Results 21 to 30 of about 23,127 (230)

Engineering Phosphatidylserine Containing Asymmetric Giant Unilamellar Vesicles

open access: yesMembranes
The plasma membrane lipid distribution is asymmetric, with several anionic lipid species located in its inner leaflet. Among these, phosphatidylserine (PS) plays a crucial role in various important physiological functions.
Jake McDonough   +5 more
doaj   +3 more sources

The impact of sphingomyelin and cholesterol on ordered lipid domain formation in the bovine milk fat globule membrane using artificial giant unilamellar vesicles as a model [PDF]

open access: yesJDS Communications
Giant unilamellar vesicle (GUV) bilayers were constructed from polar lipids and cholesterol by electroformation as a model system to investigate the formation of ordered lipid domains (OLD) within the milk fat globule membrane (MFGM).
Haotian Zheng   +2 more
doaj   +2 more sources

Mechanisms of Self-Assembly of Giant Unilamellar Vesicles in the Army Liposome Formulation (ALF) Family of Vaccine Adjuvants [PDF]

open access: yesPharmaceutics
Background/Objectives: Army Liposome Formulation with QS21 (ALFQ) is a vaccine adjuvant formulation consisting of liposomes that contain saturated zwitterionic and anionic phospholipids, 55 mol% cholesterol, and small molar amounts of monophosphoryl ...
Calin Nicolescu   +4 more
doaj   +2 more sources

Structural and Functional Effects of the Interaction Between an Antimicrobial Peptide and Its Analogs with Model Bacterial and Erythrocyte Membranes [PDF]

open access: yesBiomolecules
Antimicrobial peptides (AMPs) are a primary defense against pathogens. Here, we examined the interaction of two BP100 analogs, R2R5-BP100 (where Arg substitutes Lys 2 and 5) and R2R5-BP100-A-NH-C16 (where an Ala and a C16 hydrocarbon chain are added to ...
Michele Lika Furuya   +12 more
doaj   +2 more sources

The dynamics of giant unilamellar vesicle oxidation probed by morphological transitions.

open access: yesBiochimica Et Biophysica Acta - Biomembranes, 2014
Shalene Sankhagowit   +5 more
semanticscholar   +3 more sources

Instant Membrane Stabilization by Damage-Triggered Actin Polymerization in Giant Unilamellar Vesicles. [PDF]

open access: yesChembiochem
Damage‐triggered actin polymerization stabilizes membrane pores in giant unilamellar vesicles (GUVs). Membrane poration drives divalent cation influx, inducing rapid F‐actin assembly at the defect site. The resulting actin plug mechanically arrests pore expansion and preserves vesicle morphology, recapitulating the “plugging” phase of single‐cell ...
Nguyen HT, Lee SH, Kim CH, Shin K.
europepmc   +2 more sources

A Fluorescence-based Assay for Measuring Phospholipid Scramblase Activity in Giant Unilamellar Vesicles

open access: yesBio-Protocol, 2022
Transbilayer movement of phospholipids in biological membranes is mediated by a diverse set of lipid transporters. Among them are scramblases that facilitate rapid bi-directional movement of lipids without metabolic energy input.
Patricia Mathiassen   +1 more
doaj   +1 more source

Exploring Giant Unilamellar Vesicle Production for Artificial Cells — Current Challenges and Future Directions

open access: yesSmall Methods, 2023
Creating an artificial cell from the bottom up is a long‐standing challenge and, while significant progress has been made, the full realization of this goal remains elusive.
Lori van de Cauter   +3 more
semanticscholar   +1 more source

Structural Role of Plasma Membrane Sterols in Osmotic Stress Tolerance of Yeast Saccharomyces cerevisiae

open access: yesMembranes, 2022
Yeast S. cerevisiae has been shown to suppress a sterol biosynthesis as a response to hyperosmotic stress. In the case of sodium stress, the failure to suppress biosynthesis leads to an increase in cytosolic sodium. The major yeast sterol, ergosterol, is
Svyatoslav S. Sokolov   +8 more
doaj   +1 more source

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