Results 101 to 110 of about 465,440 (235)

Phase separation on giant liposomes prepared by gel-assisted swelling.

Biophysical Journal, 2023
Khasey Keith, Yifei Wang, Sheereen Majd
semanticscholar   +1 more source

Direct binding of phosphatidylglycerol at specific sites modulates desensitization of a ligand-gated ion channel [PDF]

, 2019
Pentameric ligand-gated ion channels (pLGICs) are essential determinants of synaptic transmission, and are modulated by specific lipids including anionic phospholipids.
Brannigan, Grace, Cheng, Wayland W.L., Hsu, Fong-Fu, Nimigean, Crina M, Petroff II, John T, Schmidpeter, Philipp A.M., Sharp, Liam, Tong, Ailing   +7 more
core   +1 more source

Permeability of phospholipid membrane for small polar molecules determined from osmotic swelling of giant phospholipid vesicles

, 2012
A method for determining permeability of phospholipid bilayer based on the osmotic swelling of micrometer-sized giant unilamellar vesicles (GUVs) is presented as an alternative to the two established techniques, dynamic light scattering on liposome ...
Al-Awqati, Angelova, Bangham, Bangham, Barry, Bloom, Boroske, Brunner, Carlsen, Cohen, de Gier, de Gier, Diamant, Dimova, Döbereiner, Evans, Finkelstein, Haleva, Heimburg, Heinrich, Hill, Jacobs, Karatekin, Katchalsky, Kedem, Kleinhans, Koslov, Krasteva, Mally, Mally, Mazur, Mazur, Meyer, Missner, Montal, Mueller, Nagle, Onsager, Onsager, Orbach, Overton, Paula, Pavlič, Pencer, Pencer, Peterlin, Peterlin, Peterlin, Pike, Pocivavsek, Popescu, Preston, Rawicz, Sandre, Seifert, Sha'afi, Shoemaker, Tien, Verkman, Walter, Wang, Zade-Oppen   +61 more
core   +1 more source

Electroformation in a flow chamber with solution exchange as a means of preparation of flaccid giant vesicles

, 2008
A recently described technique (Estes and Mayer, Biochim. Biophys. Acta 1712 (2005) 152--160) for the preparation of giant unilamellar vesicles (GUVs) in solutions with high ionic strength is examined.
Akashi, Angelova, Angelova, Angelova, Angelova, Bagatolli, Bloom, Božič, Bresseleers, Deamer, Dimova, D’Errico, Estes, Estes, Estes, Evans, Heinrich, Hope, Koslov, Kralj-Iglič, Kuribayashi, Mally, Mally, Mathivet, Morse, Moscho, Needham, Okumura, Olbrich, Orbach, Paula, Paula, Primož Peterlin, Redelmeier, Reeves, Riske, Rodriguez, Taylor, Ternström, Vesna Arrigler, Yamashita   +40 more
core   +1 more source

α-Synuclein Dimers Impair Vesicle Fission during Clathrin-Mediated Synaptic Vesicle Recycling

Frontiers in Cellular Neuroscience, 2017
α-Synuclein is a presynaptic protein that regulates synaptic vesicle (SV) trafficking. In Parkinson’s disease (PD) and several other neurodegenerative disorders, aberrant oligomerization and aggregation of α-synuclein lead to synaptic dysfunction and ...
Audrey T. Medeiros, Lindsey G. Soll, Isabella Tessari, Luigi Bubacco, Jennifer R. Morgan   +4 more
doaj   +1 more source

Mechanical power is maximized during contractile ring-like formation in a biomimetic dividing cell model

Nature Communications
The spatial and temporal dynamics of forces in cells coordinate essential behaviors like division, polarization, and migration. While intracellular signaling initiates contractile ring assembly during cell division, how mechanical forces coordinate ...
Ryota Sakamoto, Michael P. Murrell
doaj   +1 more source

Interaction of two antitumor peptides with membrane lipids - Influence of phosphatidylserine and cholesterol on specificity for melanoma cells.

PLoS ONE, 2019
R-DIM-P-LF11-322 and DIM-LF11-318, derived from the cationic human host defense peptide lactoferricin show antitumor activity against human melanoma. While R-DIM-P-LF11-322 interacts specifically with cancer cells, the non-specific DIM-LF11-318 exhibits ...
Christina Wodlej, Sabrina Riedl, Beate Rinner, Regina Leber, Carina Drechsler, Dennis R Voelker, Jae-Yeon Choi, Karl Lohner, Dagmar Zweytick   +8 more
doaj   +1 more source

Pepticombisomes: Biomimetic Vesicles Crafted From Recombinant Supercharged Polypeptides with Uniformly Distributed Side‐Chains

Advanced Science
Cell membranes play a key role in bottom‐up synthetic biology, as they enable interaction control, transport, and other essential functions. These ultra‐thin, flexible, yet stable structures form through the self‐assembly of lipids and proteins.
Dominik Söder, Melina Schadt, Vladislav S. Petrovskii, Tamás Haraszti, Khosrow Rahimi, Igor I. Potemkin, Nina Yu. Kostina, Cesar Rodriguez‐Emmenegger, Andreas Herrmann   +8 more
doaj   +1 more source

Benefits of Combined Fluorescence Lifetime Imaging Microscopy and Fluorescence Correlation Spectroscopy for Biomedical Studies Demonstrated by Using a Liposome Model System

Biophysica
Drug delivery systems play a pivotal role in targeted pharmaceutical transport and controlled release at specific sites. Liposomes, commonly used as drug carriers, constitute a fundamental part of these systems.
Kristina Bruun, Hans-Gerd Löhmannsröben, Carsten Hille   +2 more
doaj   +1 more source

Encapsulation of protein/DNA complexes into unilamellar liposomes via annexin-mediated membrane recruitment and sonication

Cell Reports: Methods
Summary: This paper reports an effective protocol to encapsulate native protein/DNA complexes into unilamellar vesicles composed of natural lipids without the use of organic solvents, in physiological buffers, and at low protein/DNA concentrations.
Michael Burger, Finn Brigger, Valeria Mantella, Jean-Christophe Leroux   +3 more
doaj   +1 more source