Results 121 to 130 of about 6,435 (196)

LEAP2 Regulates Insulin Secretion from INS-1E Beta Cells and Rat Pancreatic Islets: An In Vitro Study. [PDF]

Int J Mol Sci
Sosiński O, Pruszyńska-Oszmałek E, Sassek M, Leciejewska N, Pawlak P, Kołodziejski PA.   +5 more
europepmc   +1 more source

Meta-inflammation through the lens of macrophage programming and nutrient-sensing ghrelin signaling. [PDF]

Immunometabolism (Cobham)
Han HW, Kim DM, Eshghjoo S, Xu C, Liu Z, Patil BS, Guo S, Sun Y.   +7 more
europepmc   +1 more source

The Ghrelin-LEAP2 System in Obesity and Diabetes: Pathophysiological Roles and Therapeutic Potential. [PDF]

Curr Obes Rep
Valdés-Calero I, Frühbeck G, Rodríguez A.   +2 more
europepmc   +1 more source

Obesity as the Sequel of Childhood Stunting: Ghrelin and GHSR Gene Polymorphism Explained.

Acta medica Indonesiana, 2018
Stunting or short stature in children is a significant nutritional problem in developing and underdeveloped countries. Stunting during childhood might affect brain development and impair development cognitive function. Additionally, this condition associated with the increased risk for obesity during adulthood.
openaire   +3 more sources

The 5:2 diet induces male-specific weight loss and sex-independent enhancement of lipid storage in mice via activation of GHSR. [PDF]

Front Nutr
Hornsby AKE, Powell ODT, Guschina IA, Williams TJ, Lines KD, Roberts LD, Davies JS, Wells T.   +7 more
europepmc   +1 more source

Preliminary investigation of ghrelin in horses and ponies: receptor expression and associations with prandial state, morphometry and signalment. [PDF]

BMC Vet Res
Andrews KE, Smith HL, Spence RJ, Sillence MN, de Laat MA.   +4 more
europepmc   +1 more source

GHSR antagonist LEAP2 concentrations negatively correlate with alcohol craving and are modulated by alcohol exposure: Evidence from human and rat studies. [PDF]

Drug Alcohol Depend
Leko AH, Farokhnia M, Tressler EH, Vendruscolo JCM, Kryszak LA, Jackson SN, Farinelli LA, Jennings O, Yang Z, Haass-Koffler CL, Vendruscolo LF, Liangpunsakul S, Leggio L.   +12 more
europepmc   +1 more source

Development of potent GHSR inverse agonists: promising compounds for the treatment of obesity-related metabolic disorders

International audienceThe GHSR was initially identified as the growth hormone secretagogue receptor. In addition to its ability to stimulate growth hormone secretion, this G protein-coupled receptor is also involved in the regulation of several essential
Perello, Mario, Bouacha, Célia, M'Kadmi, Céline, Cantel, Sonia, Ben Haj Salah, Khoubaib, Oiry, Catherine, Neasta, Jérémie, Baneres, Jean‐louis, Fehrentz, Jean-Alain, Denoyelle, Séverine   +9 more
core  

Membrane cholesterol modulates engagement of β-arrestin with the ghrelin receptor. [PDF]

Commun Biol
Berto L, Henri P, Damian M, Cantel S, Fehrentz JA, Sibille N, Di Michele M, Banères JL.   +7 more
europepmc   +1 more source

Edinger-Westphal Neurons Contribute to Emergence from Desflurane and Sevoflurane Anesthesia in Mice. [PDF]

J Neurosci
Hu 胡译文 Y, Huang 黄静 J, Bai 白福海 F, Yang 杨静 J, Long 龙宗泓 Z, Li 李钰 Y, Zhang 张敏 M, Huang 黄露 L, Wu 吴卓熙 Z, Yi 易婷婷 T, Li 李洪 H.   +10 more
europepmc   +1 more source