Results 121 to 130 of about 5,420 (161)

Lipids modulate the dynamics of GPCR:β-arrestin interaction. [PDF]

Nat Commun
Gomes AAS, Di Michele M, Roessner RA, Damian M, Bisch PM, Sibille N, Louet M, Banères JL, Floquet N.   +8 more
europepmc   +1 more source

Obesity-Induced PVAT Dysfunction and Atherosclerosis Development: The Role of GHSR-1a in Increased Macrophage Infiltration and Adipocytokine Secretion. [PDF]

J Cardiovasc Dev Dis
Peiu SN, Zugun-Eloae F, Stoica B, Anisie E, Iosep DG, Danciu M, Silivestru-Crețu I, Akad F, Avadanei AN, Condur L, Popa RF, Mocanu V.   +11 more
europepmc   +1 more source

Determination of Biotin Interference in Pediatric Obesity Related ELISA Research Kits Biotin Interference in Manual ELISA Kits. [PDF]

J Clin Lab Anal
Kürkçü Kahraman E, Donma O, Donma MM, Yılmaz A, Güzel S.   +4 more
europepmc   +1 more source

MRAP2 potentiates GPCR signaling by conserved mechanisms that are disrupted by obesity-associated genetic variants

Jamaluddin A, Wyatt RA, Broichhagen J, Levitz J, Gorvin CM.   +4 more
europepmc   +1 more source

Ghrelin-GHSR system in the eye: local regulation and pathophysiological implications

, 2013
openaire   +2 more sources

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Therapeutic potential of GHSR-1A antagonism in alcohol dependence, a review

Life Sciences, 2022
Growth hormone secretagogue receptor type 1A (GHSR-1A) is a functional receptor of orexigenic peptide ghrelin and is highly expressed in mesolimbic dopaminergic systems that regulate incentive value of artificial reward in substance abuse. Interestingly, GHSR-1A has also shown ligand-independent constitutive activity.
Shreyasi Gupta, Arkadeep Mitra, Sanchari Mukhopadhyay   +2 more
exaly   +3 more sources

The protective effects of Ghrelin/GHSR on hippocampal neurogenesis in CUMS mice

Neuropharmacology, 2019
Ghrelin is an orexigenic hormone that also plays an important role in mood disorders. Our previous studies demonstrated that ghrelin administration could protect against depression-like behaviors of chronic unpredictable mild stress (CUMS) in rodents. However, the mechanism related to the effect of ghrelin on CUMS mice has yet to be revealed.
Na Yue, Yan-Qing Wang, Qiong Liu
exaly   +3 more sources

Molecular cloning and analysis of the ghrelin/GHSR system in Xenopus tropicalis

General and Comparative Endocrinology, 2023
Ghrelin is a gut-derived peptide with several physiological functions, including feeding, gastrointestinal motility, and hormonal secretion. Recently, a host defense peptide, liver-expressed antimicrobial peptide-2 (LEAP2), was reported as an endogenous antagonist of growth hormone secretagogue receptor (GHS-R).
Reiko, Wada, Shota, Takemi, Mio, Matsumoto, Mio, Iijima, Takafumi, Sakai, Ichiro, Sakata   +5 more
openaire   +2 more sources

Adenosine is not a direct GHSR agonist – artificial cross‐talk between GHSR and adenosine receptor pathways

Acta Physiologica, 2007
AbstractAim: To assess if adenosine is a direct growth hormone secretagogue receptor (GHSR) agonist by investigating the mechanism behind adenosine induced calcium release in human embryonic kidney 293s (HEK) cells expressing GHSR.Methods: Calcium mobilization, cyclic adenosine monophosphate (cAMP) and IP3experiments were performed using HEK cells ...
N-O, Hermansson, D G A, Morgan, T, Drmota, N, Larsson   +3 more
openaire   +2 more sources