Results 101 to 110 of about 3,121 (172)
Constitutive and ghrelin-dependent GHSR1a activation impairs CaV2.1 and CaV2.2 currents in hypothalamic neurons [PDF]
, 2015 The growth hormone secretagogue receptor type 1a (GHSR1a) has the highest constitutive activity of any G protein coupled receptor (GPCR). GHSR1a mediates the action of the hormone ghrelin and, its activation increases transcriptional and electrical ...
Agosti +76 more
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Molecular Metabolism, 2019 Dopamine neurons in the Substantia nigra (SN) play crucial roles in control of voluntary movement. Extensive degeneration of this neuronal population is the cause of Parkinson's disease (PD). Many factors have been linked to SN DA neuronal survival, including neuronal pacemaker activity (responsible for maintaining basal firing and DA tone) and ...
Bernardo Stutz +8 more
openaire +4 more sources
Thermal Emission Control with One-Dimensional Metallodielectric Photonic Crystals [PDF]
, 2004 We have analyzed thermal emission from one-dimensional metallodielectric periodic structures using a Green’s function technique together with the fluctuation-dissipation theorem.
Chen, Gang, Narayanaswamy, Arvind
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Reproductive Biology and Endocrinology, 2007 Background Ghrelin is an orexigenic hormone principally produced by the stomach, but also by numerous peripheral tissues including the placenta. Ghrelin acts via growth hormone secretagogue receptors (GHSR-1a) to alter food intake, fat utilization, and ...
Wallace Jacqueline M +6 more
doaj +1 more source
Dos peptídeos liberadores do hormônio de crescimento (HC) à ghrelina: descoberta de novos moduladores da secreção de HC [PDF]
, 2006 Growth hormone (GH)-releasing hormone and somatostatin modulate GH secretion. A third mechanism has been discovered in the last decade, involving the action of GH secretagogues.
Lengyel, Ana Maria Judith
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Midbrain ghrelin receptor signalling regulates binge drinking in a sex specific manner
Nature CommunicationsRisky drinking rates are rising, particularly in women, yet sex as a biological variable has only recently gained traction. The centrally projecting Edinger-Westphal (EWcp) nucleus has emerged as a key regulator of alcohol consumption. Here we found that
Amy J. Pearl +10 more
doaj +1 more source
GHS-R1a constitutive activity and its physiological relevance
Frontiers in Neuroscience, 2013 Abundant evidences have shown that ghrelin, by its binding to GHS-R1a, plays an important role for fundamental physiological functions. Increasing attention is given to the GHS-R1a unusually high constitutive activity and its contribution to downstream ...
Yves Louis MEAR +3 more
doaj +1 more source
Studies on the antidepressant-like effect and prokinetic-like effects and the underlying mechanisms of Fructus aurantii and meranzin hydrate [PDF]
, 2016 目的：测定代表中药枳壳汤剂抗抑郁促动力(A&P)的吸收成分，初步阐明其A&P特别是抗抑郁的作用机理。 方法：1.含量测定。运用HPLC/MS/MS测定枳壳汤剂在空肠，海马和前额叶皮层吸收成分；2.急性抗抑郁疗效测试。该实验包括枳壳汤剂及其吸收成分水合橙皮内酯的急性抗抑郁疗效测试。该测试包括强迫游泳实验、旷场实验、习得性无助实验和新奇抑制实验；3.水合橙皮内酯的慢性抗抑郁疗效测试。包括强迫游泳实验和旷场实验；4.离体和在体胃肠动力实验；5.抗抑郁机制研究和抗抑郁促动力的共性机制研究 ...
柳进
core
A large and unusual lung abscess with positive culture to Slackia exigua
International Journal of Infectious Diseases, 2015 C. Roingeard +2 more
doaj +1 more source