Results 11 to 20 of about 5,077 (168)
Engineering Phosphatidylserine Containing Asymmetric Giant Unilamellar Vesicles
MembranesThe plasma membrane lipid distribution is asymmetric, with several anionic lipid species located in its inner leaflet. Among these, phosphatidylserine (PS) plays a crucial role in various important physiological functions.
Arne Gericke +2 more
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High-Speed Imaging of Giant Unilamellar Vesicle Formation in cDICE [PDF]
ACS Omega, 2023 Abstract Giant unilamellar vesicles (GUVs) are widely used as in vitro model membranes in biophysics and as cell-sized containers in synthetic biology. Despite their ubiquitous use, there is no one-size-fits-all method for their production.
Lori Van de Cauter +7 more
doaj +5 more sources
The impact of sphingomyelin and cholesterol on ordered lipid domain formation in the bovine milk fat globule membrane using artificial giant unilamellar vesicles as a model [PDF]
JDS CommunicationsGiant unilamellar vesicle (GUV) bilayers were constructed from polar lipids and cholesterol by electroformation as a model system to investigate the formation of ordered lipid domains (OLD) within the milk fat globule membrane (MFGM).
Haotian Zheng +2 more
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Mechanisms of Self-Assembly of Giant Unilamellar Vesicles in the Army Liposome Formulation (ALF) Family of Vaccine Adjuvants [PDF]
PharmaceuticsBackground/Objectives: Army Liposome Formulation with QS21 (ALFQ) is a vaccine adjuvant formulation consisting of liposomes that contain saturated zwitterionic and anionic phospholipids, 55 mol% cholesterol, and small molar amounts of monophosphoryl ...
Calin Nicolescu +4 more
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One-Pot Assembly of Complex Giant Unilamellar Vesicle-Based Synthetic Cells [PDF]
ACS Synthetic Biology, 2019 Yannik Dreher +2 more
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Division and Regrowth of Phase‐Separated Giant Unilamellar Vesicles** [PDF]
Angewandte Chemie International Edition, 2021 AbstractSuccess in the bottom‐up assembly of synthetic cells will depend on strategies for the division of protocellular compartments. Here, we describe the controlled division of phase‐separated giant unilamellar lipid vesicles (GUVs). We derive an analytical model based on the vesicle geometry, which makes four quantitative predictions that we verify
Yannik Dreher +4 more
openaire +5 more sources
Bio-Protocol, 2022 Transbilayer movement of phospholipids in biological membranes is mediated by a diverse set of lipid transporters. Among them are scramblases that facilitate rapid bi-directional movement of lipids without metabolic energy input.
Patricia Mathiassen +1 more
doaj +1 more source
Membranes, 2022 Yeast S. cerevisiae has been shown to suppress a sterol biosynthesis as a response to hyperosmotic stress. In the case of sodium stress, the failure to suppress biosynthesis leads to an increase in cytosolic sodium. The major yeast sterol, ergosterol, is
Svyatoslav S. Sokolov +8 more
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Hierarchical unilamellar vesicles of controlled compositional heterogeneity. [PDF]
PLoS ONE, 2012 Eukaryotic life contains hierarchical vesicular architectures (i.e. organelles) that are crucial for material production and trafficking, information storage and access, as well as energy production. In order to perform specific tasks, these compartments
Maik Hadorn +3 more
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Asymmetric Giant Unilamellar Vesicles [PDF]
Biophysical Journal, 2010 The lipid composition of the eukaryotic plasma membrane is asymmetric; that is, if the bilayer is considered to consist of two leaflets, the outer-facing leaflet contains different lipids at different concentrations than the inner-facing leaflet. While there has been much speculation as to the physiological purpose of this asymmetry, it has been ...
Hu, Peichi C., Malmstadt, Noah
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