin functional receptor GHSR1a in human pituitary adenomas

Polish Archives of Internal Medicine, 2017
INTRODUCTION    Pituitary adenomas are heterogenous lesions commonly observed in the central nervous system. Signal transduction of ghrelin, an endogenous ligand specific for growth hormone secretagogue receptor (GHSR), has been reported to be involved in the development of endocrine tumors.
Mirosław, Andrusiewicz, Hanna, Komarowska, Izabela, Skibińska, Małgorzata, Chmielewska, Magdalena, Jaskuła-Świtek, Włodzimierz, Liebert, Ryszard, Waśko, Małgorzata, Kotwicka   +7 more
openaire   +2 more sources